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A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

LGBT individuals have unique skin health needs, including higher STD risks and side effects from gender-affirming treatments, requiring dermatologists to offer knowledgeable and culturally competent care.

Hormones might affect the skin condition hidradenitis suppurativa, but their exact role is unclear.

Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

Young women with diffuse hair loss may have low SHBG levels, which could lead to more active testosterone and contribute to their hair loss.

The document concludes that treatment for cutaneous T-cell lymphoma should be customized to each patient's disease stage, balancing benefits and side effects, with no cure but many patients living long lives.

Hormones, nutrition, and seasonal changes regulate hair growth cycles, with androgens extending growth phases and factors like aging and malnutrition affecting hair loss and thinning.

Alopecia is linked to various health and mental conditions, impacts life quality, and needs medical attention beyond its cosmetic effects.

People with pemphigus are more likely to have conditions like hypothyroidism, inflammatory bowel disease, and diabetes.

Certain microRNAs are more common in balding areas and might be involved in male pattern baldness.

The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.

Children with trichotillomania often pull hair from their scalp, and parents may not notice; stress can trigger it, and asking detailed questions helps in diagnosis and treatment.

A man with severe hair loss saw hair and nail improvement after 10 months on tofacitinib without side effects.

The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.

Mutations in certain receptors can cause diseases and offer new treatment options.

Different hormones affect hair growth and conditions, with some causing hair loss and others promoting it.

Systemic diseases can cause hair loss, which is often reversible with treatment.

Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.

Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

Scientists have made progress in growing mini-organs and regenerating parts of the skin, with plans to treat hair loss in a future trial.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

Systemic retinoids are effective for psoriasis but have side effects; benefits may outweigh risks, especially when reducing cancer risks from other treatments.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

The document concludes that diagnosing PCOS in teenagers is difficult and should focus on specific hormone levels and menstrual irregularities, while also considering treatment for symptoms and related health issues.

Hormonal changes during and after pregnancy can cause hair growth changes and hair loss, with treatments available for some conditions.

Primary care for PCOS focuses on lifestyle changes, medication based on symptoms, and mental health, with diabetes screening and specialist referral for severe cases.

CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.