March 2022 in “IntechOpen eBooks” Botulinum Neurotoxin-A can treat acne, oily skin, rosacea, hair loss, prevent scars, relieve nerve pain, reduce excessive sweating, and manage psoriasis, but more trials are needed to confirm its effectiveness.
April 2021 in “International journal of advanced ayurveda, yoga, unani, siddha and homeopathy” Homeopathy can effectively treat hair loss and promote regrowth.
January 2021 in “American journal of dermatological research and reviews” The muscle damage was caused by T-cell large granular lymphocytic leukemia, not dermatomyositis.
January 2019 in “Deleted Journal” Biofield Energy Healing may promote hair growth and treat skin disorders by enhancing hair follicle development.
January 2018 in “Clinical approaches and procedures in cosmetic dermatology” Low-Level Laser Therapy might be an effective alternative hair loss treatment for some people.
January 2017 in “Clinical approaches and procedures in cosmetic dermatology” Low-Level Laser Therapy might be a good alternative for hair loss when other treatments fail, but its effectiveness varies and more research is needed.
January 2017 in “Springer eBooks” Understanding genes and hormones is crucial for managing male puberty and sex development disorders.
January 2008 in “American journal of clinical dermatology” December 2022 in “Regenerative Therapy” November 2022 in “International Journal of Applied Pharmaceutics” Ergostadienol from Moringa seed oil may help prevent hair loss.
The review highlights the potential of natural products in treating hair loss by activating the Wnt/β-catenin signaling pathway, which is crucial for hair follicle development, hair cycle regulation, and hair regeneration. Traditional treatments like finasteride and minoxidil have limitations, prompting research into natural compounds such as polyphenols, which show promise in promoting hair growth with fewer side effects. Key natural products identified include extracts from Aconitie Ciliare Tuber, Centipeda minima, Ginkgo biloba, Malva verticillata, and Prunus mira, which enhance β-catenin activity and other growth factors in dermal papilla cells. These findings suggest that natural products could offer safer and effective alternatives for hair loss treatment, with future research needed to explore clinical applications and potential combinations with existing drugs.
506 citations,
March 2005 in “The Journal of Clinical Endocrinology and Metabolism” Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.
14 citations,
June 2017 in “Immunity” Special immune cells called Treg cells are important for maintaining and regenerating hair by activating a specific growth signal in hair stem cells.
209 citations,
March 1989 in “Journal of The American Academy of Dermatology” Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.
192 citations,
April 2017 in “Cell host & microbe” Hair follicle development and microbes help regulatory T cells gather in newborn skin.
13 citations,
February 2015 in “Journal of Pharmaceutical Sciences” Three finasteride forms exist; "form X" doesn't.
18 citations,
March 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
255 citations,
October 1985 in “The Journal of Clinical Endocrinology & Metabolism” Spironolactone treatment increases the amount of testosterone available in the body.
12 citations,
March 2016 in “BBA clinical” Increased Toll-like receptors in blood cells may contribute to alopecia areata and could be a target for new treatments.
April 2024 in “International journal of molecular sciences” Alopecia areata and vitiligo share immune system dysfunction but differ in specific immune responses and affected areas.
16 citations,
April 2014 in “Expert Opinion on Pharmacotherapy” Teriflunomide is an effective and safe first-line oral treatment for relapsing multiple sclerosis.
11 citations,
February 2011 in “The Journal of Urology” Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.
September 2023 in “Biology of reproduction” New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.
106 citations,
December 2016 in “Cell Stem Cell” PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.
68 citations,
February 1996 in “Obesity Surgery” Taking zinc sulphate stopped and reversed hair loss in patients after weight loss surgery.
5 citations,
January 2021 in “iScience” Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.
February 2024 in “Agroèkoinfo” Environmental factors and grain products affect hair loss, with low cobalt in hair possibly predicting the condition.
November 2022 in “CARDIOMETRY” A group has developed therapies that show promise for treating cancer and various other conditions.
June 2004 in “Bulletin of Pharmaceutical Sciences. Assiut University” The natural hair treatment with Cantharidin works best for hair loss.
195 citations,
July 2005 in “American Journal of Human Genetics” Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.