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GlossaryTopical Treatments (Topical Lotions)

medications applied directly to the skin or scalp

Topical treatments, also known as topical agents or topical medications, are medications applied directly to a specific area of the skin or scalp to treat localized conditions. These treatments can include creams, gels, ointments, and lotions, and are commonly used for conditions like alopecia, psoriasis, and eczema, delivering active ingredients directly to the affected area to minimize systemic side effects.

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Impact of a Topical Lotion, CG428, on Permanent Chemotherapy-Induced Alopecia in Breast Cancer Survivors: A Pilot Randomized Double-Blind Controlled Clinical Trial (VOLUME RCT)

research Impact of a Topical Lotion, CG428, on Permanent Chemotherapy-Induced Alopecia in Breast Cancer Survivors: A Pilot Randomized Double-Blind Controlled Clinical Trial (VOLUME RCT)

3 citations, July 2019 in “Supportive Care in Cancer”

The lotion CG428 did not show effectiveness in treating permanent hair loss in breast cancer survivors.

research In Vitro Evaluation of Skin Distribution and Human Dermal Papilla Cells Proliferation for Minoxidil 5% Topical Lotion Hydrogel

July 2022 in “Journal of Investigative Dermatology”

The new minoxidil hydrogel is a promising alternative for hair loss treatment, with similar effectiveness and less skin irritation.

research Topical Lotion Beneficial in Androgenetic Alopecia

November 1996 in “Inpharma Weekly”

Lotion with piroctone olamine and triclosan improves hair loss in men.

Management of Chemotherapy-Induced Alopecia Using a Topical Botanical Lotion via a Proposed Triple-Action on Apoptosis, Inflammation, and Collagen

research Management of Chemotherapy-Induced Alopecia Using a Topical Botanical Lotion via a Proposed Triple-Action on Apoptosis, Inflammation, and Collagen

July 2016 in “Cancer Research”

A topical lotion helped manage hair loss from chemotherapy by affecting cell death, inflammation, and collagen, with no side effects.

Efficacy and Safety of a New Topical Hair Loss Lotion Containing Oleanolic Acid, Apigenin, Biotinyl Tripeptide-1, Diaminopyrimidine Oxide, Adenosine, Biotin, and Ginkgo Biloba in Patients with Androgenetic Alopecia and Telogen Effluvium: A Six-Month Open-Label Prospective Clinical Study

research Efficacy and Safety of a New Topical Hair Loss Lotion Containing Oleanolic Acid, Apigenin, Biotinyl Tripeptide-1, Diaminopyrimidine Oxide, Adenosine, Biotin, and Ginkgo Biloba in Patients with Androgenetic Alopecia and Telogen Effluvium: A Six-Month Open-Label Prospective Clinical Study

1 citations, January 2018 in “Journal of cosmetology & trichology”

Hair loss lotion with specific ingredients effectively improves hair growth and thickness safely.

research Efficacy and Safety of a Topical Botanical in Female Androgenetic Alopecia: A Randomized, Single-Blinded, Vehicle-Controlled Study

6 citations, November 2017 in “Skin appendage disorders”

Topical botanical lotion increases hair density and improves quality of life in women with hair loss.

research A Randomized, Single-Blinded, Vehicle-Controlled Study of a Topical Active Blend in the Treatment of Androgenetic Alopecia

4 citations, May 2020 in “Dermatologic Therapy”

Redenyl lotion effectively promotes hair growth and improves quality of life for androgenetic alopecia patients.

Extemporaneous Topical Minoxidil Solutions for the Treatment of Androgenetic Alopecia: Stability Studies and Incorporation Tests of Active Pharmaceutical Ingredients in Aloplus Total Base

research Extemporaneous Topical Minoxidil Solutions for the Treatment of Androgenetic Alopecia: Stability Studies and Incorporation Tests of Active Pharmaceutical Ingredients in Aloplus Total Base

February 2024 in “PubMed”

The new minoxidil lotion using Aloplus Total is stable and can be mixed with other ingredients for treating hair loss.

research Use of Topical Minoxidil, 17α-Estradiol, and Hydrocortisone Butyrate in Frontal Fibrosing Alopecia

1 citations, May 2014 in “European Journal of Inflammation”

A lotion with minoxidil, hydrocortisone butyrate, and 17a-estradiol can improve or stabilize Frontal Fibrosing Alopecia in some cases, but there's no universally-accepted treatment yet.

research New Topical Treatment for Psoriasis

July 2023 in “Journal of exploratory research in pharmacology”

A new psoriasis lotion called "Psorisbye" improved symptoms in a patient within one week.

research Peculiar Hypertrichosis in a Patient Affected by Frontal Fibrosing Alopecia with Pseudo Fringe Sign

2 citations, July 2020 in “Giornale italiano di dermatologia e venereologia”

A woman with frontal fibrosing alopecia experienced unusual hair growth after using a specific topical lotion.

research Therapy Experience in Alopecia After COVID-19

1 citations, August 2022 in “Медицинский совет”

The treatment with an oral drug and topical lotion is effective and well-tolerated for hair loss after COVID-19.

Placebo-Controlled Dose-Effect Studies with Topical Minoxidil 2% or 5% in Male-Patterned Hair Loss Treated with Oral Finasteride Employing an Analytical and Exhaustive Study Protocol

research Placebo-Controlled Dose-Effect Studies with Topical Minoxidil 2% or 5% in Male-Patterned Hair Loss Treated with Oral Finasteride Employing an Analytical and Exhaustive Study Protocol

5 citations, January 2020 in “Skin Research and Technology”

Minoxidil 5% works better than 2% for hair growth in male-patterned hair loss.

Topically Applied Magnetized Saline Water Activates Autophagy in the Scalp and Increases Hair Count and Hair Mass Index in Men With Mild-to-Moderate Androgenetic Alopecia

research Topically Applied Magnetized Saline Water Activates Autophagy in the Scalp and Increases Hair Count and Hair Mass Index in Men With Mild-to-Moderate Androgenetic Alopecia

November 2023 in “Cureus”

Magnetized saline water lotion increased hair growth in men with hair loss.

research Diffused Alopecia Followed by Severe Acute Respiratory Syndrome Coronavirus-2 Infection

April 2021 in “Libyan journal of medical sciences”

A woman's hair loss improved with treatment after a COVID-19 infection.

research Prevention and Treatment of Chemotherapy-Induced Alopecia: What Is Available and What Is Coming?

4 citations, March 2023 in “Current Oncology”

Scalp cooling is the only FDA-approved method to prevent hair loss from chemotherapy, but other treatments like minoxidil and PRP are being tested.

research Minoxidil

September 2010 in “Reactions Weekly”

A woman was allergic to 5% minoxidil, with stronger reactions to higher concentrations.

research Six-Month Prospective Study on the Effects of a Topical Product in Lotion and Shampoo Form Based on Low Molecular Weight Synthetic Thymus Peptides in Chronic Telogen Effluvium and Early Female Androgenetic Alopecia

September 2009

research Therapeutic Implications of Topical Cetirizine 1% in Treatment of Male Androgenetic Alopecia: A Case-Controlled Study

5 citations, January 2021 in “Journal of Cosmetic Dermatology”

Topical cetirizine 1% promotes hair growth in male androgenetic alopecia patients.

research A Preliminary Study on Topical Cetirizine in the Therapeutic Management of Androgenetic Alopecia

21 citations, June 2017 in “Journal of Dermatological Treatment”

Topical cetirizine improves hair density and thickness in androgenetic alopecia, but more research is needed.

research Comparison of Microneedling With Platelet Rich Plasma Versus Minoxidil (5%) Plus Finasteride (0.1%) Topical Therapy in Androgenetic Alopecia: A Randomised Clinical Study

January 2023 in “Journal of Clinical and Diagnostic Research”

Microneedling with PRP is as effective and safe as minoxidil+finasteride for treating hair loss.

research A Review of Diagnosis and Treatment of Acne in Adult Female Patients

116 citations, December 2017 in “International Journal of Women's Dermatology”

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

research A Multimodal Hair-Loss Treatment Strategy Using a New Topical Phytoactive Formulation: A Report of Five Cases

2 citations, February 2021 in “Case reports in dermatological medicine”

The new topical botanical formulation significantly regrew hair in all five patients without side effects.

research The Effect of a Food Supplement and a Hair Lotion on the Progression of Androgenetic Alopecia

2 citations, January 2019 in “Journal of Cosmetics, Dermatological Sciences and Applications”

The supplement and lotion significantly reduced hair loss and improved hair health.

research Androgenetic Alopecia: An Evidence-Based Treatment Update

151 citations, May 2014 in “American Journal of Clinical Dermatology”

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

research Safety of Dermatologic Medications in Pregnancy and Lactation

73 citations, March 2014 in “Journal of The American Academy of Dermatology”

Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.

research Alopecia

January 1991 in “Journal of Pediatric Health Care”

Hair loss in children can be caused by fungal infections, trauma, autoimmune disorders, or stress, and treatments vary depending on the cause.

research Common Dermatologic Conditions

14 citations, April 2014 in “Medical Clinics of North America”

The document concludes that quick referral and appropriate treatments are crucial for managing common skin conditions and preventing permanent damage.

research Telogen Effluvium Caused by Magnesium Valproate and Lamotrigine

16 citations, October 2004 in “Acta dermato-venereologica”

Two people lost a lot of hair because of epilepsy drugs, but their hair grew back after changing medication.

research Lamellar Ichthyosis with Pseudoexon Activation in the Transglutaminase 1 Gene

10 citations, March 2015 in “Journal of dermatology”

The boy's severe skin disorder is caused by two new mutations in his TGM1 gene.