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The document says that understanding the causes of PCOS is important for treatment, especially in distinguishing the syndrome from just having cystic ovaries, and that losing weight is key for obese women with PCOS.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Long COVID patients may have hormonal imbalances linked to their symptoms.

Allopregnanolone increases growth and changes gene activity in human brain cancer cells.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

Some plants with flavonoids may help treat hair loss and promote hair growth.

Finasteride improves hair growth and reduces hirsutism in women, but side effects and optimal dosages need further research.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Taking finasteride for benign prostate hyperplasia may increase the risk of osteoporosis, especially at higher doses.

Taking oral testosterone with finasteride or dutasteride doubles testosterone levels, and food slightly affects it.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Detailed patient history and physical exams are crucial for diagnosing hair loss.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Dutasteride works better than finasteride for hair loss, with both being safe to use.

Obesity is linked to various skin disorders, which can help with early diagnosis and prevention of long-term health issues.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

Over 50% of women over 50 experience hair loss, with minoxidil being the only proven effective treatment.

Adrenal glands delay the start of winter fur growth in mink.

COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.

α-Blockers and 5-ARIs for BPH can cause sexual dysfunction, including erectile and ejaculatory issues.

α-spinasterol from Melandrium firmum can help reduce prostate enlargement.

ACBP is essential for healthy skin and fur by maintaining the skin's barrier function.

HIV-1 may cause increased stem cell death in hair follicles, leading to hair loss.

Finasteride doesn't affect erections much, but may decrease libido in men.