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    Research 301–330 of 1000+

    1. New aspects of vitamin D metabolism and action — addressing the skin as source and target Nature Reviews Endocrinology · 2020 · 378 citations
    2. Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity Nature Genetics · 2004 · 372 citations
    3. Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases Cell · 2020 · 227 citations
    4. The expanding significance of keratin intermediate filaments in normal and diseased epithelia Current opinion in cell biology · 2012 · 186 citations
    5. Patched1 Functions as a Gatekeeper by Promoting Cell Cycle Progression Cancer Research · 2006 · 176 citations
    6. Microencapsulating Alginate-Based Polymers for Probiotics Delivery Systems and Their Application Pharmaceuticals · 2022 · 143 citations
    7. Regulation of Involucrin Gene Expression Journal of Investigative Dermatology · 2004 · 138 citations
    8. Evidence for Novel Functions of the Keratin Tail Emerging from a Mutation Causing Ichthyosis Hystrix Journal of Investigative Dermatology · 2001 · 130 citations
    9. Nanoparticles for Topical Application in the Treatment of Skin Dysfunctions—An Overview of Dermo-Cosmetic and Dermatological Products International Journal of Molecular Sciences · 2022 · 122 citations
    10. Pemphigus Vulgaris IgG and Methylprednisolone Exhibit Reciprocal Effects on Keratinocytes Journal of Biological Chemistry · 2004 · 99 citations
    11. A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity The Journal of Cell Biology · 2015 · 98 citations
    12. A Novel Epithelial Keratin, hK6irs1, is Expressed Differentially in All Layers of the Inner Root Sheath, Including Specialized Huxley Cells (Flügelzellen) of the Human Hair Follicle Journal of Investigative Dermatology · 2002 · 86 citations
    13. KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin Development · 2009 · 82 citations
    14. Structural and Immunocytochemical Characterization of Keratinization in Vertebrate Epidermis and Epidermal Derivatives International review of cytology · 2006 · 82 citations
    15. The Two Functional Keratin 6 Genes of Mouse Are Differentially Regulated and Evolved Independently from Their Human Orthologs Genomics · 1998 · 79 citations
    16. Specific Citrullination Causes Assembly of a Globular S100A3 Homotetramer 2007 · 62 citations
    17. “Sebocytes’ makeup” - Novel mechanisms and concepts in the physiology of the human sebaceous glands 2011 · 58 citations
    18. Deimination and Peptidylarginine Deiminases in Skin Physiology and Diseases International Journal of Molecular Sciences · 2020 · 57 citations
    19. Drug repurposing: A novel strategy to target cancer stem cells and therapeutic resistance Genes & Diseases · 2023 · 56 citations
    20. Structure and Mechanical Properties of Human Trichocyte Keratin Intermediate Filament Protein Biomacromolecules · 2012 · 51 citations
    21. Multifaceted role of keratins in epithelial cell differentiation and transformation Journal of Biosciences · 2019 · 50 citations
    22. Androgen Regulation of the Human Hair Follicle: The Type I Hair Keratin hHa7 Is a Direct Target Gene in Trichocytes Journal of Investigative Dermatology · 2004 · 49 citations
    23. Gene variants associated with acne vulgaris presentation and severity: a systematic review and meta-analysis BMC Medical Genomics · 2021 · 47 citations
    24. The nude gene and the skin Experimental Dermatology · 2001 · 41 citations
    25. Expression of truncated latent TGF-β-binding protein modulates TGF-β signaling Journal of Cell Science · 2005 · 40 citations
    26. Disturbed Epidermal Structure in Mice with Temporally Controlled Fatp4 Deficiency 2005 · 39 citations
    27. Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models Archives of Toxicology · 2018 · 38 citations
    28. Oxidative Stress and Skin Diseases: The Role of Lipid Peroxidation Antioxidants · 2025 · 36 citations
    29. Hair Follicular Expression and Function of Group X Secreted Phospholipase A2 in Mouse Skin Journal of Biological Chemistry · 2011 · 35 citations
    30. Epidermal mammalian target of rapamycin complex 2 controls lipid synthesis and filaggrin processing in epidermal barrier formation Journal of Allergy and Clinical Immunology · 2019 · 34 citations