research A New 3D Skin Model Containing Autologous Immune Cells Reconstructed by Tissue Engineering
Researchers developed a 3D skin model with its own immune and blood vessel cells to better understand skin health and disease.
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research Skin Tissue Engineering: Potential of Stem Cell Biology and Skin Morphogenesis
Improved understanding of stem cell mechanisms can enhance skin tissue engineering.
research The De Novo DNA Methyltransferase DNMT3A Is Required for Epidermal Homeostasis
DNMT3A is crucial for healthy skin and hair growth.
research Live-Imaging the Interface Between Homeostasis and Cancer Initiation
Mutant cells in hair follicles are influenced by their location and interactions with surrounding cells.
research The Localization of Cytokeratin 19 and Vimentin in Sprague Dawley Albino Rat Skin Tissue
CK19 and Vimentin are proteins found in rat skin that help with skin renewal and maintaining cell structure.
research Skin Cyst: A Pathological Dead-End With a New Twist of Morphogenetic Potentials in Organoid Cultures
Skin cysts might help advance stem cell treatments to repair skin.
research Cutaneous Epithelial Stem Cells
Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.
research Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications
Stem cells are crucial for skin repair and new treatments for chronic wounds.
research Dermal Niche Signaling and Epidermal Stem Cells
Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
research Nerve Growth Factor and Burn Wound Healing: Update of Molecular Interactions With Skin Cells
Nerve growth factor helps improve healing time and scar quality in burn wounds.
research MiRNA in Regulation of Skin and Hair Follicle Development
miRNAs are key in skin and hair growth and maintenance.
research Anatomy and Physiology of the Skin
The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
research Revisiting the Role of Melatonin in Human Melanocyte Physiology: A Skin Context Perspective
Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.
research Fibroblasts: Immunomodulatory Factors in Refractory Diabetic Wound Healing
Fibroblasts are important in healing diabetic wounds, but high sugar levels can harm their function and slow down the healing process.
research PLCD1 and Pilar Cysts
The research linked PLCD1 gene variants to the development of trichilemmal cysts.
research Minireview: Vitamin D Receptor: New Assignments for an Already Busy Receptor
The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.
research Impaired Wound Healing in Transgenic Mice Overexpressing the Activin Antagonist Follistatin in the Epidermis
Overexpressing follistatin in mice delays wound healing and reduces scar size.
research Skin Steroidogenesis in Health and Disease
The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
research Impact of Metformin and Rosiglitazone Treatment on Glucose Transporter 4 mRNA Expression in Women with Polycystic Ovary Syndrome
Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.
research Tregs: Where We Are and What Comes Next?
The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.
research Skin-Infiltrating CD4+ Lymphoma Cells Depend on Hair Follicle-Derived IL-7
Hair follicles produce IL-7, which is essential for certain skin lymphoma cells to survive.
research RANKL Induces Organized Lymph Node Growth by Stromal Cell Proliferation
RANKL causes lymph nodes to grow by making certain cells multiply.
research Novel Insights Into the Molecular Mechanisms Underlying Generalized Glucocorticoid Resistance and Hypersensitivity Syndromes
Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.
research Greasy Hair Against Obesity: TSLP-Induced Sebum Production Reduces Fat
Increasing sebum production might help reduce fat and improve metabolism.
research Regeneration of Dermis: Scarring and Cells Involved
Different fibroblasts play key roles in skin healing and scarring.
research Hairless: A Nuclear Receptor Corepressor Essential for Skin Function
The Hairless gene is crucial for healthy skin and hair growth.
research Building and Maintaining the Skin
Three types of stem cells help maintain and repair skin, responding to health and environmental changes.
research Autologous Cell Therapy for Aged Human Skin: A Randomized, Placebo-Controlled, Phase I Study
RCS-01 therapy is safe and may improve skin structure by affecting gene expression.
research A Review of Adipocyte Lineage Cells and Dermal Papilla Cells in Hair Follicle Regeneration
Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.
research Murine Sebaceous Gland Homeostasis Requires Intact Cutaneous Innervation in a Hair Cycle-Dependent Context
Mouse skin glands need healthy nerves to grow properly during hair growth phases.