7 citations
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June 2015 in “The anatomical record” This study in Hexi cashmere goats found that secondary follicle activity increases with time, and Hoxc13 expression varies significantly across different growth stages, suggesting a role in follicle activity.
6 citations
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May 2022 in “Frontiers in physiology” This study suggests that an in ovo injection of CHIR-99021 promoted feather growth and follicle development in goose embryos by activating the Wnt signaling pathway.
4 citations
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February 2022 in “Frontiers in molecular biosciences” This study revealed that chronic restraint stress in mice led to significant alterations in metabolic pathways and gene expression associated with hair growth inhibition, using metabolomics and transcriptomics analyses.
4 citations
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March 2021 in “Journal of Histotechnology” In this study, researchers observed that hidradenitis suppurativa lesions were associated with reduced collagen and elastin, and increased neovascularization in areas with chronic inflammation.
3 citations
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December 2017 in “Clinical and Experimental Dermatology” In this case study, researchers observed reversible scalp hair loss associated with centrifugal lipodystrophy, potentially linked to altered leptin expression in inflamed adipose tissue.
2 citations
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November 2022 in “Journal of Biochemistry and Molecular Biology” This review discusses how aging affects hair follicle stem cells and their environment, contributing to hair loss, and explores strategies to promote hair regrowth, but reports no new results.
1 citations
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October 2025 in “International Journal of Morphology” This study found that virgin coconut oil improved skin inflammation and symptoms of seborrheic dermatitis in rats, particularly at a dose of 10 mg/kg, by reversing alterations in antioxidant and inflammatory markers.
May 2026 in “Dermatologic Surgery” This study reports conflicting evidence on whether GLP-1 receptor agonists are associated with various forms of alopecia, suggesting dermatology practitioners should consider monitoring and counseling patients using these medications.
July 2025 in “Journal of Investigative Dermatology” Androgens reduce THY1 in skin cells, leading to less fat, more fibrosis, and worse healing in males.
December 2024 in “Microorganisms” This study analyzed changes in the microbiota during antler velvet regeneration in sika deer and found significant differences in microbial community composition between 15 and 30 days post-pedicle casting, highlighting the potential roles of specific bacteria in wound healing and tissue regeneration.
January 2024 in “Archives of pathology & laboratory medicine” This study observed that adipose tissue infiltration and ESGC displacement in scalp biopsies were more frequently found in frontal fibrosing alopecia and may play a role in the development of scarring alopecia.
August 2023 in “International Journal of Molecular Sciences” This review discusses the use of human-to-mouse xenografting to study human skin processes in vivo, highlighting its importance for understanding skin regeneration and pathology while identifying knowledge gaps and challenges in applying these findings to human skin.
June 2023 in “Skin Research and Technology” In this study, researchers used high-resolution MRI to distinguish anatomical differences in the scalp and hair follicles between tertiary androgenetic alopecia and severe alopecia areata, identifying subcutaneous tissue layer thickness as a key discriminative factor with high diagnostic value.
February 2023 in “Research Square (Research Square)” This study found that testosterone contributed to increased arterial stiffness and cardiovascular damage in female mice, linked with decreased estrogen receptor expression, and suggests implications for women with polycystic ovarian syndrome or those taking testosterone.
This review compiles existing information on the pathogenesis of androgenetic alopecia, highlighting its genetic, hormonal, and environmental factors, but reports no new clinical findings.
May 2020 in “Authorea (Authorea)” This review discusses the diverse functions and therapeutic potential of ectopic olfactory receptors throughout the body, emphasizing their roles in various cellular processes and potential in cancer detection and therapy, but reports no new clinical results.
October 2019 in “Skin appendage disorders” This study revisits and reproduces Felix Pinkus' concept of the vitreous membrane in hair follicles, suggesting these structures may play a role in differentiation or nutrition due to their location in metabolically dynamic regions.
January 2019 in “The Review of Laser Engineering” This study observed that multiphoton excitation microscopy revealed changes in vascular structure and hair papillae in mice subcutaneous tissue following cyclophosphamide treatment for chemotherapy-induced alopecia.
April 2017 in “The Journal of urology/The journal of urology” This study found that Sonic Hedgehog protein treatment enhanced the sprouting and regeneration of pelvic ganglia and cavernous nerves after injury, with localization of delivery affecting outcomes.
January 2017 in “Open Journal of Endocrine and Metabolic Diseases” This case report identifies an adolescent with symptoms indicative of Dunnigan-type partial lipodystrophy, emphasizing the need for early diagnosis to manage associated metabolic complications and improve self-esteem.
May 2004 in “Archives of Facial Plastic Surgery” This book review in the Archives of Facial Plastic Surgery discusses "Comprehensive Facial Rejuvenation: A Practical and Systematic Guide to Surgical Management of the Aging Face" but does not provide new clinical research results.
16 citations
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October 1979 in “The Journal of Dermatologic Surgery and Oncology” In this report, a 17-year-old boy received successful scalp reduction surgery for alopecia due to a thermal burn, achieving excellent cosmetic results without hypertrophic or keloidal scarring.
4 citations
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August 2022 in “International Journal of Molecular Sciences” This study found that cultured foreskin is not suitable for studying H2A.J-related tissue changes during radiation-induced dermatitis due to existing high H2A.J expression and cytokine secretion even without irradiation.
August 2024 in “Nihon Ika Daigaku Igakkai Zasshi” In this study, researchers used tissue clearing techniques on human skin and scar tissue for the first time to render them optically transparent, with the aim of revealing atypical structures and improving protocols for observing scar tissue changes.
60 citations
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November 2023 in “Biology” This review explores the role of aging-related changes in skin, discussing how impaired skin barrier function may contribute to systemic inflammation, or "inflamm-aging," which in turn could impact the broader decline in organ and tissue function seen in aged individuals.
37 citations
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December 2003 in “Reproductive Toxicology” The researchers reported that the rat Hershberger assay reliably detected endocrine-disrupting effects of finasteride, procymidone, and 17α-methyltestosterone, validating the assay's sensitivity for identifying hormonal activity.
20 citations
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January 2005 in “Australasian Journal of Dermatology” This article describes a case of late-onset focal dermal elastosis in a 73-year-old woman, characterized by flat pale yellow lesions and increased normal elastic fibers, distinct from pseudoxanthoma elasticum.
1 citations
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November 2021 in “American Journal of Clinical Pathology” In this study, autopsies of children who suffered fatal abuse revealed stress-associated markers like telogen effluvium and thymus involution, which may help pathologists identify chronic abuse cases.
December 2025 in “Russian Journal of Skin and Venereal Diseases” This study found that in patients with non-cicatricial alopecia, hair follicles and their sheaths were thinner compared to controls, especially in cases of alopecia areata and telogen effluvium, with notable thinning beginning in the subcutaneous fat tissue.
April 2016 in “Journal of Investigative Dermatology” This study found that Pdgfα signaling is crucial for maintaining dermal adipose tissue in mice by initiating dermal adipocyte stem cell proliferation, with implications for age-related skin defects.