25 citations
,
March 2000 in “Journal of Endocrinological Investigation” Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.
24 citations
,
October 2022 in “Revista Brasileira de Farmacognosia” This review discusses the pharmacological actions of mangiferin and the potential of delivery carriers to overcome its limitations, but reports no new clinical results.
24 citations
,
October 2016 in “Oncotarget” This study found that finasteride was associated with more reproductive adverse effects, including sexual dysfunction in men and fetal harm in women, compared to minoxidil in reported alopecia cases.
24 citations
,
July 2015 in “Biogeosciences” This study found that the growth of hair ice on dead wood requires the biological activity of a winter-active fungus, specifically Exidiopsis effusa, which shapes and stabilizes the ice structures.
24 citations
,
March 2002 in “Expert opinion on investigational drugs” This review discusses various anti-androgen treatments for hirsutism, including androgen receptor blockers and inhibitors, and emphasizes the role of diagnosis in selecting the most appropriate therapy, but reports no new clinical results.
23 citations
,
September 2016 in “BMC musculoskeletal disorders” This study suggests that methotrexate use among rheumatoid arthritis patients is associated with patient-reported side effects and tolerability issues that may not be fully recognized by physicians.
22 citations
,
July 2017 in “BMC complementary and alternative medicine” This study documented the use of 41 plant species in the West Bank for treating hair and scalp disorders, highlighting their folkloric significance and potential for new cosmetic and cosmeceutical products.
22 citations
,
November 2011 in “Journal of Analytical Toxicology” This review discusses the relevance of human androgen receptor action in sports doping and examines the potential of cell-based biological assays for detecting androgenic anabolic steroid use, without presenting new research findings.
22 citations
,
May 2011 in “American Journal of Clinical Dermatology” This review discusses psychocutaneous disorders in children with an emphasis on primary psychiatric disorders manifesting through skin symptoms, but provides no new clinical findings.
21 citations
,
March 2019 in “Critical Reviews in Clinical Laboratory Sciences” This review discusses the role of the androgen receptor in breast cancer diagnosis and treatment, and notes a lack of new research results on its therapeutic potential.
21 citations
,
April 2015 in “Psychology Research and Behavior Management” This review evaluates various cognitive-behavioral interventions for trichotillomania but does not report new clinical findings, highlighting the need for further research on their efficacy.
21 citations
,
March 2013 in “Cancer Epidemiology, Biomarkers & Prevention” This study found that early-onset baldness in African-American men is associated with an increased risk of developing prostate cancer and more aggressive tumors, with potential interactions involving age and smoking.
21 citations
,
December 2007 in “Primary Care” This article reviews the challenges in treating PCOS, noting the potential benefits of insulin sensitizers on ovulatory function and pregnancy outcomes, and calls for more long-term studies on metabolic interventions.
20 citations
,
November 2013 in “The Open Cancer Journal” This observational study provides cause-specific mortality estimates to help patients and physicians better understand long-term outcomes for localized prostate cancer based on initial treatment choices.
20 citations
,
April 1999 in “British journal of plastic surgery” This study found that using a ruby laser for hair removal resulted in a significant average reduction of 56.4% in hair density among participants dissatisfied with other methods.
19 citations
,
May 2019 in “JAMA dermatology” This study found that patients with alopecia areata had an increased risk of mortality from self-harm, psychiatric diseases, and lung cancer compared to the general population.
19 citations
,
December 2016 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics” This study found that multiple ion channel modulators, used here at clinical concentrations, increased intracellular calcium release in prostate and breast cancer cell lines.
19 citations
,
January 2012 in “Dermato-endocrinology” This study suggests that moderate elevated prolactin levels are unlikely to cause significant hair loss in women, but still warrant further diagnostic investigation to rule out a prolactin-producing pituitary tumor.
19 citations
,
March 1988 in “International Journal of Dermatology” This paper reviews different types of hair shaft dysplasias and does not report any new clinical findings.
18 citations
,
October 2020 in “PLoS ONE” This study highlights the interconnected emotional distress between patients with end-stage COPD and their family caregivers, emphasizing that both parties' functional and emotional variables influence each other's distress.
18 citations
,
May 2016 in “Aesthetic Surgery Journal” This study found that body hair transplantation using follicular unit extraction was effective and resulted in high satisfaction among selected patients with limited scalp donor hair.
18 citations
,
March 2015 in “Journal of Endocrinological Investigation” This study found that ZP4 expression was highest among PCOS patients with regular menstrual cycles, which may be linked to mature follicle presence, but no correlation with clinical indices was observed.
18 citations
,
July 2010 in “Expert Review of Endocrinology & Metabolism” This study identified an association between the FTO gene and susceptibility to PCOS, providing the first genetic evidence linking PCOS to obesity.
18 citations
,
September 2006 in “Dermatologic Surgery” This study reported that squamous cell carcinomas of the scalp can become extraordinarily aggressive, highlighting the need for early diagnosis and careful use of treatment strategies like wide excision and radiation therapy.
17 citations
,
May 2023 in “Aesthetic Plastic Surgery” This review found that among emerging technologies for skin anti-aging, stem cell therapies using recipient chimerism might be more beneficial than CRISPR-Cas9 and other current innovations, though further studies on safety and efficacy are needed.
17 citations
,
September 2020 in “Journal of Endocrinological Investigation” This study found that the gut microbiota composition in patients with post-finasteride syndrome differs significantly from healthy controls, with reduced diversity and specific microbial changes, suggesting a potential diagnostic marker and therapeutic target.
17 citations
,
January 2016 in “American Journal of Epidemiology” This study suggests that any baldness, particularly moderate balding, is associated with a higher risk of fatal prostate cancer in men, supporting a possible link between hair loss and prostate cancer mechanisms.
17 citations
,
August 2015 in “Expert Opinion on Pharmacotherapy” This article discusses the social and psychological impact of hair disorders and the challenges in their treatment, but reports no new clinical results.
17 citations
,
November 2012 in “Maturitas” This review discusses the management of hair loss in midlife women, focusing on female pattern hair loss, hair shaft alterations from hair care, and telogen effluvium, and reports no new research findings.
17 citations
,
April 2007 in “Kidney international” This study found that 1,25 dihydroxyvitamin D3 significantly increased the expression and activity of vasculoprotective natriuretic peptide receptor-A in cultured inner medullary collecting duct cells, suggesting a potential mechanistic role in cardiovascular and renal benefits.