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Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

Pure carbon nanotubes are safe for mice, but impure ones cause immune issues and hair loss.

A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

Skin problems in COVID-19 patients are rare and may be due to the body's complex immune response or blood clotting issues.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.

New treatments for male hypogonadism are effective and should be personalized.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.