research Cutaneous Involvement in Systemic Lupus Erythematosus: A Review for the Rheumatologist
Skin problems are common in lupus patients and should be treated early to prevent worsening.
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research A Review of the Most Common Dermatologic Conditions and Their Debilitating Psychosocial Impacts
Common skin conditions can greatly affect a person's mental health and social life.
research Oral Lichen Planus: A Chronic Systemic Disease with Immune-Mediated Pathogenesis
Oral lichen planus is a chronic disease causing mouth discomfort and sometimes needs immunosuppressive treatment.
research Hidradenitis Suppurativa: A Comparison of Guidelines
There is no gold standard treatment for hidradenitis suppurativa due to insufficient evidence.
research Human Regulatory T Cells: Role in Autoimmune Skin Diseases and Post-Transplant Nonmelanoma Skin Cancers
Understanding how Regulatory T Cells work could help create treatments for certain skin diseases and cancers.
research Macrophages Induce AKT/β-Catenin-Dependent Lgr5+ Stem Cell Activation and Hair Follicle Regeneration Through TNF
Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.
research TCL1 Transgenic Mouse Model as a Tool for the Study of Therapeutic Targets and Microenvironment in Human B-Cell Chronic Lymphocytic Leukemia
The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.
research Low-Molecular-Weight Synthetic Antioxidants: Classification, Pharmacological Profile, Effectiveness, and Trends
Synthetic antioxidants are effective, cheap, and stable, with some like zinc and cholecalciferol reducing child and cancer deaths, but the safety of additives like BHA, BHT, TBHQ, and PEG needs more research.
research Rheumatoid Arthritis and Gouty Arthritis in an Adult Patient with Down's Syndrome
A 44-year-old woman with Down's syndrome was diagnosed with both rheumatoid and gouty arthritis and treated with multiple medications.
research Mechanisms Regulating Skin Immunity and Inflammation
The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
research Severe Cutaneous Adverse Reactions to Drugs
Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.
research Green Tea: Health Benefits
Green tea may help with health issues like cancer, heart disease, and weight loss due to its high catechin content.
research Safety of Common Medications for Treating Dermatology Disorders in Pregnant Women
Some skin medications are safe for pregnant women, but others pose risks or should not be used.
research Darier Sign: A Historical Note
Dermatologists diagnose and manage melanoma more effectively than general practitioners.
research Going Below and Beyond the Surface: Microneedle Structure, Materials, Drugs, Fabrication, and Applications for Wound Healing and Tissue Regeneration
Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
research Tumor Necrosis Factor-Alpha Inhibitor Associated Psoriasiform Alopecia (Drug-Induced Psoriasiform Alopecia)
Some patients on anti-TNF drugs experience a type of hair loss called TAIAPA.
research Novel Therapies for Alopecia Areata: The Era of Rational Drug Development
New targeted therapies for hair loss from alopecia areata show promise, with personalized treatment expected in the future.
research Precision Dermatology: A Review of Molecular Biomarkers and Personalized Therapies
Personalized medicine in dermatology uses molecular biomarkers to improve diagnosis and treatment but needs further advancements for practical use.
research Treatment of Cultured Sebocytes with an EGFR Inhibitor Does Not Lead to Significant Upregulation of Inflammatory Biomarkers
Blocking EGFR in skin cells doesn't majorly increase inflammation markers.
research Proteasome Inhibitors: An Expanding Army Attacking a Unique Target
Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.
research TNF Superfamily in Skin Appendage Development
TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.
research Janus Kinase Inhibitors for the Treatment of Severe Alopecia Areata: An Open-Label Comparative Study
Both ruxolitinib and tofacitinib are effective and safe for treating severe alopecia areata, but relapses are common.
research Topical Janus Kinase Inhibitors: A Review of Applications in Dermatology
Topical JAK inhibitors may help treat some skin conditions but need more research.
research Janus Kinase (JAK) Inhibitors for the Treatment of Skin and Hair Disorders: A Review of Literature
JAK inhibitors show promise for treating skin and hair disorders but need more research on long-term safety and effectiveness.
research EGFR Inhibitors and Cutaneous Complications: A Practical Approach to Management
The document provides advice on how to recognize and treat skin-related side effects of cancer drugs known as EGFR inhibitors.
research Steroid Sulfatase Inhibitors: Therapeutic Applications and Development
Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.
research Recalcitrant Alopecia Areata Responsive to Leflunomide and Anthralin—Potentially Undiscovered JAK/STAT Inhibitors?
Leflunomide and anthralin may effectively treat severe alopecia areata.
research The Cutaneous Side Effects of Selective BRAF Inhibitors and Anti-CTLA4 Agents: The Growing Role of the Dermatologist in the Management of Patients with Metastatic Melanoma
Dermatologists are crucial for managing skin side effects in metastatic melanoma patients using vemurafenib and ipilimumab.
research The Use of Phosphodiesterase Inhibitors for the Treatment of Alopecia
Caffeine shows promise for treating some types of hair loss, but more research is needed.
research Screening for Latent Infectious Disease in Patients with Alopecia Areata Before Initiating JAK Inhibitors Therapy: A Single-Center Real-World Retrospective Study
Comprehensive screening for infections is crucial before starting JAK inhibitors in alopecia areata patients.