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The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Blocking YAP/TAZ could be a new way to treat skin cancer.

Bacteria can help skin regenerate through a process called IL-1β signaling.

Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.

DA-9401 helps protect rat testis from finasteride damage.

Drugmakers are optimistic about targeting the Wnt pathway for new treatments despite past challenges.

The stiffness of a wound affects hair growth during healing, with less stiff areas growing more hair.

FAPD and possibly CCCA may be AGA subtypes, and treatments combining antiandrogens, hair growth agents, hair transplants, and anti-inflammatories could be effective.

Acne patients have higher skin mTORC1 activity, which is reduced by isotretinoin treatment.

The authors maintain that shorter androgen receptor alleles may lead to milder COVID-19 by positively affecting the immune response, not due to changes in testosterone levels or activity.

Different drugs are used to manage breeding, prevent or end pregnancy, and treat reproductive issues in dogs and cats.

The Hairless gene is crucial for healthy skin and hair growth.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

The drugs finasteride and dutasteride reduce low-grade prostate cancers but may double the risk of high-grade cancers.

Personalized medicine is important for treating skin disorders, with new treatments and connections to hormones and genetics being explored.

Antiandrogens are used to manage polycystic ovary syndrome by reducing androgen levels or controlling their effects, often combined with lifestyle changes and other treatments.

Nitric oxide is important for skin functions and both helps protect against and contributes to skin inflammation and sensitization.

The Wnt/β-catenin signaling pathway is important for skin wound healing and affects inflammation, cell growth, and other healing processes.

Targeting and modifying the stem cell niche can improve regenerative therapies.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Cimicifuga racemosa extract may help prevent and treat prostate issues by inhibiting 5α-reductase.

WNT signaling is crucial for skin development and healing.

Minoxidil does not work to inhibit lysyl hydroxylases in newborn mouse lungs.

Growth factor treatments are increasingly used in medicine but require more research to fully understand their mechanisms.

Frontal fibrosing alopecia is linked to increased immune system activity and reduced stem cells, suggesting early treatment targeting this pathway might prevent hair follicle damage.

Some medications can cause hair loss, but stopping the drug usually leads to recovery within 3 months.