January 2014 in “Hair transplant forum international” Hair follicle cloning is possible but faces many challenges before it can replace traditional hair transplants.
January 2022 in “Stem cell biology and regenerative medicine” Lymphatic vessels help hair follicles regenerate by interacting with stem cells.
165 citations,
June 2007 in “European Journal of Cell Biology” Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
64 citations,
January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Human stem cells can help form hair follicles in mice.
39 citations,
April 1992 in “Development” Both cell and non-cell parts are important for rat whisker follicle regrowth.
28 citations,
August 2015 in “Journal of Drug Targeting” The new CoQ10 gel protects mouse skin better against aging from UV light than the old gel.
17 citations,
September 2016 in “Stem cells translational medicine” Using bioreactors, scientists can grow more skin stem cells that keep their ability to regenerate skin and hair.
13 citations,
November 2021 in “Biomedicines” Plasma-activated liquid can kill harmful cells, speed up wound healing, and potentially treat cancer without damaging healthy cells.
9 citations,
August 2022 in “Frontiers in Pharmacology” Kangfuxin (KFX) extract speeds up wound healing and improves skin regeneration.
7 citations,
August 2022 in “Experimental dermatology” Blocking YAP/TAZ could be a new way to treat skin cancer.
4 citations,
March 2022 in “Pharmaceutics” Regenerative cellular therapies show promise for treating non-scarring hair loss but need more research.
3 citations,
September 2017 in “Stem cell investigation” PDGF signaling is crucial for maintaining fat stem cells in the skin, and its level of activation can either preserve these cells or cause fibrosis.
2 citations,
January 2023 in “BioMed Research International” The secretome from mesenchymal stromal cells shows promise for improving facial nerve injury treatment.
1 citations,
January 2024 in “Microorganisms” Mice with a virus similar to COVID-19 had skin damage, but a special treatment helped repair it.
1 citations,
January 2024 in “Cellular & Molecular Biology Letters” Adipose-derived stem cells help heal burns but need more research.
1 citations,
December 2022 in “Pharmaceutics” Finasteride-loaded microemulsions can effectively enhance skin delivery for treating hair loss.
May 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” KAP-depleted hair causes less immune response and is more biocompatible for implants.
March 2024 in “Biomedicines” Mesenchymal stem cells show promise for effective skin repair and regeneration.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Aged individuals heal wounds less effectively due to specific immune cell issues.
May 2023 in “Scientific Reports” The seed extract of Lepidium sativum L. can potentially treat hair loss, showing effects similar to 5% minoxidil.
Androgenetic alopecia, or hair loss, is caused by a mix of genetics, hormones, and environment, where testosterone affects hair growth and causes hair to become smaller and grow for a shorter time.
401 citations,
January 2013 in “Postepy Dermatologii I Alergologii” The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.
34 citations,
June 2005 in “Developmental dynamics” Runx3 helps determine hair shape.
2 citations,
June 2020 in “Journal of Investigative Dermatology” 3D imaging of skin biopsies offers better accuracy but is time-consuming and can't clear melanin.
1 citations,
April 2022 in “Regenerative Therapy” Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.
27 citations,
August 2021 in “Journal of Autoimmunity” Human dermal γδT-cells respond to stress in hair follicles, contributing to hair loss.
July 2024 in “Behavioural Brain Research” Long-term finasteride treatment reduces depression and brain issues in obese male rats.
April 2023 in “Journal of Investigative Dermatology” The research updated the skin cell profile, finding new skin cell markers and showing fibroblasts' key role in skin health.
May 2022 in “The journal of immunology/The Journal of immunology” FOXN1 is crucial for thymus development and immune response in Xenopus laevis.
318 citations,
January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.