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Two new compounds were found that could promote hair growth as well or better than minoxidil.

This review discusses the growing use of scalp hair for elemental analysis in various fields and highlights advancements in analysis techniques, including the future potential of laser ablation ICP-MS, but reports no new clinical results.

This study concludes that phospholipid–polymer hybrid nanoparticles may be an effective delivery system for quercetin in treating androgenic alopecia by improving hair regrowth and preventing hair follicle cell apoptosis in rat models.

The authors reviewed the mechanisms behind Kennedy's disease, noting advances in therapeutic strategies such as androgen deprivation and gene silencing that may soon expand treatment options for this incurable neuromuscular condition.

This study found that dihydrotestosterone (DHT) suppresses prostaglandin E2 and TGF-β induced IGF-I gene promoter activity in osteoblasts, suggesting complex interactions among bone growth regulators and potential complications from anabolic steroid use.

This review highlights that clascoterone, a newly FDA-approved topical androgen antagonist, effectively reduces both non-inflammatory and inflammatory acne lesions with no systemic effects, making it a promising new option for acne treatment in both male and female patients.

The study reported that reducing finasteride particle size significantly improved its cellular permeation through prostate epithelial cells, though it had a lesser impact on systemic pharmacokinetics and tissue distribution in rats.

This study found that androgens downregulate BMP2 in dermal papilla cells, inhibiting hair follicle stem cell differentiation, while BMP2 addition may restore hair lineage differentiation through the Wnt/β-catenin pathway.

This study found that biotransformation of finasteride by Aspergillus niger produced two metabolites with different levels of lipoxygenase inhibition, suggesting potential for developing more potent derivatives.

This study found that vitamin D regulates cholesterol metabolism and may influence prostate cancer development through mechanisms affecting prostate cell growth and sex hormone metabolism.

This study found that flutamide was more effective than spironolactone in reducing symptoms of hirsutism and related conditions in premenopausal women, with fewer discontinuations due to side effects.

In this study, higher expression levels of aromatase and steroidogenic acute regulatory protein were correlated with increased estrogen synthesis and fewer hair follicles in human skin, suggesting a link to elastic fiber formation and hair growth.

In this study, the combination of SCF and ET-1 was found to significantly enhance skin pigmentation and melanin content in human skin xenografts on SCID mice compared to either treatment alone.

This study found that local androgen biosynthesis and metabolism in human sebaceous glands play a crucial role in sebum synthesis and secretion.

Minoxidil can lower blood pressure in some people.

This study found that in Japanese, German, and American females, changes in hair lipid patterns with age may reflect alterations in sebum excretion and affect hair texture.

This study identified two high sulfur protein genes, B2E and B2F, in rats, which are expressed in hair cortical cells during anagen and contribute to hair fiber production.

The study observed that mRAGE expression is prevalent in keratinocytes of the healthy human epidermis and may regulate inflammation and apoptosis to maintain skin homeostasis rather than responding to aging processes.

This study found that trans-3,4'-Dimethyl-3-hydroxyflavanone reduces active TGF-beta2 levels in human keratinocytes, suggesting it may enhance hair growth by suppressing the TGF-beta2 activation pathway.

In this study, the safety of finasteride in rats varied depending on dosing time, while its effectiveness on prostate weight reduction remained consistent.

In this study, otitis externa in toy poodles and miniature dachshunds was successfully treated using a video otoscope alongside systemic antibiotics and antifungals, with all dogs recovering fully.

This study used rapid-freezing immunocytochemistry to successfully map the ultrastructural localization of hair keratins in human scalp hair, primarily finding them in macrofibrils in the cortex and endocuticle.

This study found that skin surface lipids contain measurable mRNAs, providing a non-invasive way to study skin diseases, with specific gene expression changes observed in atopic dermatitis patients.

Forensic medicine is crucial for justice and needs continuous innovation and technology integration.

This case report describes a hybrid cyst in a Sprague-Dawley rat, showing both infundibular and matrical differentiation similar to different parts of normal hair follicles.

This congress summary highlights the COMEF 2023 event, which focused on medical ethics, education, and health through discussions with the theme "Learn, practice, excel," but reports no new research findings.

This study in mice found that a zinc-deficient diet suppressed body weight gain and increased kidney and cecum tissue weight without decreasing serum alkaline phosphatase activity. Additionally, zinc deficiency caused alopecia and intestinal changes in C57BL/6J mice, potentially affecting nutritional status.

In this study, the MPV/PC ratio was identified as a potential tool for assessing disease activity in alopecia areata, with higher ratios in active and severe cases compared to inactive and mild/moderate ones.

This article discusses the diagnosis and management of allergic dermatoses in dogs, focusing on clinical diagnosis, complementary tests, and various treatment strategies, but it reports no new results.

In this study, both 2.5% benzoyl peroxide gel and 0.1% adapalene gel exhibited comedolytic effects on the spontaneous comedogenic rhino mouse model.