February 2014 in “PubMed” This study found that Lycopersicon esculentum extracts applied to mice promoted hair growth similarly to minoxidil and increased growth factor expression, suggesting potential in hair loss treatments without skin irritation.
1 citations
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October 2018 in “International research journal of pharmacy” This study found that ethanol extract and n-hexane fraction of rampai leaves may stimulate hair growth in rabbits, showing potential as an anti-alopecia treatment.
This study found that PLX, a mixture of tomato extract and chitooligosaccharide, may reduce prostate weight in testosterone-induced BPH in rats, suggesting it could act as a 5α-reductase inhibitor.
January 2022 in “International Journal of Nutrology” This review discusses the potential role of nutritional supplements, like lycopene and tranexamic acid, in managing melasma during the COVID-19 pandemic but reports no new clinical outcomes.
9 citations
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January 2010 This study reports that a 100% herbal hair dye composed primarily of Cymphomandra betacea, Tagetes erecta, and Aloe vera gel provides permanent hair color without causing hair damage, loss, or skin irritation compared to synthetic dyes.
19 citations
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August 2010 in “Journal der Deutschen Dermatologischen Gesellschaft” This review discusses plant extracts for dermatological use, highlighting evidence that some can reduce edema in chronic venous insufficiency or help treat actinic keratoses, but it reports no new clinical results.
March 2024 in “Journal of Society of Cosmetic Chemists of Japan” In this study, a medicated hair growth tonic containing RJ extract increased hair counts, the proportion of anagen phase hairs, and scalp moisture in human trials, although the specific role of RJ in hair growth remains unclear due to other active ingredients.
November 2024 in “International Journal of Pharmaceutical Sciences Review and Research” This study evaluated herbal hair gels made with extracts of flax seed and curry leaves, finding that the formulations offered good texture, stability, and sensory appeal while promoting healthy hair and scalp without irritation, making them suitable for regular use.
December 2022 in “Proceeding Bengkulu International Conference on Health” This study concluded that a 5% concentration of celery extract in hair gel provided the best preparation characteristics, including standard parameters for organoleptic properties and spreadability.
20 citations
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January 2017 in “Nutrition Research and Practice” In this study, corn silk extract treatment improved symptoms of testosterone-induced BPH by reducing specific mRNA expression and decreasing levels of 5α-R2, DHT, and PSA.
19 citations
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April 2024 in “Journal of Umm Al-Qura University for Applied Sciences” This review explores the diverse roles of rosemary, covering its nutritional and medicinal uses, cosmetic and pharmaceutical applications, and evaluates various extraction methods, with a focus on sustainable practices and commercial prospects.
12 citations
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September 2014 in “Journal of Food Science and Nutrition” This study suggests that Platycarya strobilacea extract promotes hair growth in mice by enhancing stem cell factor expression, reducing mast cell numbers, and increasing cytokines associated with hair growth.
12 citations
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April 2023 in “Nano Biomedicine and Engineering” This study synthesized silver nanoparticles using an Artocarpus heterophyllus leaf extract and found that these nanoparticles, with a size of 100–110 nm, displayed effective antioxidant, antibacterial, and antifungal activities in vitro.
6 citations
,
April 2021 in “Scientific Reports” This study found that Phytochrome A is crucial for regulating central metabolism and the transition to mature seedling proteomes in tomato seedlings grown under far-red light.
11 citations
,
July 2021 in “Physiologia Plantarum” In this study, the gene SlPHL1 was identified as a transcription factor in tomatoes that enhances phosphate starvation responses by upregulating specific genes.
26 citations
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October 2017 in “Scientific reports” This study found that a bacterial endophyte from Zea nicaraguensis effectively targets and colonizes plant root hair cells, promoting growth and solubilizing insoluble phosphorus for nutrient uptake.
May 2024 in “Molecules/Molecules online/Molecules annual” This narrative review reports that well-selected plant extracts and their active compounds may improve hair health by promoting hair growth and preventing hair loss, potentially aiding in developing targeted therapies for alopecia.
1 citations
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February 2023 in “Plants” This study reported that rice bran oil from the Thai rice variety BB4CMU showed potential in promoting melanin production and inhibiting steroid 5α-reductase, suggesting a natural option for hair revitalization.
1 citations
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January 2013 in “Springer eBooks” Cosmeceuticals may benefit skin health but need more research for efficacy and safety confirmation.
March 2025 in “Formosa Journal of Sustainable Research” In this study involving male mice, Mangkokan leaf extract (Polyscias scutellaria) at a 7% concentration was found to heal incision wounds faster compared to 3% and 5% concentrations.
67 citations
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February 2015 in “Life Sciences” This review discusses phytotherapy options for managing benign prostatic hyperplasia, noting some herbal agents show promise in trials for mild-moderate symptoms but more evidence is needed for others.
3 citations
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January 2014 in “Arhiv za farmaciju” This article discusses the role and potential of plant stem cell extracts in cosmetics for their antioxidant and protective effects on skin cells, reporting no new clinical results; the authors highlight ecological and sustainable production methods.
124 citations
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June 2020 in “Cell Stem Cell” This study found that in mice, dermal adipocytes initiate inflammation and aid repair after skin injury by releasing lipids, suggesting a role in managing inflammatory diseases and impaired wound healing.
95 citations
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February 2018 in “Dermatology and Therapy” This review discusses the role of nutraceuticals in combating skin aging but reports no new clinical results, focusing on their mechanisms of action and potential effectiveness for dermatologists.
14 citations
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October 2000 in “Genomics” This study demonstrated that dermal papilla cells are molecularly distinct from fibroblasts and identified many novel molecules, including a new member of the CTGF protein family.
3 citations
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January 2023 in “Biodiversitas Journal of Biological Diversity” This study found that endophytic bacteria isolated from Leea indica leaves showed high antioxidant activity, suggesting they could be a novel source of natural antioxidants.
1 citations
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October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study demonstrated that intraoperative bioprinting using a bioink with human adipose-derived extracellular matrix and stem cells achieved successful reconstruction of full-thickness craniomaxillofacial skin defects in rats, promoting wound closure, adipogenesis, and hair follicle-like structure formation within two weeks.
July 2026 in “Pharmaceuticals” This review highlights significant research trends and challenges in utilizing plant-derived extracellular vesicles for drug delivery and biomedical applications, emphasizing the need for standardized protocols and advanced purification technologies.
August 2020 in “Research Square (Research Square)” This study found that nanovesicles derived from ReNcell VM cells promoted hair growth in mice by activating the Wnt/β-catenin signaling pathway, suggesting they may serve as an alternative to extracellular vesicles for hair growth therapy.
115 citations
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February 2016 in “Nature Communications” The authors concluded that the dermal response to epidermal Wnt/β-catenin signaling depends on distinct fibroblast lineages, with each responding to different paracrine signals such as Hedgehog and TGF-β.