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This study found that adding platelet-rich plasma to microneedling improved outcomes for atrophic acne scars more than microneedling alone, according to both quantitative and qualitative assessments.

This article reviews the role of skin surface lipid in mediating environmental stressors and discusses potential therapeutic interventions, reporting no new experimental findings.

This research article focuses on nonsteroidal inhibitors of human type I steroid 5-alpha-reductase but reports no new results.

This review discusses the current research and development of mannosylerythritol lipids, particularly focusing on their potential commercial applications in cosmetics; it reports no new results.

This study found that the progestins norgestimate and dienogest may help treat clinical hyperandrogeny in women by inhibiting skin 5 alpha-reductase activity with minimal androgenic potential.

This review discusses the use of Dermal Papilla cells as in vitro models for studying hair growth modulators, emphasizing their role in aiding the development of new hair treatments, but reports no new clinical results.

This review discusses the properties and therapeutic potentials of beta-sitosterol, highlighting a need for more detailed studies on its mechanisms and long-term effects in humans; it reports no new results.

This study found that Sophora flavescens extract may promote hair growth in mice by inducing earlier hair cycle changes and regulating growth factors in dermal papilla cells.

This study discovered nine human type I hair keratin genes, including a transcribed pseudogene, in a 190 kbp genomic region, revealing three gene subclusters based on sequence homologies.

This study found that topical formulations including extracts from Cuscuta reflexa, Citrullus colocynthis, and Eclipta alba significantly accelerated hair growth initiation and completion in rats, indicating potential benefits for treating alopecia.

This study found that Mentha pulegium essential oil had a stronger protoscolicidal effect against Echinococcus granulosus in vitro than Mentha piperita, showing dose- and time-dependent effects.

The researchers reported that the petroleum ether extract of Cuscuta reflexa may promote hair growth in testosterone-induced alopecia in mice by inhibiting the enzyme 5α-reductase.

This study found that the EtOAc extract of Tridax procumbens aerial parts significantly inhibited rat paw edema and COX enzyme activity, suggesting its potential anti-inflammatory properties.

The researchers reported that during early embryogenesis and larval development in Silurana tropicalis, inhibiting steroidogenic enzymes cyp19 and srd5beta affects genes related to thyroid and reproductive systems.

This review discusses current therapeutic targets and treatments for androgenic alopecia but reports no clinical results; the authors highlight the challenge of developing multi-target drugs for effective treatment.

This study identified novel compounds from Bombax ceiba stem bark, including shamimicin, with potent hypotensive effects, and reported that a specific fraction had adverse effects on heart, liver, and kidneys in mice.

This review examines the physiological role of androgen conjugates in cutaneous androgen metabolism and questions their association with hirsutism, without presenting new clinical findings.

This study screened synthesized pyridinecarboxamides for antitumor properties and found that many, particularly 5c and 7a, showed moderate in vitro activity against various human tumor cell lines.

In this cell study, Eclipta alba extract inhibited cancer cell proliferation and induced apoptosis, showing potential antiproliferative and anti-metastasis effects on liver and related cancer cell lines.

This study found that topical Rosmarinus officinalis leaf extract improved hair regrowth in mice and inhibited androgen-associated mechanisms involved in hair loss.

This study found that C. obtusa oils promoted hair growth in shaved mice and increased the expression of a hair growth regulator, VEGF, in a cell line.

In this study, researchers isolated and identified diverse endophytes from plants in Asia, finding that these microorganisms have significant potential for producing useful metabolites, including enzymes and antibiotics.

This study found that finasteride competitively inhibits the enzyme AKR1D1 with low micromolar affinity but does not act as a mechanism-based inactivator.

This study showed that Thujae occidentalis semen extract inhibited 5alpha-reductase type 2 in laboratory tests and reduced androgen-related hair loss in animal models, suggesting potential use for male pattern baldness.

This review compiles current information about Eclipta prostrata, traditional uses, and its promising pharmacological properties, like hepatoprotective and anti-inflammatory effects, but emphasizes that more research is needed to fully understand its mechanisms and ensure safety for clinical application.

In this study, ketoconazole treatment improved acne in all women and reduced hirsutism in some, but it caused several side effects and requires careful monitoring.

This study found that overexpression of AKR1C3 in prostate cancer cells redirected androgen metabolism towards testosterone production, which facilitated cell proliferation, potentially reducing the effectiveness of finasteride treatment.

This study found that SRD5a-3 is a highly efficient enzyme for converting hormones into androgens, with dutasteride being a much more potent inhibitor of SRD5a-3 than SRD5a-2.

This study found that novel androgen antagonists incorporating a carborane moiety showed anti-androgenic activity comparable to flutamide in a laboratory setting.

This study reported that certain newly synthesized steroidal derivatives showed stronger inhibitory activity against the 5α-reductase enzyme than finasteride in hamsters, suggesting their potential as enzyme inhibitors.