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Retinoids are effective for skin conditions like severe acne and psoriasis but must be used with caution due to potential side effects and risks during pregnancy.

Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.

Spin traps like PBN could protect skin from pollution and sunlight in cosmetics but need more research for safe use.

Puberty often causes skin issues like acne and excessive sweating, and treatments require patience as results may vary.

Polyphenols may help treat skin conditions like warts, hair loss, acne, and dark spots, but more research is needed.

Hair graying is influenced by factors like nerves, fat cells, and immune cells, not just hair follicles.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Sebaceous glands are involved in various skin disorders, some treatable with medications like finasteride and minoxidil.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.

Hormonal therapy is effective for treating acne in adult women, especially with signs of high androgen levels.

Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.

Polymeric nanoparticles show promise for treating skin diseases.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

Clascoterone is a new, effective, and safe acne treatment without systemic side effects.

A specific DNA sequence caused hair loss in male mice by activating immune cells and increasing a certain immune signal.

Certain gene mutations can weaken the skin barrier and, when combined with environmental factors, lead to eczema and severe itching.

Inflammasome proteins can indicate the severity and treatment response of various diseases and injuries.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.