13 citations
,
May 1987 in “PubMed” This review explores the mechanisms and clinical trials of topical minoxidil for hair loss but presents no new clinical findings, emphasizing the need for better understanding of hair loss etiology for effective treatments.
13 citations
,
December 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study observed that nicotinamide can effectively inhibit human hair growth and promote hair follicle regression in cultured human scalp models without negatively affecting epidermal vitality, suggesting its potential as a hair growth inhibitor in cosmetic applications.
12 citations
,
July 2020 in “International Journal of Pharmaceutics” This study found that finasteride- and dutasteride-loaded iron oxide nanoparticles improved drug penetration in the skin, suggesting they may be promising for topical alopecia therapies.
12 citations
,
July 2020 in “Dermatologic Therapy” This review discusses the use of topical and oral minoxidil for pediatric hair disorders, pointing out the lack of guidelines and the potential risks associated with systemic absorption, but reports no clinical results.
12 citations
,
September 2018 in “Dermatologic Therapy” This study found that 14 days of low-dose aspirin reduced the predicted response to topical minoxidil in androgenetic alopecia patients from 50% to 27%, suggesting aspirin may inhibit minoxidil efficacy.
12 citations
,
August 2017 in “Archives of Pharmacal Research” In this study, lecithin-based microparticle formulations of minoxidil showed enhanced skin penetration and comparable hair growth effectiveness to commercial products in mice, while minimizing skin irritation often seen with standard minoxidil solutions.
12 citations
,
October 2015 in “PubMed” This study found that topical minoxidil is more effective than placebo in promoting hair growth in androgenetic alopecia, although cosmetically acceptable results occur only in a subset of patients.
12 citations
,
March 2014 in “ISRN Pharmacology (Print)” This study demonstrated that Ketoconazole, Minoxidil, and Minoxidil with Tretinoin all significantly stimulated hair growth in mice, with Minoxidil alone showing the most effectiveness.
12 citations
,
March 2013 This report describes a case where a 4-year-old boy with congenital alopecia due to hypohidrotic ectodermal dysplasia experienced significant hair growth after using topical minoxidil.
12 citations
,
September 2012 in “Pediatric Dermatology” This case report describes a 5-year-old boy with extensive epidermal nevus who experienced marked improvement using a topical calcipotriol/betamethasone dipropionate combination ointment.
12 citations
,
January 2008 in “Drugs” This review critically assesses current topical therapies for scalp psoriasis and reports no new clinical results; the authors highlight the need for controlled trials to evaluate treatment efficacy.
12 citations
,
August 2000 in “Fertility and Sterility” Topical finasteride doesn't reduce DHT levels, hinting at an endocrine role in hair loss.
12 citations
,
February 1999 in “British Journal of Dermatology” In this study, topical minoxidil was reported to increase fenestration in follicular capillary walls around anagen hair bulbs in male rats.
11 citations
,
October 2021 in “Journal of The European Academy of Dermatology and Venereology” This study found that topical finasteride significantly increased hair count in men with androgenetic alopecia compared to placebo while maintaining similar efficacy to oral finasteride but with lower systemic exposure and a reduced impact on serum DHT levels, potentially minimizing sexual side effects.
11 citations
,
July 2020 in “Journal of Cosmetic Dermatology” This study found that a 1% Sandalore® solution reduced hair shedding and improved hair volume and anagen phase duration in women with telogen effluvium over 24 weeks, compared to placebo.
11 citations
,
April 2020 in “Journal of Dermatological Treatment” This study found that combining oral isotretinoin with topical treatments was more effective than topical treatments alone for improving frontal fibrosing alopecia symptoms, despite some side effects.
11 citations
,
December 2019 in “Dermatologic Therapy” This systematic review suggests that topical ketoconazole may improve hair regrowth and thickness in both animal and human studies for androgenetic alopecia, but further randomized controlled trials are needed.
11 citations
,
January 2019 in “International Journal of Trichology” This study observed no significant improvement of mesotherapy over 5% topical minoxidil for male androgenic alopecia, despite a small increase in hair shaft diameter variation with mesotherapy.
11 citations
,
October 2017 in “Journal of Investigative Dermatology” This study found that topical application of mitochondrial electron transport chain inhibitors stimulated hair follicle stem cell activation and hair regrowth in aged mice by promoting lactate production.
11 citations
,
April 2015 in “International Journal of Cosmetic Science” This study found that topical adenosine significantly increased the ratio of thick hairs and contributed to global improvement in Japanese men with androgenetic alopecia compared to niacinamide, with no observed adverse events.
11 citations
,
January 2012 in “PubMed” This case report suggests that topical bimatoprost may promote eyebrow hair growth, as observed in a patient with eyebrow hypotrichosis, but lacks broader published scientific evidence.
11 citations
,
April 2011 in “Biomolecules & Therapeutics” This study found that finasteride-containing anionic liposomes enhanced skin retention and had moderate hair growth efficacy, suggesting potential for treating androgenetic alopecia with reduced systemic side effects.
11 citations
,
August 2010 in “Pediatric dermatology” This report details two cases of Lichen spinulosus in the submental area, treated effectively and safely with topical tacalcitol cream.
11 citations
,
January 2010 in “Indian Journal of Dermatology, Venereology and Leprology” Hair transplant and applying 5% minoxidil solution can effectively treat permanent hair loss, but it may change hair direction in some cases.
11 citations
,
April 1997 in “International Journal of Dermatology” This article discusses using topical tretinoin with intralesional triamcinolone acetonide for alopecia areata in northern Saudi Arabia, but it reports no new clinical findings.
11 citations
,
October 1990 in “The Journal of dermatologic surgery and oncology” This review discusses the potential for new retinoids, topical antiandrogens, and alternative therapies to surpass tretinoin in treating cutaneous aging, but reports no clinical results.
11 citations
,
September 1988 in “Annals of Plastic Surgery” This review discusses topical minoxidil for hair growth, reporting about one-third of users gain new hair, noting diminished effects after a year and increased hair loss if stopped, but provides no new experimental results.
11 citations
,
July 1988 in “International Journal of Dermatology” In this study, topically applied 2% minoxidil solution was found to be more effective than placebo for promoting hair regrowth in men with early male pattern baldness over 24 weeks.
11 citations
,
January 1987 in “Dermatology” In this study, 56% of men meeting specific criteria for hair loss experienced cosmetically acceptable hair growth with 2% topical minoxidil after one year, while frontotemporal hair loss did not improve.
11 citations
,
February 1986 in “Archives of Dermatology” This study found that 5% topical minoxidil solution led to better hair regrowth response and quality in severe alopecia areata compared to 1% solution, despite regrowth often being cosmetically unacceptable.