August 2017 in “Journal of the Dermatology Nurses' Association” This article reviews the usage, efficacy, side effects, and alternatives of topical bimatoprost 0.03% for dermatological applications but does not present new clinical findings.
January 2023 in “International Journal of Pharmacy and Pharmaceutical Science” In this observational study conducted in Bengaluru, India, among 272 dermatology patients, the authors reported that dermatitis was the most common condition treated with corticosteroids, with a preference for topical applications; desonide was the most frequently prescribed drug.
August 2021 in “Annales pharmaceutiques françaises” This study used computer simulations to evaluate the absorption of oral and topical finasteride for treating androgenetic alopecia, finding that topical applications resulted in lower plasma concentrations, suggesting potential viability as a treatment option.
This case report discusses a patient with female androgenetic alopecia and chronic telogen effluvium, emphasizing the importance of follicular unclogging to enhance treatment effectiveness, combining deep cleaning, caffeine application, physical stimulation, and lifestyle changes as an individualized, effective alternative to oral medications.
September 2023 in “Cureus” This study reviewed early research on topical finasteride for androgenetic alopecia, finding it appears safe and promising, though further investigation is needed to determine optimal dosing, frequency, and potential applications for other types of alopecia.
51 citations
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October 2024 in “Pharmaceutics” This review highlights the potential of permeation enhancers to improve the delivery of active ingredients across the skin, optimizing therapeutic outcomes despite challenges posed by individual variability and environmental factors, according to the authors' analysis of current understanding and applications in skincare and transdermal therapies.
1 citations
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January 2024 in “Journal of Feline Medicine and Surgery Open Reports” In this study, the researchers describe a case of feline demodicosis that presented with dermatological lesions but lacked the typical signs of pruritus or overgrooming, and they report successful off-label treatment using a single spot-on application of fluralaner.
1 citations
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January 2017 in “Journal of Clinical Trials & Patenting” This study assessed the safety and efficacy of Romantaque lotion for unwanted hair growth and found statistically significant hair growth inhibition with no adverse effects in 30 volunteers after repeated applications over one year.
June 2026 in “International Journal of Advanced Multidisciplinary Research and Studies” This study highlights the potential of a ketoconazole antifungal hair spray as an innovative and effective topical method for treating tinea capitis, offering benefits such as easy application, improved drug penetration, and reduced systemic exposure compared to conventional treatments.
In this study, chitosan hydrogels and delivery systems showed promise in supporting skin recovery post-laser procedures, enhancing topical treatments for acne and melasma, and improving hair density in scalp applications, but limited study sizes and formulation variability restrict generalizability.
This study developed consensus guidelines for the use of low-dose oral and topical minoxidil in male and female pattern hair loss, recommending specific doses, monitoring procedures, and timing of application around hair transplant surgeries.
This study developed consensus guidelines for using low-dose oral and topical minoxidil in patients undergoing hair transplant surgery for pattern hair loss, recommending dosing adjustments, monitoring protocols, and timing for post-surgery application.
February 2024 in “Archives of Dermatological Research” In this study conducted at the University of Michigan Alopecia Clinic, survey respondents demonstrated high awareness (97.9%) of topical minoxidil for hair loss, with medical professionals being the most influential information source (34%). Concerns about usage included continuous application (46.8%) and skepticism about regrowth (29.8%).
December 2023 in “International Journal of Advanced Research in Science, Communication and Technology” This study developed and validated a precise and rapid HPLC method to simultaneously determine Minoxidil and Finasteride in pharmaceuticals, demonstrating successful application for routine quality control without interference from excipients.
August 2023 in “European journal of dermatology/EJD. European journal of dermatology” This study reported that therapeutic make-up significantly improves the long-term quality of life for patients with facial dermatoses, showing a sustained benefit one year after application, particularly in younger patients.
April 2024 in “The Egyptian Journal of Hospital Medicine” This review highlights that microneedling is an effective and flexible technique for enhancing transdermal drug delivery, with numerous applications in both cosmetic and therapeutic dermatological treatments. The researchers note that further advancements are likely to increase its efficacy and safety.
February 2023 in “Seven Editora eBooks” This study aims to compare the differences in adverse reactions and efficacy between topical and oral use of minoxidil for hair growth, with a focus on newer, lower-dose oral applications originally used for hypertension.
February 2021 in “Aesthetic Cosmetology and Medicine” This study suggests that glycosaminoglycans, like hyaluronic acid obtained biotechnologically, are safe for topical cosmetic use, enhancing skin and hair conditions by supporting cell renewal, stimulating hair growth, and aiding in the treatment of scalp issues such as seborrhea and androgenetic alopecia.
3 citations
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January 2023 in “International Journal of Cosmetic Science” This review discusses recent patents on the cosmetic use of coffee and its by-products, highlighting their potential as promising topical formulation ingredients with skin health benefits.
May 2026 in “Therapeutic Delivery” This study found that applying a dutasteride-loaded liposome formulation to damp rat skin nearly doubled the drug's follicular accumulation compared to dry skin, suggesting scalp hydration status may significantly impact the drug's topical delivery, especially in follicle-rich areas.
February 2025 in “Prospects in Pharmaceutical Sciences” This source reports that clascoterone cream, a topical androgen receptor inhibitor, has shown effectiveness in treating facial acne vulgaris in patients 12 and older, with clinical trials indicating a favorable safety profile compared to systemic treatments, and potential for broader dermatological applications.
37 citations
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November 1995 in “Journal of Investigative Dermatology” This study found that topical finasteride and flutamide both significantly reduced sebaceous gland growth and decreased prostatic weights in hamsters, indicating systemic effects despite local application.
April 2023 in “UNESP Institutional Repository (São Paulo State University)” In this study, oral minoxidil at 5 mg/day improved hair density comparably to topical minoxidil 5% in men with androgenetic alopecia over 24 weeks, offering a viable alternative for those intolerant to topical application.
April 2016 in “Journal of Investigative Dermatology” This study found a perfect correlation between laser Doppler velocimetry measurements of scalp blood perfusion after minoxidil application and sulfotransferase enzyme activity in hair follicles, indicating a potential non-invasive test to predict minoxidil response in female pattern hair loss.
5 citations
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January 2020 in “Veterinary Dermatology” In this study, researchers evaluated the antifungal effectiveness of topical products on infected kitten hair, finding most were effective after one application, with enilconazole and lime sulfur showing residual activity; however, 0.15% ketoconazole with chlorhexidine had no such lasting effect.
94 citations
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May 2011 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” This study found that hair follicles contribute significantly to caffeine absorption shortly after topical application, with a faster absorption rate compared to the stratum corneum.
5 citations
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April 2022 in “IntechOpen eBooks” This source describes the potential benefits of a nanoemulgel delivery system for enhancing the use of lipophilic drugs, improving patient compliance, and expanding treatment options for various conditions, including acne, arthritis-related inflammation, and Parkinson's disease, while also offering sunburn protection in cosmetic applications.
1 citations
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January 2010 This study found that using minoxidil 2% as a mesotherapy injection showed more significant improvement in treating androgenetic alopecia in female patients than topical application.
September 2025 in “Pharmaceutics” In this study, quercetin nanocrystals stabilized with glycyrrhizic acid were developed as a new treatment strategy for androgenetic alopecia, which significantly reduced DHT levels and improved hair regrowth in a mouse model, indicating synergistic potential for clinical application.
February 2017 in “Cancer Research” In this study involving women undergoing taxane-based chemotherapy, a twice-daily topical application of BPM31543 was well-tolerated and showed potential in reducing severe hair loss, prompting further investigation at higher doses.