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PEGylated liposomal doxorubicin improves cancer treatment effectiveness and reduces side effects like heart damage and hair loss.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

Keratin proteins are crucial for hair structure and strength.

A zinc-deficient diet stunted growth and affected organs in mice, with C57BL/6J mice showing more severe symptoms.

Alopecia patients have higher heart disease risk; statins and finasteride may help.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Hair follicle biology advancements may lead to better hair growth disorder treatments.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Some medicinal plants can help heal wounds and may lead to new treatments.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Bioprinting could improve wound healing but needs more development to match real skin.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.

New treatments targeting specific genes show promise for treating keratin disorders.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.

Researchers found 15 new genetic links to skin traits in Japanese women.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.