December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” AP-2α and AP-2β proteins are essential for healthy adult skin and hair.
September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” FOL-026 peptide can help repair blood vessels and promote growth, offering potential treatment for vascular diseases.
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” KIF18B is important for correctly positioning cell division machinery in skin cells, affecting hair follicle development.
September 2017 in “Journal of Investigative Dermatology” The research concluded that hyaluronic acid affects the formation and growth of hair follicle-like structures in a lab setting.
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
August 2016 in “Journal of Investigative Dermatology” Zinc deficiency disrupts hair growth and cycle, but zinc supplements can fix this.
April 2015 in “Plastic and Reconstructive Surgery” Activating TLR3 helps improve skin and hair follicle regeneration after wounds.
November 2014 in “Journal of Cell Biology” Valentina Greco's research shows that the environment around hair follicle stem cells is more crucial for regeneration than the stem cells themselves.
November 2013 in “Elsevier eBooks” Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.
September 2013 in “Molecular Biology” The document suggests that activating autophagy might help with regeneration by removing old and damaged cells.
721 citations,
October 2011 in “Nature” Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.
277 citations,
July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
232 citations,
October 2015 in “International journal of molecular sciences” Stem cells are crucial for skin repair and new treatments for chronic wounds.
188 citations,
May 2009 in “Plant physiology” Researchers found 19 genes important for root hair growth in a plant called Arabidopsis.
165 citations,
September 2001 in “Genes & development” CDP is crucial for lung and hair follicle cell development.
147 citations,
September 2006 in “Developmental Cell” Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.
145 citations,
November 2018 in “Nature Communications” The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.
86 citations,
May 2008 in “Cytokine & growth factor reviews” TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.
65 citations,
January 2018 in “Nature Reviews Endocrinology” Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.
65 citations,
September 2004 in “The American journal of pathology” Blocking BMP signaling causes hair loss and disrupts hair growth cycles.
59 citations,
March 2020 in “Journal of Biomedical Science” Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.
59 citations,
February 2012 in “Journal of Dermatological Science” Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.
50 citations,
August 1999 in “Experimental dermatology” The control system for hair growth cycles is not well understood and needs more research.
45 citations,
August 2018 in “Stem Cells International” Stem cells, especially from fat tissue and Wharton's jelly, can potentially regenerate hair follicles and treat hair loss, but more research is needed to perfect the treatment.
44 citations,
June 2018 in “Journal of Cellular Physiology” Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.
44 citations,
December 1991 in “Annals of the New York Academy of Sciences” EGF and FGF help hair growth by affecting cell differentiation and fiber growth.
35 citations,
March 2014 in “British Journal of Dermatology” Hair loss in male pattern baldness involves muscle degeneration and increased scalp fat.
33 citations,
September 2012 in “Wound Repair and Regeneration” Applying calreticulin can speed up wound healing in diabetics.
32 citations,
May 2018 in “Cell Cycle” Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.
30 citations,
April 2017 in “Experimental Dermatology” Hair follicle stem cells and skin cells show promise for hair and skin therapies but need more research for clinical use.