8 citations
,
February 2005 in “International Journal of Cosmetic Science” The study found that applying Bifidobacterium-fermented soy milk extract to human skin significantly reduced the decline in skin elasticity, suggesting its potential as a cosmetic ingredient to prevent skin aging.
8 citations
,
April 1988 in “Journal of endocrinological investigation” This study found that topically administered spironolactone in healthy volunteers resulted in no detectable systemic absorption or changes in related hormone levels over 72 hours, indicating local effect only.
8 citations
,
May 1987 in “Journal of The American Academy of Dermatology” In this study, ultraviolet light did not significantly enhance or worsen hair growth induced by topical minoxidil in men with male pattern baldness.
7 citations
,
March 2023 in “European Journal of Dermatology” Using Selenium Disulfide shampoo weekly helps prevent scalp dermatitis flare-ups.
7 citations
,
January 2022 in “Bioengineering” This study found that a lipid-based nanoparticle formulation with oleic acid for delivering dutasteride showed lower skin permeation compared to a formulation without oleic acid, indicating its potential for targeted dermal delivery.
7 citations
,
April 2021 in “British Journal of Dermatology” In this research letter from the British Journal of Dermatology, the authors explore the use of topical tofacitinib to treat alopecia areata affecting facial hair, but specific results are not reported in the abstract.
7 citations
,
January 2021 in “Cureus” This case report describes a 27-year-old woman who experienced facial swelling due to allergic contact dermatitis from using minoxidil 5% foam.
7 citations
,
July 2020 in “Pigment cell & melanoma research” In this study, RT1640 was found to promote hair pigment system regeneration and expand melanocyte stem cell pools in a mouse model, suggesting potential applications for aging-related hair disorders.
7 citations
,
December 2019 in “American Journal of Clinical Dermatology” This review discusses the potential efficacy of topical antiandrogen therapies for treating androgenetic alopecia and acne vulgaris, finding promising results but highlighting the need for more comprehensive studies.
7 citations
,
February 2019 in “Veterinary medicine and science” This study reports the first identification of the deleterious NIPAL 4 variant, associated with autosomal recessive congenital ichthyosis, in an American Bully and describes its clinical management and follow-up.
7 citations
,
October 2018 in “Dermatology practical & conceptual” This study found that topical oxygen therapy may be a beneficial adjuvant treatment for hair loss, acne, and chronic dermatological conditions, though further research is needed to confirm its effectiveness.
7 citations
,
May 2018 in “Curēus” In this case report, a 60-year-old woman with eyebrow hypotrichosis experienced significant and lasting eyebrow growth after daily use of bimatoprost 0.03% solution, highlighting its potential as an effective treatment for eyebrow hair restoration.
7 citations
,
July 2016 in “PubMed” This study found that laser Doppler velocimetry can non-invasively predict topical minoxidil response by correlating scalp blood flow changes with sulfotransferase enzyme activity in women with pattern hair loss.
7 citations
,
March 2015 in “British Journal of Dermatology” Applying minoxidil can help improve hair growth in people with hair loss caused by LIPH gene mutations.
7 citations
,
January 2015 in “International Journal of Trichology” This case report describes a woman who experienced frontal edema after topical minoxidil application following mesotherapy, noting that excessive absorption of minoxidil may cause localized vasodilatory side effects.
7 citations
,
October 2012 in “PubMed” This study found that intralesional triamcinolone was more effective than topical anthralin in promoting hair regrowth in alopecia areata patients, but it also had a higher relapse rate.
7 citations
,
April 2011 in “American journal of obstetrics and gynecology” This case report highlights the importance of considering exogenous androgen exposure, such as transdermal testosterone cream used by a partner, in the diagnosis of virilization among women.
7 citations
,
April 2009 in “Bioorganic & Medicinal Chemistry Letters” Diphenyl ethers can potentially reduce excess oil production when applied on the skin, helping treat conditions like acne.
7 citations
,
January 2009 in “International Journal of Trichology” In this study, researchers found that dermoscopy does not provide distinguishing features for diagnosing scalp contact dermatitis from topical minoxidil compared to other causes of severe scalp itching.
7 citations
,
June 2000 in “Journal of the American Academy of Dermatology” This study found that betamethasone valerate in a foam vehicle has comparable total coverage to traditional topical corticosteroid vehicles, despite less coverage per unit of foam.
7 citations
,
September 1991 in “PubMed” This study found that 2 percent topical minoxidil significantly increased nonvellus hair count and showed moderate regrowth compared to placebo in women with mild to moderate androgenetic alopecia, although participants did not notice the difference.
7 citations
,
November 1987 in “Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy” This article reviews the potential of topical minoxidil to cosmetically thicken hair in some individuals with male pattern hair loss, but it reports no new clinical results.
7 citations
,
January 1987 in “Archives of Dermatology” This study reports that over 70% of responding dermatologists prescribed topical minoxidil, but a small percentage accounted for most prescriptions and few reported complications beyond local irritation.
6 citations
,
September 2024 in “Metabolism and Target Organ Damage” This review discusses the role of skin enzymes in drug metabolism and emphasizes the need for models assessing enzyme activity to evaluate the safety and bioequivalence of topical generic drugs, highlighting efforts to standardize testing protocols for transdermal products.
6 citations
,
August 2024 in “PubMed” The authors report that topical skincare products containing Coenzyme Q10 can replenish CoQ10 levels, enhance skin's energy metabolism, and reduce the depth of wrinkles by providing antioxidant effects, which may help reverse signs of aging related to oxidative stress.
6 citations
,
May 2024 in “JAAD Case Reports” This study highlights that topical ruxolitinib cream is FDA-approved for mild to moderate atopic dermatitis and nonsegmental vitiligo in patients aged 12 and older, but its use in other skin conditions like frontal fibrosing alopecia remains under-researched and needs further exploration in clinical practice.
6 citations
,
January 2023 in “Annals of Dermatology” This article provides new treatment guidelines for AA based on expert consensus while integrating regional healthcare variations, but it reports no new clinical results.
6 citations
,
January 2021 in “Journal of Cosmetic Dermatology” This study found that combining follicular unit extraction with topical calcipotriol betamethasone dipropionate showed the best repigmentation results in treating stable nonsegmental vitiligo.
6 citations
,
November 2020 in “Chinese Medical Journal” This study found that among Chinese males with male androgenic alopecia, combination therapy using topical minoxidil and nano-microneedle-assisted fibroblast growth factor significantly improved hair density, diameter, and follicular unit density over 16 weeks, outperforming individual treatments.
6 citations
,
August 2020 in “Journal of Pharmaceutical Innovation” This study found that a lipid nanoemulsion-based gel of finasteride for topical use improved hair growth and was effective against alopecia, with slow skin permeation and increased efficacy compared to a testosterone-treated group.