January 2012 in “Jaypee Brothers Medical Publishers (P) Ltd. eBooks” Various surgical methods for hair restoration, like scalp reconstruction and tissue expansion, have been developed, but follicular unit transplant remains the most common procedure for correcting pattern baldness.
September 2004 in “Atlas of the Oral and Maxillofacial Surgery Clinics” This article provides an overview of hair restoration surgery options and applications for cosmetic and reconstructive hair deformity treatment and reports no clinical results.
October 1987 in “Clinics in Dermatology” This review discusses scalp reduction surgery for male-pattern baldness, highlighting its effectiveness in reducing bald areas when hair transplantation alone is not sufficient, without increasing total hair volume.
31 citations
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March 2009 in “Archives of Facial Plastic Surgery” This retrospective study found that a hairline-lowering technique effectively advanced the female hairline by an average of 2.1 cm with high patient satisfaction and minimal complications over 20 years.
6 citations
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July 2017 in “Clinics in Plastic Surgery” This article reviews the management of head and neck burns across different phases but presents no new clinical results.
October 2019 in “The Egyptian Journal of Hospital Medicine” In this study, both hair transplantation and skin expansion were found effective for treating cicatricial alopecia, with transplantation being preferable for adults with smaller areas and skin expansion suited to younger patients with larger areas.
July 1998 in “Dermatologic Surgery” Various techniques and tools for hair restoration were presented in 1998, including a mathematical model for donor area, use of lasers in surgery, methods for controlling grafted hair direction, and ways to increase graft yield. Satisfaction rates were around 39%, and studies showed trauma and dehydration can damage hair follicles.
July 2007 in “Clinical Risk” A woman got severe scalp burns from a salon's improper hair bleaching treatment.
7 citations
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April 1994 in “Archives of Otolaryngology-head & Neck Surgery” This article discusses scalp tissue expansion as a superior reconstructive option for large defects over traditional skin grafts and flap methods, but reports no new clinical outcomes.
January 2024 in “Burns and trauma” In a rat scalp expansion model, this study found that activating autophagy with rapamycin enhanced skin regeneration during tissue expansion by increasing expanded skin area, epidermis and dermis thicknesses, cell proliferation, angiogenesis, and other regenerative factors, whereas blocking autophagy reversed these effects.
140 citations
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December 2017 in “Journal of Controlled Release” This study reviews the evolution and modifications of microneedle drug delivery systems, initially designed for percutaneous use, now expanded for targeting a variety of tissues and organs such as ocular, oral mucosal, and gastrointestinal, suggesting widespread future applicability.
November 2025 in “Communications Materials” This research demonstrated that transforming pomelo peel into expanded sponges and carbonized aerogels can accelerate hemostasis and enhance healing in diabetic wounds while eradicating bacterial biofilms, offering an eco-friendly solution for wound care from agricultural waste.
March 2026 in “Akdeniz Medical Journal” This review focuses on the role of exosomes in diagnosing and treating various dermatological diseases, emphasizing their potential to promote skin regeneration, improve cosmetic outcomes, and modulate immune-related conditions, with the anticipation of expanded future applications.
44 citations
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January 2019 in “Journal of Translational Medicine” This study found that macrophages are crucial for skin regeneration during tissue expansion, as their depletion in rats led to inhibited skin growth and reduced secretion of key growth factors.
27 citations
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October 2020 in “Biomedicine & Pharmacotherapy” This study found that transplanting hair follicle bulge-derived stem cells in rats enhanced skin regeneration during expansion by differentiating into several skin-related cells and increasing the expression of growth factors.
25 citations
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January 2001 in “Facial Plastic Surgery” This article reviews the history, methods, and complications of tissue expansion and serial excision for scar revision in the head and neck, and reports no new findings.
December 2016 in “Journal of Pakistan Association of Dermatology” In this study, tissue expansion was identified as a safer initial procedure before hair transplantation for patients with large scalp defects, with the majority of participants having postburn scars and a mean expansion time of 33.6 days.
40 citations
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January 2009 in “Skin Pharmacology and Physiology” This review discusses the potential use of cultured primary fetal cells from a single organ donation to produce therapeutic products, emphasizing the need for process consistency and safety verification, but reports no clinical results.
6 citations
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February 2010 in “Biotechnology and bioprocess engineering” This study investigated optimizing the differentiation process of UC-MSCs into dermal papilla-like tissues for potential hair follicle therapy and highlighted the potential to reduce associated costs by evaluating cell density and growth factors.
August 2026 in “Transplantation and Cellular Therapy” This study found that serum-free expanded hair follicle mesenchymal stem cells (hfMSCs), derived from hair plucking, significantly improved cartilage repair in a murine model despite minimal engraftment, suggesting their effectiveness through a paracrine mechanism.
49 citations
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March 2019 in “Journal of Investigative Dermatology” This review discusses dermal white adipose tissue's roles in skin immunity, highlighting its antimicrobial function and interactions with other immune cells, but reports no new clinical results.
92 citations
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September 2015 in “Journal of Lipid Research” This review discusses the roles of dermal white adipose tissue (dWAT) as an insulator, antibiotic, and regenerative tissue, highlighting its importance in systemic metabolism and immune function, but reports no new clinical results.
January 2015 in “D-Scholarship@Pitt (University of Pittsburgh)” This dissertation investigated barriers to clinical translation of adipose-derived mesenchymal stem cell-based vascular grafts, highlighting issues with thrombosis in diabetic patients and proposing alternative cell sources to improve applicability.
27 citations
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February 2023 in “Frontiers in Cell and Developmental Biology” This review discusses the expanded understanding of WNT10B's role in various tissues and diseases over the past decade, emphasizing its genetic correlations and potential therapeutic implications, but reports no new clinical results.
November 2025 in “Advanced Therapeutics” This review examines platelet-rich plasma therapy's multidisciplinary applications in regenerative medicine and discusses preparation challenges but presents no new clinical results.
July 2025 in “Cosmoderma” This review discusses the various applications of platelet-rich plasma in dermatology, particularly its potential in esthetic dermatology and hair and scalp conditions, but reports no new clinical findings.
10 citations
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April 2007 in “Aesthetic Plastic Surgery” This study demonstrated the feasibility of a new patient-controlled method for tissue expansion that achieved full expansion in about 3 weeks with minimal complications after mastectomy.
June 1997 in “The American Journal of Cosmetic Surgery” This article discusses the use of scalp stretching techniques to enhance donor hair supply for hair restoration, but it reports no new clinical findings.
10 citations
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December 1997 in “Plastic and Reconstructive Surgery” This text provides contact information and no new research findings are reported.
63 citations
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September 2009 in “Regenerative Medicine” This study developed a method for expanding human dermal papilla cells in vitro while maintaining their ability to induce hair growth, advancing the potential for follicular cell implantation as a treatment for hair loss.