33 citations,
January 2021 in “Aesthetic Surgery Journal” Low-Level Light Therapy (LLLT) is a safe and effective method for skin rejuvenation, acne treatment, wound healing, body contouring, and hair growth, but more well-designed trials are needed for confirmation.
29 citations,
July 2009 in “BJU international” Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.
29 citations,
April 1995 in “Endocrinology” Finasteride doesn't affect bone density in male rats.
28 citations,
December 2019 in “Skin appendage disorders” Some medications might reverse gray hair, especially those that reduce inflammation or stimulate pigment production, and vitamin B might help.
28 citations,
April 1996 in “Cell biology international” Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.
27 citations,
May 2006 in “Biochemical and Biophysical Research Communications” Wnt-10b is important for starting hair growth and developing hair follicles.
25 citations,
November 2014 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
25 citations,
February 2009 in “The Journal of Urology” Short-term finasteride treatment may lower some cell death factors in prostate cancer cells.
23 citations,
January 2021 in “Scientific Reports” Adding human blood vessel cells to hair follicle germs may improve hair growth and quality.
23 citations,
September 2015 in “International Journal of Molecular Medicine” Activating ER-β, not ER-α, improves skin cell growth and wound healing.
20 citations,
January 2021 in “Plants” High energy boosts root hair growth in plants, while low energy stops it.
19 citations,
January 2018 in “BioMed Research International” miR-195-5p reduces hair growth ability in cells by blocking a specific growth signal.
18 citations,
March 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
18 citations,
November 2018 in “Facial Plastic Surgery Clinics of North America” Lasers, microneedling, and PRP improve skin rejuvenation and repair, with PRP enhancing the effects when combined with other treatments.
17 citations,
August 2011 in “Current Medicinal Chemistry” New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.
17 citations,
June 1996 in “The Journal of Steroid Biochemistry and Molecular Biology” FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.
13 citations,
December 2019 in “Nutrients” An apple-based supplement was found to stimulate hair protein production, which may help with hair growth.
13 citations,
November 2019 in “Scientific reports” Certain drugs change freshwater snail shells to a "banana" shape.
13 citations,
September 2019 in “Scientific Reports” High levels of the protein Flightless I worsen ulcerative colitis symptoms in mice.
13 citations,
January 1999 in “Postgraduate Medicine” New drugs for rheumatoid arthritis show improvement but have side effects and are not a cure.
11 citations,
March 2019 in “EMBO molecular medicine” A defective protein in progeria causes cell death and atherosclerosis, but a treatment targeting cell stress may reduce these effects.
11 citations,
May 1996 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.
10 citations,
November 2010 in “Pigment Cell & Melanoma Research” Only skin melanocytes, not other types, can color hair in mice.
10 citations,
January 2009 in “Elsevier eBooks” Hair growth is influenced by hormones and goes through different phases; androgens can both promote and inhibit hair growth depending on the body area.
9 citations,
August 2021 in “Biological Chemistry” ECM-inspired wound dressings can help heal chronic wounds by controlling macrophage activity.
8 citations,
May 2021 in “Bioengineering & translational medicine” Hair growth environment recreated with challenges; stem cells make successful skin organoids.
8 citations,
January 2020 in “Skin Pharmacology and Physiology” Caffeine improves hair growth, thickness, and reduces shedding.
7 citations,
May 2020 in “Trends in molecular medicine” The document concludes that the immune-inhibitory environment of the hair follicle may prevent melanoma development.
7 citations,
January 1994 in “Annual Reports in Medicinal Chemistry” Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.
6 citations,
August 1996 in “The Journal of Clinical Endocrinology and Metabolism” MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.