2 citations
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June 2023 in “Journal of cell science” In this study, researchers found that specific mutations in iRhom2 in mice lead to skin and hair abnormalities which depend on the presence of the protein ADAM17, suggesting a complex role for iRhom2 in tissue development and potential implications for treating tylosis with oesophageal cancer.
16 citations
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April 2022 in “PLoS ONE” This study identified a set of tumour-suppressive microRNAs (miRNAs), termed 'normomiRs', that are highly expressed in normal tissues but low in tumors, with miR-206 and miR-381 showing significant in vitro cancer inhibition, highlighting their potential for miRNA-replacement therapies across multiple cancer types.
5 citations
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January 2012 in “PubMed” This study observed that anti-multiple nuclear dots antibodies, typically markers for primary biliary cirrhosis, were also present in patients with various autoimmune and connective tissue diseases, without correlating to disease activity or specific skin features.
1 citations
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January 2024 in “Advances in Engineering Technology Research” This study found that bone marrow mesenchymal stem cells from Guizhou miniature pigs showed stable growth and multidirectional differentiation potential, making them ideal for tissue engineering applications.
August 2025 in “Animal Bioscience” In this study, researchers examined the methylation patterns in the skin tissues of Alpine Merino sheep with varying wool fiber diameters, finding that specific methylated RNAs linked to the Wnt, Notch, and TGF-ẞ signaling pathways may influence fiber diameter and potentially improve wool quality.
72 citations
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May 1993 in “The Journal of Cell Biology” This study detailed the structure and amino acid composition of sheep trichohyalin, noting its presence in various tissues and suggesting a possible functional role beyond structural support in hair follicles.
January 2005 in “mediaTUM – the media and publications repository of the Technical University Munich (Technical University Munich)” This study found that vitamin D regulation plays a crucial role in connecting metabolic and cardiovascular conditions, influencing gene expression related to these disorders in both kidney and heart tissues.
January 2026 in “Biomedicines” This study identified increased expression of ACAA1 and its regulation by hsa-miR-1343-3p, linking androgenetic alopecia to lipid metabolism pathways, particularly through PPAR signaling, in scalp tissues.
6 citations
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August 2008 in “Journal of Forensic Sciences” This study used electron microscopy to characterize tissues on telogen hair roots, finding that tissue quality, including nucleated and nonnucleated epithelial cells, may play a crucial role in DNA typing for forensic analysis.
8 citations
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October 2006 in “Current Pharmaceutical Design” This review discusses current genomics and proteomics research on cutaneous autoimmune diseases, noting overlapping gene patterns but highlighting the scarcity of data on local gene expression in affected tissues.
33 citations
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February 2009 in “European journal of pharmaceutics and biopharmaceutics” This study found that porcine ear skin is more suitable than excised human skin for investigating the efficacy of barrier emulsions in preventing pollen allergen penetration due to its lack of tissue contraction.
28 citations
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November 2009 in “Journal of Structural Biology” This study found that the molecular structure of hair is more sensitive to synchrotron X-ray radiation than its supramolecular architecture, indicating potential concerns for biological analyses using such radiation.
7 citations
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January 2016 in “Methods in molecular biology” This study describes the process of isolating and analyzing multipotent stem cells from mouse hair follicles for potential use in tissue engineering and regenerative medicine.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that Imaging Mass Cytometry effectively visualizes multiple biomarkers in alopecia areata, enhancing analysis of immune cell and tissue interactions in hair pathology.
This study found that mild skin injuries in rats, especially those dosed with dihydrotachysterol, lead to mineral deposits in hair follicle tissue within 6-12 hours, as confirmed by chemical and X-ray diffraction analyses.
5 citations
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January 2025 in “Burns & Trauma” This review highlights recent research using single-cell RNA sequencing and machine learning in wound healing, revealing significant insights into fibroblast diversity, immune cell dynamics, and the spatial organization of cells, which may transform therapeutic strategies for chronic wounds, fibrosis, and tissue regeneration.
2 citations
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January 2023 in “Cancers” This study observed that COVID-19 infection in cancer patients may worsen lung damage, leading to over a 50% reduction in lung volume and increased lung density due to scar tissue formation.
September 2025 in “Bioscientia Medicina Journal of Biomedicine and Translational Research” In this study, PRP-derived exosomes significantly outperformed minoxidil in promoting hair regeneration in a murine model of androgenetic alopecia, with the combination of both treatments showing enhanced follicular regeneration and increased markers of tissue proliferation and Wnt signaling pathway activity.
December 2022 in “Research Square (Research Square)” In this study, type I interferon response-related genes activated by RIG-1 and IL-17 signaling pathways were significantly up-regulated in both hair follicles and skin tissues affected by chronic discoidal lupus erythematosus.
21 citations
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August 2020 in “Stem Cell Research & Therapy” This meta-analysis suggests that stem cell therapy may reduce burn wound area and improve healing-related factors in preclinical models, indicating potential for future clinical studies on burn treatment.
September 2018 in “Gynecology & Obstetrics” In a meta-analysis of 210 hair tourniquet syndrome cases, this study reported that 44.2% involved the penis, 40.4% the toes, and 8.6% fingers, highlighting the condition's potential severity and underreporting, especially in infants and some adults with cognitive impairments.
November 2025 in “Journal of Investigative Dermatology” Certain immune cells in atopic dermatitis skin could be targeted for treatment.
January 2025 in “Advances in Dermatology and Allergology” This literature review conducted a comprehensive analysis of existing studies on micro-needling mesotherapy in dermatology and aims to offer a practical guide for its clinical application, though it provides no new experimental findings.
In this retrospective analysis, researchers evaluated 54 patients undergoing soft tissue reconstruction for scalp and forehead defects and reported excellent aesthetic outcomes with local flaps for defects up to 50 cm², while larger defects typically required additional skin grafting.
53 citations
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June 2012 in “Annales d'Endocrinologie” This review discusses the range and causes of adipose tissue diseases, emphasizing genetic and acquired forms of lipodystrophy, but it reports no new clinical results.
14 citations
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June 2022 in “BMC genomics” This study identified key genes involved in hair follicle development in Merino sheep, offering insights for improving wool production and providing a basis for future breeding programs.
research Hair
3 citations
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January 2014 in “Elsevier eBooks” This article reviews the use of hair analysis in forensic and environmental toxicology for detecting potentially toxic elements and drugs, but it reports no new research findings.
1 citations
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August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study explores ear pinna development in mice and reports that elastic cartilage formation is disrupted in a short ear mutant, correlating with increased adult adipocytes and impaired chondrogenesis.
1 citations
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February 2021 in “Journal of Cosmetic Dermatology” In this study, mathematical analysis suggested that a 30°-sapphire blade caused the least tissue injury during hair restoration, while a rectangular blade caused the most.
March 2023 in “JAAD case reports” This article reviews the genetic foundations of keratins in maintaining epithelial tissue integrity and links specific keratin variants to diverse ichthyosis forms, without presenting new clinical findings.