25 citations
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March 2021 in “Australasian Journal of Dermatology” This case study reports a 70-year-old man with treatment-resistant pityriasis rubra pilaris achieving complete clinical remission with ustekinumab, adding to evidence supporting biologic therapy when TNF inhibitors are unsuitable.
20 citations
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March 2017 in “Journal of cutaneous pathology” This study describes tumor necrosis factor inhibitor-associated psoriatic alopecia, highlighting the distinctive histologic feature of sebaceous lobule atrophy, which is potentially reversible and helps differentiate it from idiopathic psoriatic alopecia.
February 2024 in “PloS one” This review concluded that oral tofacitinib and adalimumab are promising treatments for cicatricial alopecia, showing effectiveness in improving signs and symptoms but requiring regular monitoring for adverse effects. The authors emphasize the need for further extensive studies to solidify these findings.
June 2020 in “Annals of the Rheumatic Diseases” This study surveyed patients with idiopathic inflammatory myopathy and found that glucocorticoid treatment commonly leads to adverse effects, particularly sleep disturbance, mood swings, and weight gain, with more severe effects reported by female patients.
January 2014 in “IOSR journal of pharmacy” This case report identifies alopecia universalis as a probable adverse drug reaction to adalimumab in a patient with psoriasis and psoriatic arthritis.
70 citations
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October 2020 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” This review discusses the JAK-STAT pathway and the use of FDA-approved JAK inhibitors for autoimmune and inflammatory diseases but reports no new research findings.
2 citations
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March 2023 in “Frontiers in medicine” This case report presents the first successful treatment of perifolliculitis capitis abscedens et suffodiens using a regimen of adalimumab and baricitinib, resulting in almost complete healing after nine months.
1 citations
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January 2021 in “Arthritis Research & Therapy” The study reported a 7.80% prevalence of scarring alopecia in Chinese SLE patients and identified several risk factors, including mucocutaneous lesions and high disease activity, while renal and cardio-respiratory involvements were negatively associated with it.
October 2025 in “Dermatology Practical & Conceptual” This review discusses different types of alopecia associated with psoriasis and highlights that hair loss in psoriasis is typically non-scarring and reversible, while also noting the increased risk of alopecia areata in these patients.
January 2013 in “Dermatology” The ILDS Newsletter reported on efforts to support albinism patients in Tanzania and dermatological conferences.
Personalized care and evidence-based treatments are crucial for managing skin and hair conditions.
25 citations
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August 2010 in “Journal of Biological Chemistry” This study found that NFI-C plays a crucial role in the transition from the telogen to anagen phase of the hair follicle cycle, affecting hair growth initiation in mice.
9 citations
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January 2017 in “Dermatology Online Journal” This study describes a distinctive hair loss pattern with features of psoriasis and alopecia areata linked to TNF-α inhibitors, noting various management options despite the lack of consensus guidelines.
11 citations
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August 2019 in “Journal of Molecular Histology” This study found that upregulation of NFIC may enhance proliferation and osteogenic/cementogenic differentiation in rat dental follicle cells.
This research found that nod factor can induce root hair reorientation and gene expression in Medicago truncatula with as little as a single molecule, implicating heterotrimeric G-protein signaling in this process.
1 citations
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January 2021 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that loss of the folliculin protein delays transferrin receptor recycling, leading to iron deficiency and suggesting a role in the mechanisms of Birt-Hogg-Dubé syndrome.
28 citations
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July 2007 in “Development” In this study, inactivating the TAF4 subunit of transcription factor TFIID in mouse epidermis disrupted gene expression linked to skin and hair function, and increased tumor risk.
September 2023 in “Research Square (Research Square)” This study found that TNC + fibroblasts are crucial in neuro-immune interactions in various skin diseases, particularly inflammation and tumors, by engaging extensively with immune cells and overexpressing inflammatory genes, suggesting their significant role in skin abnormalities.
2 citations
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January 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that low temperatures and nitrogen deficiency trigger root hair elongation through a molecular mechanism involving the receptor kinase FERONIA and the TOR Complex 1.
20 citations
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March 2014 in “Molecular Endocrinology” This study suggests that NFIB and STAT5 work together to control cell-specific genetic programs in mammalian tissues, particularly in mammary and hair follicle stem cells.
44 citations
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January 2023 in “New Phytologist” This study found that low temperature triggers root hair elongation in Arabidopsis thaliana through a FERONIA-ROP2-TORC signaling pathway, also activated by nitrogen deficiency.
August 2025 in “BMC Pharmacology and Toxicology” The LTF gene may help predict and manage nonspecific orbital inflammation.
475 citations
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October 2006 in “Proceedings of the National Academy of Sciences” This study suggests that folliculin, mutated in Birt–Hogg–Dubé syndrome, and its partner FNIP1 may play a role in energy and nutrient sensing through the AMPK and mTOR pathways.
January 2013 in “edoc (University of Basel)” This study found that TRF1 plays a crucial role in maintaining pluripotency and stem cell compartments, but it is not a suitable in vivo telomere length marker.
January 2003 in “Hepatology” 1 citations
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May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers identified a temperature-sensitive mutation in the FERONIA gene of plants that prevents root hair formation at elevated temperatures, highlighting its role in maintaining root hair growth and response to plant hormones.
September 2025 in “Digital Commons - RU (Rockefeller University)” This study found that when NFIB was removed in adult mouse hair follicle stem cells, it did not affect their maintenance but unexpectedly led to increased proliferation and differentiation of nearby melanocyte stem cells.
March 2014 in “Journal of The American Academy of Dermatology” TNF-a may not be as involved in certain types of hair loss as previously thought.
September 2023 in “Journal of the American Academy of Dermatology” Certain factors like being female, having high cholesterol, using Medicaid, and previous non-biologic treatments increase the risk of multiple biologic failures in psoriasis patients.
37 citations
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December 2020 in “PLANT PHYSIOLOGY” In this study, the researchers identified a temperature-sensitive mutant in Arabidopsis thaliana, showing disrupted root hair formation and altered responses to plant hormone treatments at elevated temperatures.