research Alopecia Areata: Pathogenesis, Genetic Factors, and Treatments Using Mouse Models
The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.
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research Hair Loss and Hirsutism in the Elderly
Many elderly women experience unwanted facial hair and various hair loss conditions, with treatments available for each condition.
research Effects of Finasteride, a 5 Alpha-Reductase Inhibitor, on Circulating Androgens and Gonadotropin Secretion in Hirsute Women
Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.
research Androgens Modulate Keratinocyte Differentiation Indirectly Through Enhancing Growth Factor Production From Dermal Fibroblasts
Male hormones indirectly affect skin cell development by increasing growth factor levels from skin fibroblasts.
research Clinical Case Seminar: Postmenopausal Androgen Excess - Challenges in Diagnostic Work-Up and Management of Ovarian Thecosis
The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.
research The Endocrinology of Baldness
Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.
research Systemic Causes of Hair Loss
The article concludes that correctly diagnosing systemic causes of hair loss requires a detailed clinical evaluation and a systematic diagnostic approach.
research The Utility of Metformin Therapy in Reproductive-Aged Women with Polycystic Ovary Syndrome
Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.
research How to Diagnose and Treat Women with Excessive Hair
Treating excessive hair in women requires a holistic approach, including medical, aesthetic, and emotional support.
research The 5alpha-Reductase Type 1, But Not Type 2, Gene Is Expressed in Anagen Hairs Plucked from the Vertex Area of the Scalp of Hirsute Women and Normal Individuals
The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.
research Androgenic Disorders of Women: Diagnostic and Therapeutic Decision Making
The document concludes that proper diagnosis and tailored long-term treatment can effectively manage androgenic disorders in women, improving patient care outcomes.
research Safety Aspects of Androgen Treatment with 5α-Dihydrotestosterone
DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.
research Targets to Treat Androgen Excess in Polycystic Ovary Syndrome
The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
research Finasteride Inhibited Brain Dopaminergic System and Open-Field Behaviors in Adolescent Male Rats
Finasteride affects young male rats' brain function and behavior negatively.
research An Ovarian Leydig Cell Tumor Undetected by Ultrasound in a Postmenopausal Woman with Hirsutism and Hyperandrogenism
A postmenopausal woman's hirsutism and high testosterone levels improved after surgery for an ovarian tumor not seen on ultrasound.
research Molecular Basis of Androgen Action on Human Sexual Desire
Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.
research Metabolic Dysfunction in Female Mice with Disruption of 5α-Reductase 1
Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.
research Hirsutism and Virilization
Hirsutism is common body hair growth due to genetics and hormones, and while not a disease, it can be distressing; virilisation includes hirsutism with other male traits and needs medical attention.
research Finasteride-Induced Inhibition of 5α-Reductase Type 2 Could Lead to Kidney Damage: An Experimental Animal Study
Finasteride may cause kidney damage.
research Progestogens in Menopausal Hormone Therapy
Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.
research Finasteride
Finasteride reduces prostate cancer risk but may increase high-grade cancer chances.
research The Diagnosis and Management of Hirsutism
The article explains how to identify and treat excessive hair growth in women, which can be distressing and may signal other health problems.
research Polymeric Micelle Mediated Follicular Delivery of Spironolactone: Targeting the Mineralocorticoid Receptor to Prevent Glucocorticoid-Induced Activation and Delayed Cutaneous Wound Healing
Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.
research Topical L-Thyroxine: The Cinderella Among Hormones Waiting to Dance on the Floor of Dermatological Therapy?
Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.
research Diagnosis and Management of Polycystic Ovary Syndrome (PCOS)
The document concludes that managing PCOS involves treating symptoms, regulating periods, and reducing health risks, with specific medications for fertility and metabolic issues.
research Hirsuties
Hirsutism in women is often due to hormone sensitivity and has significant psychological effects.
research The Post-Finasteride Syndrome: Clinical Manifestation of Drug-Induced Epigenetics Due to Endocrine Disruption
Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.
research Hyperadrenocorticism in Ferrets
Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.
research Pregnancy and the Hair Growth Cycle: Anagen Induction Against Hair Growth Disruption Using Nourkrin with Marilex, a Proteoglycan Replacement Therapy
Nourkrin® with Marilex® may increase hair count by 35.7% in postpartum hair loss.
research 5α-Reductase Inhibitors: Progress and Therapeutic Potential
5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.