December 2023 in “Journal of Cosmetic Dermatology” This study found that baricitinib, taken for 24 weeks, significantly reduced alopecia severity in patients with moderate-to-severe alopecia areata, with 50% showing marked improvement and overall favorable safety and efficacy reported.
November 2023 in “Medical Immunology (Russia)” In this study, researchers found that children with alopecia areata exhibited immune system imbalances, including increased autoimmune and allergic markers and decreased phagocytic activity, along with a higher prevalence of autoimmune thyroiditis and allergic rhinitis compared to children without alopecia.
May 2022 in “Голова и шея.” This study found a direct correlation between chronic tonsillitis and increased NETosis activity in peripheral blood and palatine tonsil lacunae.
51 citations
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July 2003 in “Annals of the Rheumatic Diseases” This case study reports a successful use of co-trimoxazole in treating a 13-year-old girl with symptoms suggestive of autoimmune disorders and relapsing polychondritis.
32 citations
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July 2003 in “Annals of the Rheumatic Diseases” This case report describes the successful treatment of a 13-year-old girl's autoimmune symptoms with co-trimoxazole, an antibiotic with immunomodulatory properties.
8 citations
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July 2003 in “Annals of the Rheumatic Diseases” This case study describes the successful treatment of a 13-year-old girl with relapsing polychondritis and autoimmune symptoms using co-trimoxazole, highlighting its potential role in managing autoimmune diseases.
5 citations
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July 2003 in “Annals of the Rheumatic Diseases” In this case study, a 13-year-old girl with multiple autoimmune symptoms was successfully treated with the antibiotic and immunomodulatory drug co-trimoxazole.
August 2025 in “International Journal of Cancer” This study reported that postnatal environmental factors, such as childhood height and early hospitalization for immune-related diseases, were associated with an increased risk of testicular germ-cell tumor, with minimal observed variation between seminomas and non-seminomas.
In this case study, a 19-year-old woman with Henoch-Schönlein purpura, potentially triggered by hepatitis B vaccination, experienced improved symptoms after correcting low vitamin D levels and undergoing tonsillectomy, demonstrating these interventions may benefit similar patients.
April 2018 in “Journal of Investigative Dermatology” This study found that palmoplantar pustulosis patients exhibited oral dysbiosis, particularly among those with pustulotic arthro-osteosis, as compared to healthy controls.
April 2018 in “Journal of Investigative Dermatology” In this first-in-human study, BLZ-100, an intraoperative fluorescent imaging agent, was administered to 21 patients before skin cancer surgery and was found to be well tolerated without serious adverse effects, suggesting its potential to help distinguish cancerous from non-cancerous tissue based on fluorescence.
April 2018 in “Journal of Investigative Dermatology” This study found that high skin expression of amphiregulin in acute graft-versus-host disease was associated with severe disease grade, poor overall survival, and increased non-relapse mortality.
April 2018 in “Journal of Investigative Dermatology” In this study, researchers reported that IL-17C plays a key pro-inflammatory role in human skin diseases and may be a promising therapeutic target for inflammatory skin conditions.
April 2018 in “Journal of Investigative Dermatology” This study found that DC-HIL+ myeloid derived suppressor cells are increased in the blood and skin of patients with cutaneous lupus erythematosus and show immunosuppressive properties.
April 2018 in “Journal of Investigative Dermatology” This study found that 1550-nm Er:Glass fractional laser treatment significantly increased hair density and shaft diameter in patients with androgenetic alopecia, though the mechanism may not involve Wnt10A or IGF-1 expression.
19 citations
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January 2016 in “Annals of Dermatology” This study found that dutasteride 0.5 mg was generally well-tolerated and led to overall improvement in male patients aged 18 to 41 with androgenic alopecia in a Korean clinical practice setting.
8 citations
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August 1997 in “Australasian Journal of Dermatology” This review discusses the distinctive non-infective skin presentations of HIV infection from a dermatological perspective and reports no new clinical findings.
January 2024 in “Journal of Natural Remedies” This study found that the petroleum ether extract of Solanum nigrum may promote hair regrowth in testosterone-induced hair loss in rats, as indicated by increased follicle density and anagen/telogen ratio.
September 2009 in “Pediatric Dermatology” This meeting abstract volume for the Society for Pediatric Dermatology reports no new clinical results.
238 citations
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November 2016 in “Journal of The American Academy of Dermatology” In this study, tofacitinib was reported to improve scalp hair regrowth in patients with severe alopecia areata, alopecia totalis, and alopecia universalis, showing a higher response in alopecia areata.
128 citations
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January 2001 in “American Journal of Clinical Dermatology” This review provides an overview of scalp psoriasis treatments but presents no new clinical results; it highlights various options including coal tar, salicylic acid, corticosteroids, and vitamin D3 analogues.
74 citations
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September 1980 in “Medical Clinics of North America” This article discusses toxic epidermal necrolysis, highlighting its high mortality rate despite aggressive treatment, and notes controversy over using high-dose systemic corticosteroids as therapy.
66 citations
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December 2018 in “Dermatology” This study found that oral JAK inhibitors, ruxolitinib and tofacitinib, are effective and well-tolerated for treating severe alopecia areata, with a similar degree of hair regrowth and relapse rates, but ruxolitinib induced faster initial hair regrowth.
55 citations
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October 2019 in “Dermatology and therapy” This review found that JAK/STAT pathway inhibitors, such as tofacitinib and ruxolitinib, led to symptom improvement in all observed atopic dermatitis cases, but responses were mixed for vitiligo and alopecia areata, with a generally mild safety profile reported.
53 citations
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November 1992 in “Mayo Clinic Proceedings” This review discusses the cutaneous manifestations associated with HIV infection, highlighting that these skin conditions often present atypically and are more severe compared to those in non-HIV-infected individuals; it reports no new clinical findings.
40 citations
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November 2016 in “Molecules” This review discusses the historical and current use of ribosome-inactivating protein-expressing plants in traditional medicine across various cultures and regions, highlighting their role despite a lack of scientific validation.
35 citations
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January 2019 in “Clinics in Dermatology” This review discusses contemporary issues in syphilis diagnosis and management, emphasizing the importance of recognizing and addressing both biomedical and psychosocial aspects, but provides no new clinical results.
16 citations
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September 2015 in “Journal of Ethnopharmacology” This review examines the long-standing use of "Dictamnus" in traditional medicine, highlighting the promising potential of D. albus and D. hispanicus as herbal drug candidates, but presents no new experimental findings.
16 citations
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May 1998 in “International Journal of Dermatology” This study found that elevated serum cortisol levels and other immunological changes are significantly involved in the active phases of psoriasis eruptions.
15 citations
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September 2018 in “Indian Research Journal of Pharmacy and Science” This article reviews the historical and therapeutic aspects of aromatherapy, discussing its effects on psychological and physical well-being but providing no new clinical findings.