44 citations
,
September 2019 in “The EMBO Journal” This study found that lymphatic vessels in mice are important for hair follicle development and organization, as their depletion blocks hair growth.
34 citations
,
July 1999 in “Journal of The European Academy of Dermatology and Venereology” Iron deficiency is not a significant cause of hair loss in women.
128 citations
,
September 2011 in “British Journal of Dermatology” Obesity is linked to various skin problems and may increase the risk of skin cancer.
4 citations
,
May 2024 in “Biomolecules” This study examined connections between bioelements like Zn, Cu, and Mn in serum and bone tissue and hormone concentrations in men with and without erectile dysfunction, highlighting potential relationships that may help explain ED's etiology.
19 citations
,
February 2018 in “Nutrients” This review discusses the relationship between zinc deficiency and skin disorders, emphasizing zinc transporters' roles, but it reports no new clinical results; the authors highlight potential benefits of regulating zinc levels via transporters.
1 citations
,
February 2022 in “Experimental Dermatology” This study found that the secretory profiles of adipose-derived stem cells vary between balding and non-balding scalp areas in androgenetic alopecia patients, suggesting involvement of angiogenic and inflammatory processes in the condition's development.
22 citations
,
October 2012 in “Journal of Investigative Dermatology” This study found that C57BL/6 mice with a diet containing specific levels of vitamin A showed alterations in retinoid metabolism and increased frequency of cicatricial alopecias, suggesting dietary factors may play a role in this condition.
46 citations
,
May 2012 in “Molecular and Cellular Endocrinology” In this study, higher expression levels of aromatase and steroidogenic acute regulatory protein were correlated with increased estrogen synthesis and fewer hair follicles in human skin, suggesting a link to elastic fiber formation and hair growth.
4 citations
,
June 2023 in “Frontiers in Aging” This scoping review evaluates the connection between hypoxia and declining sex hormonal signaling in middle-aged individuals, proposing a "middle-aging hypovascularity hypoxia hypothesis" as a potential mechanism influencing age-related diseases, with implications for developing strategies to maintain healthspan.
2 citations
,
March 2022 in “Journal of Personalized Medicine” Personalized medicine is important for treating skin disorders, with new treatments and connections to hormones and genetics being explored.
11 citations
,
January 2000 in “Journal of Cutaneous Pathology” This paper reviews the role of the telomere-telomerase system in cellular ageing and cancer, discussing potential therapies but reporting no new experimental results.
October 2024 in “Benha Journal of Applied Sciences” This study examined the association between aging and androgenetic alopecia, suggesting a strong interplay among chronic inflammation, metabolic dysregulation, and increased oxidative stress as contributing factors.
January 2008 in “Информационно-управляющие системы” This review outlines the physiological roles of zinc transporters and their involvement in human diseases, emphasizing their molecular, biochemical, and genetic mechanisms without presenting new research findings.
1 citations
,
January 2022 in “Wiadomości Lekarskie” In this study, GERD symptoms were found to be significantly related to acid exposure time and the intensity of excessive daytime sleepiness, which depends on circulating ghrelin levels.
January 2024 in “International Journal of Dermatology Venereology and Leprosy Sciences” This study reports that an intervention decreased glucose and insulin levels, indicating improved insulin resistance, which is linked to a skin condition called acne vulgaris and other disorders associated with insulin resistance.
7 citations
,
February 2018 in “Journal of Investigative Dermatology” This study investigates the role of peroxisome proliferator-activated receptor gamma in hair follicle morphogenesis using a novel mouse model but reports no new results, highlighting the need for further research on its function during the hair cycle.
2 citations
,
November 2025 in “Journal of Ovarian Research” This study found that in a mouse model of PCOS, high androgen levels caused pyroptosis in ovarian granulosa cells and increased ER stress in oocytes, reducing oocyte maturation rates, while treatment with CPA and DMF improved these rates.
2 citations
,
April 2019 in “Experimental Dermatology” The article concludes that studying how skin forms is key to understanding skin diseases and improving regenerative medicine.
3 citations
,
December 2011 in “Pediatric Dermatology” In this case report, estrogen substitution therapy slightly increased hair volume in a 22-year-old patient with genetic predisposition to hair loss and alopecia caused by past treatment for leukemia, but hair loss returned after stopping the therapy.
32 citations
,
July 2011 in “Facial Plastic Surgery” This review discusses recent surgical and medical advancements in hair restoration techniques but reports no new clinical results.
February 1956 in “Bulletin of Experimental Biology and Medicine” Glycogen levels in mouse skin drop after injury but increase during healing, returning to normal within a month.
28 citations
,
August 2015 in “Journal of Drug Targeting” This study found that a novel proniosomal gel formulation of CoQ10 improved antioxidant levels and provided better skin protection against UV radiation compared to a conventional CoQ10 gel in animal models.
27 citations
,
September 2012 in “Dermatologic Clinics” This review outlines a systematic method for diagnosing hair loss and presents no new findings; the authors emphasize the importance of biopsy in cicatricial alopecia cases.
94 citations
,
August 1975 in “Journal of Cutaneous Pathology” In this study, the researchers observed that male pattern alopecia is characterized by miniature follicles, enlarged sebaceous glands, and an increased number of mast cells, without significant abnormalities in enzyme activity.
8 citations
,
July 2019 in “Endocrine connections” This study found that post-finasteride syndrome patients showed a tissue-specific methylation pattern of the SRD5A2 promoter in cerebrospinal fluid, potentially affecting neuroactive steroid levels and related behavioral symptoms.
January 2026 in “Metabolites” This study analyzed gene expression profiles from multiple tissues to explore the molecular connections between obesity and immune-related processes, identifying potential links and pathways that may require further experimental validation to understand their roles in obesity fully.
20 citations
,
August 2022 in “Frontiers in Immunology” This review discusses the role of fibroblasts in treating diabetic complications and wound healing, highlighting their potential as immunomodulatory factors but provides no new clinical results.
1 citations
,
July 2023 in “Cureus” This article examines advancements in understanding and managing androgenic alopecia (male pattern baldness), discussing genetic and psychological factors, diagnostic methods, classifications, and various treatment options, including traditional and emerging therapies, to aid healthcare professionals in making informed treatment decisions.
May 2020 in “Authorea (Authorea)” This review discusses the diverse functions and therapeutic potential of ectopic olfactory receptors throughout the body, emphasizing their roles in various cellular processes and potential in cancer detection and therapy, but reports no new clinical results.
January 2026 in “Dermatologic Therapy” This study found that elevated tissue RBP4 levels correlate with disease severity in alopecia areata and decrease after effective baricitinib treatment, while the rs3758539 polymorphism is linked to disease susceptibility but not to treatment response.