26 citations,
December 2016 in “Pharmacology & Therapeutics” New drugs for heart disease may be developed from molecules secreted by stem cells.
25 citations,
September 2018 in “Molecular Biology of the Cell” Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.
25 citations,
April 2012 in “Acta Biomaterialia” Using certain small proteins with a growth factor and specific materials can increase the creation of neurons from stem cells.
24 citations,
November 2016 in “Cell death and disease” Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.
24 citations,
September 2014 in “Drug Delivery” Using microneedles before applying eflornithine cream can make it more effective at stopping hair growth.
23 citations,
June 2017 in “Drug Design Development and Therapy” Cyclodextrins improve finasteride's solubility and bioavailability for hair loss treatment.
22 citations,
March 2021 in “Journal of Cutaneous Medicine and Surgery” Ultrasound is a useful, non-invasive tool in dermatology for diagnosing skin conditions and guiding treatments, but it has some limitations.
22 citations,
September 2018 in “Medical Clinics of North America” Facial aging is caused by natural processes and external factors, and can be managed with preventative measures and a variety of treatments tailored to individual needs.
22 citations,
August 2017 in “Stem cells and cloning” Stem cell technologies and regenerative medicine, including platelet-rich plasma, show promise for hair restoration in treating hair loss, but more research is needed.
20 citations,
February 2002 in “Expert Opinion on Therapeutic Patents” New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
19 citations,
August 2019 in “Expert Opinion on Therapeutic Targets” New treatments for hair loss may target specific pathways and generate new hair follicles.
19 citations,
December 2015 in “Journal of Materials Chemistry B” Scientists have created a method to deliver specific cells that can regenerate hair follicles, potentially offering a new treatment for hair loss.
19 citations,
May 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” The type 3 IP3 receptor is important for controlling hair loss and growth.
18 citations,
June 1999 in “Statistical Methods in Medical Research” The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.
18 citations,
June 1998 in “Circulation” Mild essential fatty acid deficiency can cause health issues and is worsened by low-fat diets.
17 citations,
January 2019 in “International journal of biological sciences” Researchers used CRISPR/Cas9 to create a goat with a gene that increased cashmere production by 74.5% without affecting quality.
17 citations,
December 2014 in “Cell Stem Cell” Intravital imaging helps us better understand stem cells in their natural environment and could improve knowledge of organ regeneration and cancer development.
16 citations,
January 2016 in “International Journal of Medical Sciences” Wnt5a slows down hair growth by blocking a specific pathway during hair regeneration.
15 citations,
May 2005 in “Seminars in Plastic Surgery” The document concludes that hair follicular unit transplantation is an effective method for eyebrow and eyelash reconstruction, with patients happy despite needing regular trimming.
14 citations,
August 2018 in “Frontiers in Cellular and Infection Microbiology” Dengue virus can infect human hair follicle cells and may cause hair loss.
14 citations,
January 2001 in “Current Treatment Options in Oncology” Treat limited stage small cell lung cancer with chemotherapy and radiation, and consider preventive brain radiation for better survival chances.
13 citations,
January 2022 in “Stem cell reviews and reports” Mouse stem cells from hair follicles can improve wound healing and reduce scarring.
13 citations,
December 2020 in “Dermatologic Therapy” Sebaceous glands in our skin, developing during pregnancy and active in puberty, produce sebum for skin lubrication, temperature control, and fighting germs, also help in hormone regulation, and their dysfunction can cause conditions like acne and hair loss.
13 citations,
January 2020 in “Scientific Reports” The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.
13 citations,
January 2017 in “Molecules” Compounds from Alpinia zerumbet may help with hair regrowth and cancer treatment by targeting PAK1.
13 citations,
November 2013 in “Journal of Endocrinology/Journal of endocrinology” Vitamin D receptor helps control hair growth genes in skin cells.
12 citations,
October 2017 in “Journal of Cosmetic Dermatology” Combining plasma rich in growth factors with hair transplant surgery may lead to faster recovery and better outcomes for hair loss treatment.
11 citations,
December 2011 in “Biochemical journal” Neurotrophin-4 increases calcium current in specific mouse neurons through the PI3K pathway.
10 citations,
February 2019 in “Toxicological Sciences” Finasteride exposure affects gene expression and anogenital distance in male rat fetuses.
10 citations,
May 2018 in “Cell death discovery” HSP90 and lamin A/C are crucial for hair growth and could be targets for treating hair loss.