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The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Hair follicles greatly increase caffeine absorption through the skin shortly after it's applied.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Growth factors are crucial for hair development and could help treat hair diseases.

Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Mutant mice help researchers understand hair growth and related genetic factors.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.