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Some IBD patients on anti-TNFs developed severe skin issues, but ustekinumab helped.

Cytokines are important for immune responses and treating diseases, but they can cause side effects like fever and skin issues.

Some patients on anti-TNF drugs experience a type of hair loss called TAIAPA.

Some medications for inflammation can cause a condition with scalp rashes and hair loss, often linked to Crohn's disease, and may require treatment changes to prevent permanent hair loss.

The new ddPCR method reliably detects unwanted viruses in CAR-T cell products, ensuring their safety for patients.

New Australian advertising rules improved stem cell marketing practices but further regulation is needed for consumer safety.

Patients in Australia underwent costly, unproven stem cell treatments due to weak regulations and aggressive marketing.

Hair loss is common in IBD patients, and some medications may lower the risk.

Researchers identified genes and proteins that may influence wool thickness in sheep.

Elderly patients with CCCA were all African American with low vitamin D, but no iron or zinc deficiencies, and no hormonal imbalances compared to younger patients.

Different cells affect hair follicle blood vessels, endothelial cells react differently to inflammation and oxidized fats, and prasugrel better protects heart vessels during a procedure than clopidogrel.

Prasugrel is better than clopidogrel at preventing heart damage and improving blood flow in small heart vessels during heart artery procedures.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Skin fat plays a key role in immune defense and healing beyond just storing energy.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Lymphatic vessels are essential for hair follicle growth and skin regeneration.

Type I interferons play a key role in the development of various skin diseases.