4 citations
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October 2024 in “International Journal of Molecular Sciences” This study found that chitosan nanoparticle-encapsulated Cordyceps militaris significantly reduced inflammation and oxidative stress in particulate matter-exposed mice, suggesting potential use for managing lung inflammation.
April 2026 in “Research Square” This study found that COVID-19 infection disrupts spermatogenesis, alters testicular cell populations, and may impact male fertility by causing long-term changes in testicular function and reduced sperm quality, as observed even in patients who have recovered from the acute phase of the infection.
January 2024 in “Wiadomości Lekarskie” This paper reviews current cell therapies in medicine, highlighting hematopoietic stem cell transplants as a foundational success and the growing application of genetically modified cells like CAR-T and mesenchymal stem cells for various diseases, including blood disorders and autoimmune conditions.
July 2017 in “Cancer Research” This study identified a radio-resistant population of Krt15+ stem cells in the mouse small intestine that can initiate tumors, suggesting potential targets for colon cancer therapy.
1 citations
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September 2023 in “Research Square (Research Square)” This study found that heart-inspired hollow hydrogel-based scaffolds enhanced regenerative capability in osteoporotic bone defects and increased cell number when using a mechanical-assisted post-bioprinting strategy.
This study reviewed chitosan composites, specifically those with silver or zinc oxide nanoparticles, highlighting their enhanced antimicrobial efficacy and potential biomedical applications despite pure chitosan's limitations such as pH sensitivity and poor solubility.
January 2016 in “Munich Personal RePEc Archive (Ludwig Maximilian University of Munich)” This study demonstrated that a light-activated RNAi approach using hollow gold nanoshells effectively targets human prostate cancer cells with reduced off-target toxicity and material use compared to standard methods.
November 2023 in “International Journal of Medical Case Reports and Reviews” This review discusses the potential and current applications of platelet-rich plasma in otolaryngology and reports no new clinical results; the authors note varying evidence for its effectiveness across medical conditions.
124 citations
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February 2018 in “Nature Reviews Genetics” This review covers recent findings on stem cell plasticity under normal and cancerous conditions but presents no new experimental results, highlighting implications for regenerative medicine and cancer treatments.
54 citations
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August 2019 in “Bioscience trends” This review discusses the potential of stem cell secretome in regenerative medicine and suggests that its paracrine effects, rather than direct cell replacement, may drive therapeutic benefits.
30 citations
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August 2016 in “Advances in radiation oncology” This study developed a mouse model for radiation cystitis that mimics human pathology and found that radiation exposure leads to increased urinary frequency and long-term weakening of urothelial integrity.
27 citations
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April 2017 in “Journal of Investigative Dermatology” The researchers reported that noncoding double-stranded RNA promotes wound-induced hair neogenesis in mice by modulating prostaglandin and Wnt levels.
9 citations
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July 2011 in “Cytokine” This study suggests that finasteride treatment may improve pulmonary immune response in mice following trauma and sepsis, indicating potential as a therapeutic option after major trauma.
6 citations
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January 2005 in “Biology of Blood and Marrow Transplantation” This article reviews various models of graft-versus-host disease, highlighting the complexity of its mechanisms and the challenges in interpreting histopathologic data; it reports no new results.
3 citations
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March 2024 in “Viruses” This study found that γδ T cells in the skin contribute to wound healing after vaccinia virus infection by promoting cytokine and growth factor induction, without affecting virus replication control.
18 citations
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August 2023 in “Journal of Cell Science” This review explores how metabolic changes drive cellular quiescence and considers potential applications in cancer treatment by manipulating these processes.
13 citations
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March 1999 in “Biochemical Journal” In this study, transgenic mice overexpressing the SSAT gene were highly sensitive to polyamine analogues, leading to severe liver changes and high mortality rates after treatment.
10 citations
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June 2023 in “Preprints.org” This review discusses transdermal drug delivery using hydrogel-forming microneedles and highlights their potential and challenges for clinical application, but it reports no new clinical findings.
10 citations
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September 2022 in “Journal of Biophotonics” This study analyzed clinical and histological reports and concluded that blue light therapy is safe for human skin, with potential photoprotective effects against UV irradiation due to its impact on skin pigmentation mediated by Opsin-3.
January 2024 in “Wiadomości Lekarskie” This study highlights the role of innate immunity and purinergic signaling in regulating hematopoiesis and hematopoietic stem/progenitor cell specification. The researchers observed that these ancient pathways operate both paracrinally and autocrinally within HSPCs, maintaining their developmental function throughout evolution.
This review discusses Limbal Mesenchymal Stem Cell Secretome therapy for ocular chemical injuries, noting its potential in reducing inflammation and corneal opacity, but reports no new clinical results.
December 2021 in “Signal transduction and targeted therapy” This study found that serum levels of NF-L and GFAP decreased but tau protein levels did not change in anorexia nervosa patients after short-term partial weight restoration.
October 2021 in “Nepal journal of dermatology, venereology & leprology” This review discusses the diverse roles and potential skin health benefits of melatonin, highlighting its anti-inflammatory, antioxidant, and protective effects but reports no new clinical results.
June 2021 in “EBioMedicine” This paper reports no new results; it addresses the effects of Dutasteride on testosterone and DHT in men, and discusses the implications for androgen deprivation and COVID-19 outcomes.
275 citations
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March 1999 in “Journal of The American Academy of Dermatology” This review elaborates on the skin side effects of chemotherapy and emphasizes identifying and managing both common and life-threatening skin reactions, without presenting new clinical findings.
82 citations
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June 2020 in “Inflammation Research” This review discusses the complex pathophysiological and clinical aspects of COVID-19, including dermatological findings and their association with SARS-CoV-2 infection but reports no new clinical results.
70 citations
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June 2017 in “Nature Communications” This study introduced a new technique, 2Phatal, enabling precise apoptotic cell ablation in living animals, revealing unique cell-type differences in apoptosis-related dynamics.
25 citations
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June 2024 in “Pharmaceutics” This review highlights the potential of scaffold-based drug delivery systems to revolutionize oral cancer treatment by enhancing targeted and localized drug administration, reducing systemic side effects, and providing environments conducive to non-cancerous cell growth, though challenges like scalability and biocompatibility remain.
18 citations
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April 2013 in “PLOS ONE” This study found that in a mouse model, alopecia areata was associated with changes in heart structure, biochemistry, and gene expression linked to cardiac hypertrophy after ACTH exposure.
12 citations
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August 2022 in “Biochemical Journal” This review discusses the mechanisms of skin-associated cell death and their potential role in treating inflammatory skin diseases, but presents no new clinical findings.