December 2023 in “Medicine” This study observed that platelet-rich gel for scalp defect reconstruction was more cost-effective and less painful but resulted in poorer hair growth compared to the external tissue expansion technique.
November 2014 in “Hair transplant forum international” This discussion presents insights by Dr. Jonathan Ballon but does not report new clinical findings.
January 2024 in “Medicina” This study assessed outcomes and complications of upper-face feminization surgery among 20 transgender patients, highlighting that insufficient browbone reduction was a common issue in prior surgeries, and emphasizing meticulous planning to prevent revisions and dissatisfaction.
80 citations
,
January 2020 in “Journal of Nanobiotechnology” This review highlights that incorporating nanomaterials into scaffolds can significantly enhance angiogenesis in tissue regeneration by simulating extracellular matrix structures and effectively delivering angiogenesis-related factors, offering promising designs for vascularization and therapeutic applications.
38 citations
,
May 1982 in “PubMed” This report describes almost complete resolution of calcinosis and healing of associated ulcers in an 83-year-old woman with localized scleroderma after repeated intralesional steroid injections.
294 citations
,
January 2016 in “Stem Cells International” This review discusses the characteristics, biomaterials, and tissue engineering methods for adipose-derived stem cells in a 3D environment, highlighting their potential in regenerative medicine without presenting new clinical results.
3 citations
,
February 2023 in “International Journal of Molecular Sciences” This review discusses the composition, preparation, and applications of autologous platelet and extracellular vesicle-rich plasma, highlighting its potential benefits and the need for further research, but it reports no new clinical findings.
133 citations
,
July 2020 in “Cells” This review discusses the modern approach of skin tissue engineering for chronic wound treatment, focusing on bioengineered artificial skin substitutes and assessing innovations in biomaterials and cell use; it reports no new clinical results.
110 citations
,
April 2020 in “Advances in Wound Care” This review discusses recent advancements in nanotechnology-based treatments for chronic wound healing in diabetic models, noting that despite promising results, these innovations have yet to translate into widely available commercial products.
92 citations
,
February 2023 in “Antibiotics” This review discusses advances in nanomaterial-based wound dressings for infection control, highlighting their ability to detect and treat bacterial infections effectively, but reports no new clinical results.
72 citations
,
November 2020 in “Frontiers in Surgery” This review found that the clinical results of L-PRF as a grafting material in maxillary sinus augmentation were mixed, with some studies reporting positive effects and others finding no significant impact.
61 citations
,
April 2023 in “Bioactive Materials” This review article highlights recent advances in microneedle technology for wound healing and tissue regeneration, discussing various cargo types, structural designs, and fabrication methods, and suggesting guidelines for designing microneedle systems tailored to specific applications.
50 citations
,
February 2022 in “Nanomaterials” This review discusses the mechanisms involved in wound healing and explores the potential of nanomaterials as a promising approach to managing chronic wounds, but reports no new clinical findings.
47 citations
,
August 2024 in “Science Advances” This study introduces a new biomimetic double wound mask designed to promote scarless healing by coordinating multiple biological pathways and providing enhanced protection and nourishment to wounds.
42 citations
,
June 2021 in “Pharmaceutics” This review summarizes the use of 3D printing technologies for creating microneedles and evaluates their associated benefits, challenges, and regulatory considerations, but does not present new experimental results.
40 citations
,
July 2024 in “Bioengineering” This review found significant progress in 3D bioprinting for surgery, noting advances in creating complex tissue constructs, while highlighting ongoing challenges like vascularization and integration with host tissue, emphasizing the need for further research and regulatory development.
37 citations
,
February 2024 in “Military Medical Research” In this review, biomaterial-based mechanical strategies were highlighted for their potential to enhance skin regeneration and promote scarless repair, though a comprehensive understanding of their underlying mechanisms is still needed for broader application.
32 citations
,
June 2024 in “Pharmaceutics” This review explores the use of topical and transdermal delivery for drugs and cosmetics, highlighting the benefits of avoiding side effects and rapid metabolism, with a focus on nanoparticulate formulations and techniques for studying skin penetration.
30 citations
,
November 2024 in “ACS Materials Au” This article provides an overview of microneedle technology for transcutaneous drug delivery, discussing microneedle designs, materials, and activation methods that enhance drug stability and regulated release, and outlines considerations for their successful clinical implementation, such as biocompatibility and production cost.
30 citations
,
February 2022 in “Pharmaceutics” This review explores recent advancements in skin tissue engineering using 3D bioprinting, discussing current methods, bioink formulations, and outlining both achievements and limitations without presenting new clinical results.
26 citations
,
November 2022 in “European journal of medical research” This review discusses the potential of nanoparticles to modify angiogenesis processes for therapeutic applications and reports no new clinical results, highlighting challenges and future prospects in treating angiogenesis-related diseases.
24 citations
,
August 2023 in “International Journal of Molecular Sciences” This review discusses the use of platelet-rich fibrin (PRF) in musculoskeletal, oral, and maxillofacial surgeries and dermatology, but reports no new clinical results; further trials are needed.
21 citations
,
February 2023 in “Pharmaceuticals” This study reports that extracts from pomegranate leaves contain bioactive compounds with antioxidant, antimicrobial, and skin-beneficial properties, suggesting their potential use in nutraceutical and cosmeceutical applications.
19 citations
,
January 2019 in “Molecular Medicine Reports” This study found that for optimal ADSC viability during short-term storage, using 10% human serum at 4°C and utilizing the cells within 2 hours is most effective.
17 citations
,
October 2023 in “Polymers” This review highlights advancements in electrospun nanofibers, focusing on their potential applications in biomedical technologies, chemical and biological sensing, and energy harvesting within IoT devices.
17 citations
,
October 2023 in “Science Progress” This review discusses the biological properties and potential applications of PCL and barium titanate composites in biomedical fields and reports no new experimental findings; the authors highlight the need for further research.
13 citations
,
February 2023 in “Pharmaceutics” This review outlines strategies for regulating macrophage response using bioactive materials to enhance wound healing, focusing on extracellular matrix-based scaffolds and nanofibrous composites, but reports no new clinical results.
11 citations
,
August 2025 in “Journal of Periodontal Research” This review highlights that autologous platelet concentrates, particularly platelet-rich fibrin, have shown potential to enhance healing and outcomes in both dental and medical applications, including injury recovery and aesthetics.
10 citations
,
May 2025 in “Cell Biomaterials” This perspective highlights how advancements in single-cell sequencing and digital pathology can help understand the complex mechanisms of immune responses, fibrosis, and tissue remodeling related to medical implants, aiming to address the challenges of implant-related tissue reactions reported in this study.
8 citations
,
September 2024 in “International Journal of Molecular Sciences” This review discusses how polymers can be customized to develop biomaterials that mimic the extracellular matrix, exploring their potential in biomedical and biotechnological applications by triggering cell functions similar to natural physiological systems.