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High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

Animal models have helped understand hair loss from alopecia areata and find new treatments.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Multiple treatments work best for hair loss.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.

Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.

Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.

Suppressing certain hormones might help prevent prostate cancer.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

New treatments for skin conditions related to the sebaceous gland are being developed based on current research.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

New technologies help us better understand how skin microbes affect skin diseases.

Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

Chicken feather gene mutation helps understand human hair disorders.

Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.

Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.