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Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.

GLPLS and LPP are variants of lichen planus.

Serum granulysin levels can indicate the activity and prognosis of alopecia areata.

Tailored treatments for alopecia areata are recommended based on severity and patient needs.

The guidelines help doctors manage skin problems from certain cancer treatments to improve patients' lives.

Colchicine might help treat different skin diseases, but more research is needed to confirm its effectiveness and safe dosage.

Oral feline interferon-omega improved symptoms in diabetic cats with gingivostomatitis.

Some cases of folliculotropic mycosis fungoides may progress slowly and not need aggressive treatment.

The document concludes that more research is needed to find effective treatments for Lichen planopilaris and Frontal fibrosing alopecia.

Some patients on immunosuppressants had a weaker immune response to the Sinovac-CoronaVac COVID-19 vaccine.

Some patients developed hair loss after islet cell transplant possibly due to their immune-suppressing medications.

Both individual and combined treatments of tofacitinib and corticosteroids can help regrow hair in moderate-to-severe alopecia areata, but ongoing treatment may be necessary.

Linagliptin may cause hair loss and skin blisters.

The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.

Higher doses of isotretinoin may lead to more hair loss.

Some skin medications can have harmful interactions with the COVID-19 drug nirmatrelvir-ritonavir, but not with molnupiravir.

Treating non-classic congenital adrenal hyperplasia is complex because the benefits of hormone treatment must be weighed against potential health risks.

Methotrexate is effective and well-tolerated in children for certain skin conditions but requires careful monitoring.

Cepharanthine has many medicinal uses but needs improvement for better effectiveness.

Some antiseizure medications can cause reversible hair loss, with valproate, lamotrigine, and carbamazepine being the most common.

Current alopecia treatments manage symptoms but don't cure, and better treatments are needed.

A Japanese man with rare skin conditions improved with hydroxychloroquine treatment.

Corticosteroid therapy for alopecia areata can cause severe hip bone damage.

The study created 3D-printed pills that effectively release a hair loss treatment drug over 24 hours.

Biologic therapies can cause various adverse events, but allergy/immunology clinicians can manage them.

Fat-derived stem cells show promise for treating skin issues and improving wound healing, but more research is needed to confirm the best way to use them.

High levels of cortisol in hair are linked to a greater risk of brain aneurysm rupture.

Genomic profiling for myeloid cancers can find important inherited mutations, but it's challenging when these mutations aren't related to the patient's symptoms.