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Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Plasmacytoid dendritic cells are a key factor in causing hair loss in alopecia areata and could help differentiate it from other hair loss conditions.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

After skin is damaged, noncoding dsRNA helps prostaglandins and Wnts work together to repair tissue and promote hair growth.

New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

New drugs for rheumatoid arthritis show improvement but have side effects and are not a cure.

Scientists made structures that look like human hair follicles using stem cells, which could help grow hair without using actual human tissue.

Ruxolitinib treatment may cause eyelash growth.

Cells from certain embryo parts can induce head formation in another embryo, involving complex signaling pathways.

Blocking a specific enzyme can reduce the negative impact of stress hormones on hair growth cells.

New therapies show promise for wound healing, but more research is needed for safe, affordable options.

Eclipta alba extract could be a promising natural treatment for hair loss.

A substance called prostaglandin D2 is linked to stopping hair growth in men with common baldness.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Stem cell self-renewal is complex and needs more research for full understanding.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Apoptosis is crucial for healthy skin and treating skin diseases.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.