January 2016 in “SpringerBriefs in bioengineering” Genetic defects and UV radiation cause skin damage and aging.
276 citations,
December 2017 in “Journal of Dermatological Science” The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.
188 citations,
October 2012 in “The AAPS Journal” The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.
119 citations,
December 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Nanoparticles can deliver vaccines through hair follicles, triggering immune responses and providing protection.
83 citations,
January 2015 in “World Journal of Stem Cells” Hair follicle regeneration needs special conditions and young cells.
69 citations,
January 2002 in “Journal of biomedical optics” Dyes can penetrate human skin and hair follicles up to 1.2 mm deep and the sebaceous gland can store dye; Indocyanine Green lotion was made for safe dyeing and monitoring.
65 citations,
March 2018 in “Journal of Dermatological Science” Skin problems can be caused or worsened by physical forces and pressure on the skin.
21 citations,
November 2012 in “Plastic and Reconstructive Surgery” Both genetic and lifestyle factors significantly affect female hair loss.
16 citations,
December 2006 in “Expert Review of Dermatology” Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.
14 citations,
November 2019 in “Materials” Diamond nanoparticles can penetrate skin and reach hair follicles, useful for imaging applications.
13 citations,
January 2021 in “Scientific Reports” Pannexin 3 helps skin and hair growth by controlling a protein called Epiprofin.
8 citations,
July 2008 in “Facial Plastic Surgery Clinics of North America” More men are getting non-surgical cosmetic treatments due to increased income and social acceptance, with less invasive options being preferred.
5 citations,
December 2020 in “Experimental dermatology” A specific type of skin cell creates an opening for hair to grow out, and problems with this process can lead to skin conditions.
1 citations,
September 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin organoids from stem cells can help study and treat skin issues but face some challenges.
132 citations,
January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
131 citations,
March 2004 in “The American journal of pathology” Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.
56 citations,
June 2015 in “Nature Protocols” Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.
44 citations,
October 2019 in “International Journal of Molecular Sciences” Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.
22 citations,
November 2012 in “Journal of cosmetic dermatology” Stem cells can rejuvenate skin, restore hair, and aid in wound healing.
21 citations,
February 2015 in “Journal of Feline Medicine and Surgery” Negative pressure wound therapy is effective for skin grafts in cats.
16 citations,
December 2020 in “PloS one” Researchers found WNT10A to be a key gene in developing goat hair follicles.
16 citations,
June 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” The enzyme DHHC13 is essential for healthy hair and skin, and its deficiency leads to hair loss and skin problems.
9 citations,
June 2023 in “Cells” Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
9 citations,
August 2021 in “International journal of molecular sciences” PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.
7 citations,
June 2022 in “Frontiers in Medicine” ADSC-derived extracellular vesicles show promise for skin and hair regeneration and wound healing.
6 citations,
March 2022 in “International journal of molecular sciences” Natural skincare products may help reduce sun damage and support the skin's daily cycle.
3 citations,
May 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin lesions in Carney Complex are caused by a gene change in some skin cells that leads to increased pigmentation and may lead to tumors.
April 2024 in “International journal of molecular sciences” Light-based treatment, Photobiomodulation, shows promise for non-invasive skin therapy with few side effects.
October 2023 in “Biomedical science and engineering” Innovative methods are reducing animal testing and improving biomedical research.
August 2023 in “International Journal of Molecular Sciences” Human skin xenografting could improve our understanding of skin development, renewal, and healing.