56 citations
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July 2004 in “Mechanisms of Development” Pax9 is crucial for proper tongue surface development and preventing skin-like changes.
In this case report, the researchers highlight a possible association between myotonic dystrophy type 1 and multiple tongue hemangiomas, and emphasize that patients with this condition can experience exacerbated respiratory muscle weakness and risk of respiratory failure even with epidural anesthesia.
April 2024 in “Acta scientific dental sciences” This case study describes a 45-year-old male with black hairy tongue who experienced complete resolution of tongue discoloration and improved halitosis after receiving treatment focused on enhanced oral hygiene, tongue brushing, and smoking cessation.
This abstract compiles a list of medical syndromes and conditions related to tongue abnormalities and other systemic features but reports no new research findings.
12 citations
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January 2005 in “Pediatric Dermatology” Fox Fordyce disease might be more common in prepubertal girls than thought and can be managed with treatment.
December 2023 in “JEADV Clinical Practice” In this report, a young Caucasian woman developed a hairy tongue as an unusual side effect during baricitinib therapy for severe alopecia areata, which was managed by daily toothbrush debridement.
18 citations
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December 2010 in “Transplantation Proceedings” This study reported that black hairy tongue can occur after allogeneic stem cell transplantation and may indicate cutaneous graft-versus-host disease, highlighting the need for histopathologic evaluation.
16 citations
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June 1992 in “Journal of Investigative Dermatology” 7 citations
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September 1962 in “Oral Surgery Oral Medicine Oral Pathology” This study reported that black hairy tongue was rapidly resolved with topical triamcinolone acetonide, suggesting further trials for its treatment are warranted.
September 2025 in “BioMed” In this case report and literature review, researchers observed that black hairy tongue syndrome can be improved by dietary restrictions and local care, identifying factors like antibiotics, malignancies, and certain medications as common triggers, with resolution achieved by eliminating these factors when possible.
This study purified trichohyalin protein from pig tongue epithelium, characterizing its unique properties and structure, which may facilitate future functional research.
November 2012 in “Actas Dermo-Sifiliográficas” An 86-year-old man had a rare tongue melanoma but refused treatment, showing the need for early cancer detection and treatment.
128 citations
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March 1989 in “Experimental Cell Research” Hoxc13 is important for hair and tongue development by controlling hair keratin genes.
September 2024 in “World Journal of Clinical Oncology” Chemotherapy with docetaxel and cisplatin can cause severe low potassium, requiring careful monitoring and treatment.
2 citations
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January 2018 in “Open journal of stomatology” This study found that trichohyalin is expressed in cancerous tongue epithelial cells, while plectin-1 expression may indicate malignancy.
1 citations
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October 2020 in “Egyptian Dental Journal /Egyptian Dental Journal” This study found that platelet-rich plasma treatment improved wound healing in both diabetic and non-diabetic rat tongue wounds, particularly when applied before injury.
January 2024 in “Journal of Hard Tissue Biology” In this study, researchers found that a high-fat diet in mice induced downregulation of certain Krtap genes in the tongue, which may be linked to structural issues or oral cancer risk, highlighting a potential connection between oral health and systemic diseases like metabolic syndrome.
27 citations
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July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” 4 citations
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September 2020 in “Open Access Macedonian Journal of Medical Sciences” This study concluded that a single injection of platelet-rich plasma can enhance wound healing in both diabetic and non-diabetic oral mucosal tissues in rats.
2 citations
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March 2019 in “Journal of Histochemistry and Cytochemistry” This study found that NNAT is localized in both undifferentiated and differentiated cells across various rat tissues and has cell-specific intracellular localization, suggesting distinct functional roles.
75 citations
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October 1999 in “Differentiation” This study suggests that mouse keratin 6 isoforms, K6a and K6b, have overlapping but distinct expression profiles, differing notably in their expression in suprabasal cells and response to phorbol esters.
187 citations
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May 1988 in “Differentiation” This study found that trichocytic cytokeratins, typically found in hair, are also present in nails, filiform papillae of the tongue, and the epithelial reticulum of the thymus.
48 citations
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May 1991 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that trichohyalin, a protein previously thought to be restricted to hair and tongue, is also present in isolated cells within the granular layer and stratum corneum of normal human epidermis.
27 citations
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October 2017 in “British Journal of Dermatology” Patients with GATA2 deficiency show early skin symptoms that help diagnose the condition.
4 citations
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January 1970 in “Bangladesh Journal of Veterinary Medicine” This study found that 88.89% of examined domestic and stray cats in Mymensingh district, Bangladesh, were infested with arthropods, notably Ctenocephalides felis felis, with higher prevalence in females and in summer for certain infections.
June 2022 in “Pham Ngoc Thach Journal of Medicine and Pharmacy” This study identified key natural compounds such as polyphenols and flavonoids in tongue fern and established optimal extraction conditions using methanol.
September 2015 in “International Journal of Dermatology” In Ethiopia, this study found that certain skin and mucous membrane disorders, particularly oral conditions, were statistically related to HIV infection and may assist in early detection of the disease.
25 citations
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January 2005 in “Pediatric Dermatology” This article discusses the use of methotrexate for treating generalized pustular psoriasis in a 2-year-old child, providing a specific case study but reporting no new clinical results.
In this study, researchers developed an AI-powered platform called VitaDetect, which screens for vitamin deficiencies using image analysis of nails, tongue, and skin, aiming to provide an accessible and early-stage detection tool in resource-limited settings.
January 2016 in “Türkiye klinikleri tıp bilimleri dergisi” About 38% of patients at a dermatology clinic had oral lesions, with coated tongue, fissured tongue, and Fordyce granules being most common.