169 citations,
February 2018 in “Immunity” Inactive stem cells in hair follicles and muscles can avoid detection by the immune system.
48 citations,
June 1988 in “PubMed” Minoxidil sulfate relaxes muscle by increasing potassium flow, making it a unique muscle relaxer.
33 citations,
January 2018 in “The International Journal of Developmental Biology” Cell aging can be both good and bad for tissue repair.
6 citations,
May 2009 in “Cell transplantation” Green tea component EGCG helps keep rat skin grafts viable longer.
1 citations,
September 2021 in “Advances in skin & wound care” SARS-CoV-2 might infect and multiply in skin tissue, possibly aiding in its transmission.
132 citations,
January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
88 citations,
July 2019 in “International Journal of Molecular Sciences” Using human fat tissue derived stem cells in micrografts can safely and effectively increase hair density in people with hair loss.
21 citations,
October 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” A specific gene change plus an additional mutation in the same gene cause hereditary trichilemmal cysts.
8 citations,
May 2023 in “Gels” Chitosan hydrogels are promising for repairing blood vessels but need improvements in strength and compatibility.
6 citations,
January 2017 in “Advances in Experimental Medicine and Biology” Runx genes are important for stem cell regulation and their roles in aging and disease need more research.
February 2023 in “PubMed” The Wnt/β-catenin signaling pathway is important for skin wound healing and affects inflammation, cell growth, and other healing processes.
April 2017 in “Journal of Investigative Dermatology” Chemotherapy and radiation therapy cause skin and hair damage by altering gene expression and signaling pathways.
318 citations,
January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
185 citations,
August 2005 in “Autoimmunity Reviews” Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.
6 citations,
October 2022 in “Frontiers in Cell and Developmental Biology” Transplanted hair follicle stem cells can heal damaged rat intestines.
March 2022 in “Book Publisher International (a part of SCIENCEDOMAIN International)” Human hair has bipolar electrical charges due to gaps in the hair follicle's electromagnetic fields.
189 citations,
July 2009 in “The Journal of clinical investigation/The journal of clinical investigation” Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.
82 citations,
June 2020 in “Inflammation Research” Skin problems in COVID-19 patients are rare and may be due to the body's complex immune response or blood clotting issues.
57 citations,
June 2021 in “Polymers” Photothermal hydrogels are promising for infection control and tissue repair, and combining them with other treatments could improve results and lower costs.
2 citations,
November 2023 in “Biomolecules” WNT signaling is crucial for skin development and healing.
January 2022 in “SSRN Electronic Journal” Mouse hair follicles age, causing more white hairs due to fewer pigment stem cells.
6 citations,
August 2015 in “Journal of Molecular Histology” Caspase-7 has functions in skin and hair that are not related to cell death.
June 2001 in “Proceedings of SPIE” Low energy laser therapy effectively treats certain skin conditions and improves recovery time without side effects.
90 citations,
January 2003 in “The Journal of Urology” Finasteride may reduce prostate bleeding by lowering blood vessel growth factor levels and blood vessel density in certain prostate areas.
16 citations,
November 2019 in “Dermatologic Surgery” Platelet-rich plasma is most effective for hair loss treatment and shows promise for skin healing and rejuvenation, but more standardized research is needed.
8 citations,
September 2008 in “Medical Hypotheses” The paper suggests that hair loss might be caused by skull growth, not just DHT's effect on hair follicles, and calls for more research.
39 citations,
September 2011 in “Tissue Engineering Part B-reviews” Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.
16 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.
6 citations,
November 2018 in “Histochemistry and Cell Biology” Mongolian gerbils heal wounds differently than mice, with unique protein levels and gene expression that affect skin repair.
135 citations,
December 2006 in “PLoS Medicine” Hyaluronate fragments can help reverse skin thinning by working with the CD44 receptor.