15 citations,
February 2009 in “Cell Stem Cell” The document concludes that certain chemicals can help maintain stem cell pluripotency and that understanding cell states is crucial for tissue regeneration.
8 citations,
June 2001 in “International Journal of Cosmetic Surgery and Aesthetic Dermatology” Use shallow cuts, small tissue removal, careful suturing, and keep the area moist to reduce scarring in hair transplants.
4 citations,
August 2022 in “International Journal of Molecular Sciences” Human foreskin does not show aging or reduced cell growth after radiation, and H2A.J is not a good marker for radiation-induced aging.
3 citations,
April 2009 in “PubMed” Melatonin may protect rat hair follicles from damage caused by oxidative stress after a burn.
1 citations,
January 2024 in “International journal of molecular sciences” TRPV4 helps cells repair tissue and reduce scarring by controlling calcium levels.
1 citations,
December 2022 in “Frontiers in Immunology” Tissue environment greatly affects the unique epigenetic makeup of regulatory T cells, which could impact autoimmune disease treatment.
September 2024 in “Journal of Cutaneous and Aesthetic Surgery” A young man with severe neck and beard burns was successfully treated, restoring neck movement and improving skin appearance.
January 2024 in “Defence life science journal” Light therapy can help heal soft tissue injuries and reduce pain and inflammation.
January 2008 in “The Year book of dermatology” After skin injury, adult mice can grow new hair follicles, and this process can be increased or stopped by manipulating Wnt signals.
759 citations,
February 2009 in “Current Biology” Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
112 citations,
January 2014 in “Molecular and cellular therapies” Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
61 citations,
April 2023 in “Bioactive Materials” Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
39 citations,
April 2019 in “Journal of Biomaterials Science, Polymer Edition” RADA16 is a promising material for tissue repair and regenerative medicine but needs improvement in strength and cost.
39 citations,
September 2011 in “Tissue Engineering Part B-reviews” Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.
20 citations,
June 2020 in “Stem Cell Research & Therapy” Using stem cells from fat tissue can significantly improve wound healing in dogs.
13 citations,
August 2018 in “Facial Plastic Surgery Clinics of North America” Adipose tissue shows promise for hair regrowth, but more research is needed to confirm best practices and effectiveness.
12 citations,
March 2018 in “Bioengineering” The document concludes that products like PRP and PRF show promise for tissue healing, but evidence of their effectiveness is inconsistent.
9 citations,
March 2023 in “Biomimetics” New materials that better mimic natural skin structure could improve healing, especially for chronic wounds.
9 citations,
February 2021 in “Frontiers in Cell and Developmental Biology” Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.
9 citations,
July 2007 in “Journal of Investigative Dermatology” Claudin expression changes help the skin respond to injury.
5 citations,
May 2021 in “EMBO journal” Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.
5 citations,
March 2019 in “Experimental dermatology” Activating TLR3 may help produce retinoic acid, important for tissue regeneration.
4 citations,
January 2022 in “Life” Tissue engineering could be a future solution for hair loss, but it's currently expensive, complex, and hard to apply in real-world treatments.
3 citations,
August 2011 in “InTech eBooks” The document concludes that skin grafts are essential for repairing tissue loss, with various types available and ongoing research into substitutes to improve outcomes and reduce donor site issues.
2 citations,
November 2022 in “Scientific reports” Using gelatin sponges for deep skin wounds helps bone marrow cells repair tissue without scarring.
2 citations,
September 2018 in “Tissue Engineering Part A” Xeno-free three-dimensional stem cell masses are safe and effective for improving blood flow and tissue repair in limb ischemia.
1 citations,
March 2024 in “Nanomaterials” Biomimetic scaffolds are better than traditional methods for growing cells and could help regenerate various tissues.
July 2022 in “Biomedicines” 4-Aminopyridine improves skin wound healing and tissue regeneration by increasing cell growth and promoting nerve repair.
January 2018 in “Stem cells in clinical applications” Exosomes show promise for tissue repair and regeneration with advantages over traditional cell therapies.
Tissue from dog stem cells helped grow hair in mice.