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Prostasin has two roles in skin: one for normal skin development without needing activation, and another for proper hair growth that requires activation.

Phospholipase A2 enzymes play key roles in skin health and disease.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

The document discusses male and female pattern hair loss, its diagnosis methods, FDA-approved treatments like finasteride and minoxidil, their side effects, and the role of lifestyle changes.

Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.

The hydrogel with silver and ibuprofen promotes wound healing and fights infection.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Placenta products might help with hair loss, but more research is needed.

Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.

Many popular skincare products claim to prevent aging but lack strong evidence to prove their effectiveness and safety.

Thallium is highly toxic, causing severe health issues, and Prussian blue is the best antidote.

Most skin issues were due to COVID-19, with some caused by vaccines or treatments, and were categorized into five types.

New tools show that in fish, NPY increases feeding and somatostatin decreases it.

Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.

Finasteride and dutasteride are effective for male hair loss and enlarged prostate but may cause reversible sexual side effects.

Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.

Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.

Porcine skin is very similar to human skin, making it a useful model for research.

Vitamin D is important for bones, hair, blood pressure, and breast development.

Melatonin helps regulate sleep and may aid in treating various health issues.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.

Scalp itching is common and hard to diagnose due to the complex nerve structure of the scalp.

Minoxidil 2% and 5% are common treatments for female pattern hair loss, with other options including anti-androgens, oral contraceptives, and hair transplantation.

Women may need different blood pressure guidelines than men for heart disease prevention.

CD8+ T cells are involved in alopecia areata and may cause disease relapse.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Muscles can make their own androgens, which may help muscle growth.