research Optothermal response and Tissue Damage analysis during Laser Hair Removal
This study found that laser hair removal is optimal for light to moderate skin tones using 10-15 J/cm² at 755 nm and for dark skin with 4.5-10 J/cm² at 755-1064 nm.
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30 / 1000+ resultsresearch Author response: Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation-induced tissue damage
This study found that the loss of papillary fibroblasts in the skin due to UV radiation is mainly caused by an uncontrolled inflammatory response, with T cells helping fibroblast survival.
research The Effects of Multiple Power Densities of Carbon Dioxide Laser on Photothermal Damage in Rat Skin Tissue
In this animal study, researchers found that exposure to a CO2 laser at various power levels caused significant skin damage in rats, including severe burns, coagulation, and tissue obliteration, with higher laser doses resulting in more pronounced injuries.
research Cell and Tissue Damage after Skin Exposure to Ionizing Radiation: Short- and Long-Term Effects after a Single and Fractional Doses
This study found that single high-dose irradiation in mice induced more severe acute skin injury and hair depigmentation, while fractional doses led to longer-term damage in the dermis and subcutis.
research Mdm2-p53 Signaling in Tissue Homeostasis and the DNA Damage Response: A Dissertation
This study found that Mdm2 is critical for limiting p53 activity to maintain normal stem cell function in mouse skin, with impacts on tissue homeostasis and aging.
research dsRNA Released by Tissue Damage Activates TLR3 to Drive Skin Regeneration
The researchers reported that dsRNA from damaged skin activates TLR3, promoting hair follicle regeneration, while TLR3-deficient animals fail to initiate this process, suggesting potential therapeutic approaches for hair neogenesis.
research Testing Chemotherapeutic Agents in the Feather Follicle Identifies a Selective Blockade of Cell Proliferation and a Key Role for Sonic Hedgehog Signaling in Chemotherapy-Induced Tissue Damage
This study found that certain chemotherapeutic agents, such as cyclophosphamide, disrupt feather formation and induce hair loss in mice by inhibiting cell proliferation through sonic hedgehog gene downregulation.
research Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation induced tissue damage
This study found that fibroblast loss in the upper dermis from UVR exposure is linked to a deregulated inflammatory response, with T cells playing a protective role in fibroblast survival.
research Towards a “free radical theory of graying”: melanocyte apoptosis in the aging human hair follicle is an indicator of oxidative stress induced tissue damage
This study found that oxidative stress in hair follicle melanocytes contributes to premature aging and apoptosis, providing insights into graying as a model for studying aging and testing antiaging therapies.
research Differential transcriptome study on the damage of testicular tissues caused by chronic infection of T. gondii in mice
This study provides insights into how chronic T. gondii infection might affect testicular tissue and suggests a potential impact on male fertility.
research Editor's evaluation: Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation-induced tissue damage
This study found that UV radiation-induced fibroblast depletion in the skin is primarily due to a deregulated inflammatory response, with T cells aiding fibroblast survival under stress.
research Decision letter: Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation-induced tissue damage
This study found that chronic UVR exposure in mice and humans leads to a permanent loss of papillary fibroblasts in the upper dermis, which is associated with changes in the extracellular matrix.
research Effects of Heavy Ions on Rabbit Tissues: Damage to the Forebrain
In this study, irradiation with different ionizing particles in rabbit forebrains showed that higher LET values accelerated early expression and late deterioration of forebrain damage.
research 51826 PRO-C22 - A Novel Serological Biomarker of Tissue Damage is Associated with Disease Severity, Disease Activity, and Systemic Inflammation in Patients with Hidradenitis Suppurativa
PRO-C22 can help diagnose and monitor the severity of hidradenitis suppurativa.
research The Multifaceted Functions of TRPV4 and Calcium Oscillations in Tissue Repair
This review article addresses how the TRPV4 ion channel helps cells respond to mechanical and environmental stimuli, discussing its role in calcium signaling crucial for tissue repair and fibrosis across various organ systems, and highlighting potential therapeutic targets from animal and disease models.
research Removing all obstacles: A critical role for p53 in promoting tissue renewal
This review discusses how the p53 tumor suppressor gene helps maintain adult tissue homeostasis by promoting the removal of DNA-damaged cells, with implications for treating age-related diseases and p53-deficient cancers; it reports no new results.
research Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53
This study found that combined loss of Atr and p53 in adult mice led to severe tissue degeneration and delayed regeneration due to the accumulation of highly damaged cells.
research Irradiation-induced hair graying in mice: an experimental model to evaluate the effectiveness of interventions targeting oxidative stress, DNA damage prevention, and cellular senescence
This review explores how radiation-induced hair graying can be used as a model to study the mechanisms behind hair graying, focusing on cellular senescence and potential therapeutic targets to address age-related changes. Results are not provided.
research Adipose tissue protects against skin photodamage through CD151- and AdipoQ- EVs
This study found that subcutaneous adipose tissue-derived extracellular vesicles (AT-EVs) protect skin from photodamage by enhancing fibroblast proliferation and reducing oxidative stress compared to those from adipose-derived stem cells.
research 559 Induction of tissue-specific premature stem cell aging promotes senescence-like phenotypes in remote multiple organs
This study found that dysregulation of the DNA damage response in stem cells is a common factor of aging, affecting tissues like the skin, brain, kidneys, and intestine.
research Minoxidil suppressed cerebral ischemic injury by direct effect on neural tissues but not by reducing blood pressure.
This study suggested that minoxidil's neuroprotective effect in mice was independent of its blood pressure-lowering action, unlike the effects observed with losartan and doxazosin.
research Lamins in development, tissue maintenance and stress
This review discusses the role of lamins in development, tissue maintenance, and stress response, and does not report new experimental findings.
research INTRODUCING ANTIOXIDANTS AS ESSENTIAL FOR THE MAINTENANCE OF TISSUE LIFE AS DEMONSTRATED IN HUMAN HAIR FOLLICLES
This study presents a novel optical microscopy technique showing that biomagnetic fields in hair follicles can interact with those in blood, affecting magnetic profiles until catalase breakdown.
research Introducing Antioxidants As Essential For The Maintenance Of Tissue Life As Demonstrated In Human Hair Follicles
This study found that when human hair follicles are immersed in hydrogen peroxide, the resulting oxygen bubbles indicate catalase activity, and their absence may suggest tissue death.
research Umbilical Cord Mesenchymal Stromal Cell-Derived Exosomes Rescue the Loss of Outer Hair Cells and Repair Cochlear Damage in Cisplatin-Injected Mice
In this study, UCMSC exosomes showed protective effects against cisplatin-induced hearing loss in mice by improving hearing and promoting cochlear tissue repair.
research Severe Zinc Deficiency in Male and Female Rats
This study found that severe zinc deficiency induced in weanling rats led to growth retardation, hair issues, and dermal lesions, all of which were completely reversed by zinc supplementation.
research Stress exposure modulates peptidergic innervation and degranulates mast cells in murine skin
This study found that stress increases the number of peptidergic nerve fibers and mast cell activity in mouse skin, suggesting a significant neuro-immune interaction under stress.
research Tyrosine Kinases in Autoimmune and Inflammatory Skin Diseases
This review discusses the role of tyrosine kinase signaling pathways in autoimmune and inflammatory skin diseases and reports no new clinical results, highlighting ongoing research into small-molecule tyrosine kinase inhibitors as potential treatments.
research Hair-Thread Tourniquet Syndrome: A Case Report and Literature Review
This article discusses Hair-thread Tourniquet Syndrome in children, emphasizing the need for prompt examination and intervention to prevent severe complications, but reports no new clinical results.
research ELECTROLYSIS VERSUS HIGH FREQUENCY CURRENTS IN THE TREATMENT OF HYPERTRICHOSIS
This article reviews historical approaches to electrolysis for permanent hair removal and suggests improvements in equipment, but reports no new clinical results.