31 citations
,
September 2011 in “European journal of pharmaceutics and biopharmaceutics” This study found that biodegradable PLA particles released fluorochromes in a time-dependent manner on human skin, with BP-PLA particles releasing rapidly and DiAsp-PLA particles providing sustained release and accumulation in hair follicles.
31 citations
,
January 1989 in “Clinical and Experimental Dermatology” In this study, topical 2% minoxidil did not significantly improve hair density measures in men with male pattern baldness, although there was no deterioration, suggesting a potential prophylactic effect.
30 citations
,
June 2017 in “Journal of cutaneous medicine and surgery” This study reports that topical ruxolitinib failed to induce hair growth in a 66-year-old patient with alopecia areata, highlighting the need to explore factors affecting treatment response and compare topical vs oral administration outcomes.
30 citations
,
September 2011 in “International Wound Journal” This study found that platelet-rich plasma therapy significantly improved wound area and depth reduction in chronic wounds compared to pre-treatment, suggesting registry data can effectively complement traditional clinical trials.
30 citations
,
September 2003 in “Experimental Dermatology” In this study on a murine model, researchers observed that a 5% minoxidil solution reduced stress-induced changes in hair growth, suggesting its potential for managing stress-related hair loss in humans.
30 citations
,
January 1997 in “Journal of Dermatological Treatment” This study reported that a 0.005% finasteride solution may encourage hair regrowth and reduce balding areas in patients with androgenic alopecia, without significant absorption or adverse effects.
30 citations
,
April 1990 in “Clinical Pharmacology & Therapeutics” This study found that coadministering minoxidil with tretinoin cream increased minoxidil absorption nearly threefold in healthy males, attributed to increased stratum corneum permeability.
29 citations
,
December 2021 in “Pharmaceutics” This review discusses the use of phospholipid soft vesicle carriers to improve the delivery and therapeutic outcomes of topical treatments for various skin conditions, but reports no new clinical results.
29 citations
,
April 2019 in “Lasers in Medical Science” This study found that combining fractional erbium-glass laser therapy with topical minoxidil significantly improved hair density and diameter in men with androgenetic alopecia compared to using minoxidil alone over a 24-week period, with no serious adverse events reported.
29 citations
,
July 2009 in “Journal of Dermatology” This study confirmed that 5% topical minoxidil is more effective than 1% in increasing hair density in Japanese men with androgenetic alopecia, with no significant difference in adverse event rates.
29 citations
,
December 2003 in “Teratology” This case report describes fetal malformations and placental abnormalities in a pregnant woman who applied minoxidil topically, suggesting potential risks of its use during pregnancy.
28 citations
,
July 2015 in “Dermatologic therapy” This study found that combining topical and oral pulse corticosteroid therapy for severe alopecia areata in children led to long-lasting hair regrowth, especially in AA plurifocalis, with no serious side effects reported.
28 citations
,
December 2005 in “Journal of cosmetic dermatology” This study found that 0.7% apple procyanidin oligomers applied externally for six months significantly increased hair growth in men with male pattern baldness compared to placebo, with no observed adverse effects.
28 citations
,
January 2005 in “PubMed” This review discusses the use, mechanism, and side effects of topical immunomodulators in treating immune-mediated skin disorders and reports no new clinical results, urging further research on experimental agents.
28 citations
,
May 1994 in “The Journal of Urology” This study found that topical application of 2% minoxidil solution was not effective in improving erectile dysfunction in the majority of participants.
28 citations
,
March 1987 in “Journal of The American Academy of Dermatology” This study observed that two out of twelve patients showed hair growth without the usual shedding after hair transplant surgery when treated with topical minoxidil, suggesting its potential as an adjunctive therapy during recovery.
27 citations
,
December 2005 in “Journal of Cosmetic Dermatology” This study found that topical application of niacin derivatives significantly increased hair fullness in women with female pattern hair loss compared to a placebo after six months.
27 citations
,
January 1989 in “The Journal of dermatologic surgery and oncology” This study found that using 2% topical minoxidil before and after hair transplantation may improve graft outcomes by reducing initial shedding in patients with androgenetic alopecia.
26 citations
,
December 2019 in “Indian Journal of Dermatology, Venereology and Leprology” This study found that platelet-rich plasma combined with topical minoxidil was more effective in increasing hair density for male-type baldness than either treatment alone.
26 citations
,
March 2015 in “American journal of clinical dermatology” This study found that systemic mycophenolate mofetil and topical clobetasol were equally effective at reducing lichen planopilaris activity over six months, but satisfaction differed between the treatments.
26 citations
,
March 2014 in “Journal of cutaneous medicine and surgery” This study provides evidence-based recommendations for the off-label use of topical vitamin D in treating certain skin conditions, but highlights the need for higher quality studies for further validation.
26 citations
,
January 2012 in “Journal of the American Academy of Dermatology” This study found that adding topical eflornithine to hair laser treatment significantly reduced hair counts and inflammatory papules more effectively than laser therapy alone in treating pseudofolliculitis barbae.
26 citations
,
December 2006 in “Endocrinology” This study found that a topical cream containing PTH (7–34) significantly stimulated hair growth in hairless mice.
26 citations
,
January 2005 in “PubMed” This study reports that RU 58841-myristate, a new antiandrogen prodrug formulated with solid lipid nanoparticles, shows potential for targeting hair follicles in preclinical laboratory settings.
26 citations
,
July 2003 in “Journal of Cutaneous Medicine and Surgery” This study found that topical minoxidil solution is a safe treatment for androgenetic alopecia, with no increase in cardiovascular events or adverse pregnancy outcomes observed.
26 citations
,
March 1994 in “Archives of Dermatology” This study found that a 2% topical minoxidil solution was significantly more effective than a placebo in promoting hair growth in women with androgenetic alopecia over 32 weeks.
26 citations
,
June 1988 in “PubMed” This study found that 3 percent topical minoxidil solution was ineffective in treating severe chronic alopecia areata, as it did not produce cosmetically acceptable hair regrowth.
26 citations
,
January 1987 in “Dermatology” This study reported that topical 2% minoxidil solution improved hair growth compared to placebo in men with early male-pattern baldness over 24 weeks, with no significant safety issues observed.
26 citations
,
January 1987 in “Archives of Dermatology” In this study, topical minoxidil did not show an antiandrogenic effect on androgen-dependent cutaneous structures in the golden Syrian hamster, suggesting it likely does not have this role in humans either.
26 citations
,
March 1985 in “International Journal of Dermatology” Minoxidil helps hair growth, but results vary.