January 2025 in “Indian Journal of Small Ruminants (The)” In this case study of a Beetal doe with severe skin lesions, the researchers diagnosed concurrent psoroptic mange and malasseziosis, and reported successful treatment with a combination of Ivermectin, antibiotics, and topical applications, leading to reduced skin lesions and new hair growth.
October 2024 in “University of Thi-Qar Journal of Medicine” This study found that PRP therapy, topical treatments, and pharmacological interventions were effective in reducing hair loss among adults in Sulaimani Province.
July 2022 in “Revista Científica de Estética e Cosmetologia” This integrative literature review reported that various topical and professional treatments for androgenetic alopecia generally provided satisfactory results for patients seeking to address hair loss.
This review identifies headache, hypertrichosis, and allergy as potential side effects of Minoxidil treatment for hair loss, based on only two studies that met inclusion criteria.
December 2008 in “Enzyme and Microbial Technology” New patents include innovations in skin and hair care, disease treatment, plant stress tolerance, and protein purification.
This study developed a novel protocol that demonstrated improved localized delivery of minoxidil to eyebrow application sites with minimal runoff, compared to a control formulation.
October 2020 in “Journal of Pharmaceutical Sciences” This study found that using gallate-containing formulations like EGCG or tannic acid increased the solubility and controlled release of finasteride in microspheres, enhancing its dermal penetration in pig skin by 10 to 50 times compared to a control.
January 2010 in “West China Journal of Pharmaceutical Sciences” The study found that high-dose intragastric administration of Pterocarpus indcus Willd extracts reduced hair loss and increased hair follicles in a rat model of androgenetic alopecia, but topical application did not show significant effects.
13 citations
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November 1996 in “International Journal of Dermatology” This article reviews the role of liposomes in dermatology and does not report new clinical results.
12 citations
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May 2020 in “Actas Dermo-Sifiliográficas” This article discusses emerging therapies for androgenetic alopecia, highlighting the use of intradermal dutasteride, but it reports no new clinical findings.
August 2024 in “Bioorganic Chemistry” This study found that oral administration of cedrol, a component of ginger, improved hair regeneration and reduced hair follicle damage in cyclophosphamide-induced alopecia areata in mice more effectively than external administration, by enhancing cytokine expression and modulating key signaling pathways.
June 2023 in “Brazilian Journal of Health Review” This review discusses the characteristics, causes, diagnosis, and treatment options for androgenetic alopecia and emphasizes the importance of managing expectations due to the variability in therapeutic outcomes.
September 2020 in “Farmacja Polska” This review discusses various applications of foam systems in drug form technology, highlighting their potential to enhance drug solubility and release modifications, but reports no new clinical results.
70 citations
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February 2015 in “Expert Opinion on Drug Discovery” This review discusses current knowledge on the biological mechanisms of different types of alopecia but reports no new clinical findings; the authors highlight future research directions, especially regarding epidermal stem cells and immune pathways.
48 citations
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June 2013 in “Journal of Dermatological Science” This study found that valproic acid promoted human hair growth by increasing β-catenin levels, suggesting it may be a potential therapeutic option for alopecia.
5 citations
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April 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)” In this review, researchers noted that liposomes, due to their ability to stabilize and target drugs, are effective carriers for treating various dermatological conditions such as acne and psoriasis when applied topically.
September 1995 in “American Journal of Contact Dermatitis” Antiyeast treatments work better for seborrheic dermatitis than steroids, and other findings include increased skin bacteria under plastic wrap, a nasal cell defect in Staphylococcus aureus carriers, quick resolution of certain skin reactions, high rubber latex allergy in spina bifida patients, and glyceryl monopentadecanoate's effectiveness for male hair loss.
April 2026 in “Brazilian Journal of Hair Health” In this case report, a 36-year-old male with androgenetic alopecia showed clinically visible improvement in hair density after three monthly sessions of microneedling combined with exosome application, although the authors note that further studies are needed to verify these findings.
28 citations
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May 1994 in “The Journal of Urology” This study found that topical application of 2% minoxidil solution was not effective in improving erectile dysfunction in the majority of participants.
18 citations
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May 2015 in “Australasian Journal of Dermatology” This study found that topical application of Serenoa repens extract increased hair count in men with androgenetic alopecia, suggesting it could be an alternative for those unable to use standard medications.
11 citations
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October 2017 in “Journal of Investigative Dermatology” This study found that topical application of mitochondrial electron transport chain inhibitors stimulated hair follicle stem cell activation and hair regrowth in aged mice by promoting lactate production.
69 citations
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February 1987 in “Archives of Dermatology” This case report describes the topical application of cyclosporine in a man with alopecia universalis, which showed hair regrowth after 10 months of daily use, except where limited by a congenital nevus.
May 2019 in “Journal of clinical oncology” This Phase 1 study reported that topical application of BPM31543 was safe and well-tolerated in patients receiving taxane-based chemotherapy, with some experiencing less than 50% hair loss, suggesting potential efficacy in reducing chemotherapy-induced alopecia, although no maximum tolerated dose was identified.
51 citations
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March 1987 in “Journal of The American Academy of Dermatology” This study found that twice-daily application of 3% topical minoxidil maintained a higher nonvellus hair count compared to once-daily application over 2 years and 9 months in men with male pattern baldness.
5 citations
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March 2024 in “Acta Scientiarum Polonorum Technologia Alimentaria” This study synthesized existing research on 11 tropical seed varieties, underscoring their potential in food, pharmaceutical, and agricultural industries due to their phytochemicals and nutrients, such as phenolics and vitamins, which could reduce waste and support sustainable practices.
12 citations
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December 2009 in “Amino Acids” In this study, topical application of α-methylspermidine during the telogen phase in mice induced hair growth by increasing the polyamine pool and mimicking the anagen phase's characteristics.
5 citations
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August 2025 in “Drug Delivery and Translational Research” This review discusses lipid-polymer hybrid nanoparticles for dermatological applications, outlining their structural and formulation advancements, but reports no new clinical results and calls for further research on their therapeutic potential.
3 citations
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June 2021 in “PLOS ONE” This study found that topical application of the BRAF inhibitor vemurafenib improved wound healing and promoted hair follicle regeneration in a diabetic murine model.
1 citations
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January 2023 in “European Journal of Research in Dentistry” This study found that topical application of tideglusib in a bacterial cellulose-based hydrogel showed positive effects on the healing of palatal wounds in rats.
1 citations
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April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that topical application of the HDAC1/3 inhibitor Vorinostat promoted hair regrowth in a mouse model of alopecia areata and influenced the hair cycle in normal mice.