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Uncombable hair syndrome causes frizzy hair and can affect the nervous system, eyes, and ears, often co-occurring with other hair, skin, nail, and teeth conditions, and is linked to three specific gene mutations.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Reconstruct lips with proper planning, templates, and revisions for appearance and function.

Using cheek skin and cartilage grafts for nose reconstruction after skin cancer surgery can maintain shape and function but may require multiple surgeries and hair removal in men.

Burn reconstruction improves with new techniques, materials, and tissue engineering.

A new hair transplant method creates one appealing scar, uses donor hair better, and speeds up surgery.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Botox increased hair count in men with baldness and might work by improving scalp blood flow.

Accurate diagnosis is key for treating different kinds of hair loss, and immune response variations may affect the condition and treatment results.

Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.

ILK is essential for skin development, pigmentation, and healing.

Polypoid cystitis can mimic bladder cancer but can be effectively treated with surgery, stents, and medication.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.

Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.

Wnt signaling is crucial for skin wound healing and reducing scars.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Keratins are important for skin cell health and their problems can cause diseases.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Improved dermabrasion techniques in 1987 led to better treatment results for skin issues like acne scars.

Detailed patient history and physical exams are crucial for diagnosing hair loss.

Over 67 genes linked to ichthyosis help improve diagnosis and treatment.

Non-invasive methods show promise for diagnosing skin diseases like psoriasis and lupus but need more research for regular use.