Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that in murine dermis, fibroblast state switching between proliferation and ECM deposition plays a crucial role in tissue architecture and wound healing.

Hair follicle stem cells help maintain skin health after injury.

This review summarizes the latest progress and challenges in skin organoid research, emphasizing advancements in organoid construction, applications in disease modeling, and factors affecting tissue maturation, while noting barriers such as vascularization and neural integration that hinder clinical translation.

This review highlights the potential of adipose-derived mesenchymal stem cells as a cost-effective solution for tissue restoration and regeneration in ophthalmic and oculoplastic surgeries, addressing unmet needs in reconstructive procedures.

This study observed that keratin sponges showed comparable biocompatibility to a commercial positive control in mice, but keratin gels had slightly inferior biocompatibility.

This review discusses the role of epidermal and other adult stem cells in skin repair, focusing on their potential therapeutic applications for non-healing wounds and other skin disorders, but reports no new research results.

This review discusses the role of fibroblast growth factors and their receptors in maintaining and repairing epithelial tissues, highlighting their importance in epithelial homeostasis and response to injuries without reporting new clinical results.

This review explores the potential of neuro-driven hydrogels for skin and nerve regeneration, integrating biochemical cues and advanced technologies like AI for personalized wound healing, but notes the need for further validation and trials before clinical use.

This research review observed that topical hormone replacement therapy, particularly estradiol and estradiol-testosterone combinations, significantly increased Type I and III collagen synthesis in the skin of postmenopausal women, suggesting benefits against collagen loss-related skin aging effects such as reduced elasticity and increased dryness.

This review highlights the development and assessment of human-relevant models for cutaneous wound healing, emphasizing that a combination of systems, such as organoid platforms and skin-on-a-chip systems, is necessary to overcome limitations of traditional methodologies and address chronic wound challenges.

This study found that EGCG improved the integrity of skin grafts during cryopreservation, suggesting its potential usefulness for skin preservation, though the exact mechanism remains unclear.

Collagen XVIII is crucial for maintaining tissue structure and function in the brain, kidneys, and hair.

This study found that matriptase, a membrane serine protease, is crucial for maintaining multiple types of epithelial tissues in mice, with its absence leading to severe organ dysfunction and increased permeability.

In this study, researchers using live mice observed that oncogenic Kras mutation disrupts hair follicle architecture by sustaining ERK signal activation, which affects stem cell behavior and tissue integrity.

This research found that immobilizing type I atelocollagen onto artificial hair significantly improved the adhesion and long-term fixation of the hairs in the human scalp, indicating high biosafety and enhanced tissue integration.

This article reviews the mechanisms controlling long bone growth and suggests that new research approaches are needed to explore the role of extrinsic signals and tissue interactions.

This study identified increased expression of ACAA1 and its regulation by hsa-miR-1343-3p, linking androgenetic alopecia to lipid metabolism pathways, particularly through PPAR signaling, in scalp tissues.

In this study, researchers found that eccrine sweat glands in human scalp skin are morphologically integrated into the pilosebaceous unit, suggesting they form a common homeostatic tissue environment with adjacent structures.

In diabetic mice, this study reported that the multifunctional hydrogel CPGel achieved complete wound closure in 21 days, showing promise in improving chronic wound healing through antibacterial, antioxidative, and tissue regeneration properties.

In this study, researchers developed a versatile sprayable hydrogel that promotes wound healing in mice by facilitating rapid gelation, reducing inflammation, and accelerating tissue regeneration, with potential applications in chronic wound treatment and beyond.

This review summarizes how single-cell omics technologies have advanced understanding of cellular regulatory programs in sheep and goats, but highlights limitations in genomic annotation and integration with population genetics for molecular breeding.

In this review, the authors discuss how SOX9 functions as a key regulator of epithelial cell fate and tissue repair, suggesting its role in integrating environmental signals, which could inform regenerative medicine approaches despite potential risks like fibrosis and cancer.

This review found significant progress in 3D bioprinting for surgery, noting advances in creating complex tissue constructs, while highlighting ongoing challenges like vascularization and integration with host tissue, emphasizing the need for further research and regulatory development.

This paper reviews the state of knowledge on injectable cryogels, highlighting their unique properties such as shape-memory and mechanical integrity, which allow for minimally invasive delivery via needles and potential applications in oncology and regenerative medicine.

This study introduced a bioengineering platform that creates early-stage hair peg-like structures within tissue-engineered skin substitutes by integrating human keratinocytes and dermal papilla cells with laser-micropatterned collagen scaffolds, providing a foundation for future appendage-inclusive skin regeneration efforts.

This study highlighted the significance of integrating single-cell RNA sequencing with spatial transcriptomics for improving cell-type identification in human skin, emphasizing the need for a comprehensive cell atlas.

This source reviews the potential of 3D printing, biomaterials, and smart sensors in tissue engineering, noting their application in creating artificial membranes for skin and tissue regeneration and assessing their strengths and limitations for wound dressing development and disease modeling.

This review presents an overview of the integrated organ systems involved in wound healing and reports no new findings; the authors emphasize the roles of blood coagulation, immune response, and cellular mechanisms in tissue repair.

This study observed that keratose, derived from human hair, integrated well in mouse tissue and remodeled with collagen, suggesting potential as a non-toxic biomaterial for regenerative applications.

This study reviewed recent advances in regenerative technologies for aesthetic and reconstructive medicine and found that adipose-derived stem cells and platelet-rich plasma are well-established for tissue repair due to their safety and effectiveness, while emerging technologies like exosome-based therapies hold future potential.