This study found a significant association between higher serum anti-thyroperoxidase (anti-TPO) antibody levels and the occurrence of chronic spontaneous urticaria, suggesting that testing for anti-TPO antibodies alongside primary thyroid markers might be important in managing this condition.
2 citations
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December 2015 in “Journal of dermatology research and therapy” This study compared serum zinc, vitamin B12, folic acid levels, iron metabolism, and thyroid function between chronic telogen effluvium patients and healthy controls, but it reports no specific clinical results.
November 2023 in “International Journal of Trichology” This study, conducted at a tertiary care hospital, found no statistically significant association between male pattern hair loss and levels of serum ferritin or thyroid-stimulating hormone, suggesting these factors may not play a role in this condition.
April 2011 in “Medical Journal of Tabriz University of Medical Sciences and Health Services” This study found that patients with alopecia areata may have higher rates of autoimmune disorders, particularly thyroid dysfunction, compared to the general population.
July 2025 in “International Journal of Pharmacology and Clinical Research” This study surveyed individuals and found that awareness and understanding of thyroid disorders, particularly symptom recognition and the importance of early detection, are low, highlighting the need for targeted public health initiatives to improve knowledge and management.
4 citations
,
January 2025 in “JAAD reviews.” This literature review found that pediatric patients with vitiligo may have increased risks of conditions such as atopic dermatitis, alopecia areata, autoimmune thyroid disease, and psychiatric disorders, impacting their quality of life. Screening should consider these risks for effective management.
October 2025 in “Diseases” This study reports that women with hair loss had significantly lower levels of several biomarkers, including hemoglobin, iron, copper, selenium, vitamin D, vitamin B12, folate, and thyroid hormones, compared to healthy controls.
22 citations
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January 2017 in “Acta Endocrinologica” A woman with multiple autoimmune diseases showed improvement in hair loss but not in skin discoloration after treatment.
April 2020 in “IP Indian journal of clinical and experimental dermatology” This study explores autoimmune associations in pediatric patients with alopecia areata at a tertiary care center but reports no new clinical findings.
92 citations
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January 2013 in “Dermatology” This study reports a high prevalence of comorbid autoimmune conditions, particularly thyroid disorders and psoriasis, among vitiligo patients in Boston teaching hospitals.
38 citations
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October 2006 in “Fertility and Sterility” The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.
34 citations
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March 2015 in “Clinical and Experimental Dermatology” This study observed that patients with pemphigus have a higher incidence of hypothyroidism, inflammatory bowel disease, and diabetes compared to the general population.
9 citations
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January 2007 in “Gynecological Endocrinology” This case report presents the first known instance of combined polycystic ovary syndrome and autoimmune polyglandular syndrome type 2 in a patient, exploring potential mechanisms for their interrelation.
4 citations
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February 2025 in “Journal of Autoimmunity” This systematic review and meta-analysis reports a significant familial risk of autoimmune and related conditions among relatives of individuals with Alopecia Areata, highlighting the importance of comprehensive family monitoring and genetic counseling.
1 citations
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February 2023 This study found a high prevalence of thyrotoxicosis among females in Gujranwala, Pakistan, particularly noting typical symptoms such as goiter, sweating, and menstrual irregularities.
1 citations
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September 2021 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study suggests that female patients with alopecia areata, especially those with nail abnormalities and atopic diseases, have a higher prevalence of autoimmune disease comorbidities.
In this study, researchers evaluated hirsutism in young females aged 18-24 using the modified Ferriman-Gallwey scoring system, finding that 52% showed mild to moderate-to-severe symptoms, often linked to menstrual irregularities and underlying endocrine disorders like polycystic ovary syndrome and thyroid issues.
June 2026 in “British Journal of Dermatology” This study found that individuals with frontal fibrosing alopecia have increased odds of thyroid disease, lupus erythematous, vitiligo, and heart disease, supporting the consideration of FFA as a systemic disorder.
August 2025 in “Dermatology and Therapy” This study found that among US adults with vitiligo, the most prevalent autoimmune comorbidities were thyroid disease and alopecia areata, with evidence suggesting greater vitiligo extent increases prevalence of several autoimmune conditions.
May 2025 in “JEADV Clinical Practice” This study found that laboratory testing practices for alopecia areata vary among international hair experts, with the majority routinely conducting thyroid function and complete blood count tests, yet exhibiting diverse approaches toward testing for other conditions or before prescribing systemic therapy.
March 2025 in “JEADV Clinical Practice” In this retrospective chart review, researchers found that patients with scarring alopecia, including central centrifugal cicatricial alopecia, have a higher prevalence of various systemic comorbidities, such as vitamin D deficiency and metabolic syndrome, compared to the general US population.
7 citations
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January 2012 in “International Journal of Trichology” This article highlights differences in childhood alopecia areata compared to adult cases but reports no new clinical findings.
1 citations
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July 2025 in “Middle East Fertility Society Journal” This study found that women with PCOS had significantly higher levels of several autoantibodies compared to healthy controls, suggesting a potential autoimmune component to PCOS that might aid in better disease characterization and personalized management.
1540 citations
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October 2008 in “Fertility and Sterility” This review discusses the definition of polycystic ovary syndrome proposed by the AE-PCOS Society Task Force, emphasizing hyperandrogenism, ovarian dysfunction, and excluding related disorders, while noting potential variations needing more research.
January 2016 in “Springer eBooks” This review examines the clinical presentation and management strategies for alopecia areata, focusing on pediatric patients, and highlights the need for addressing its psychological impacts; it reports no new clinical findings.
2 citations
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February 2014 in “Journal of the European Academy of Dermatology and Venereology” This letter reports three cases of diffuse hair loss linked to hyperprolactinaemia but does not present new research findings.
April 2023 in “Journal of Investigative Dermatology” This study provides an updated systematic review and meta-analysis showing that alopecia areata is associated with significantly higher odds of several autoimmune and metabolic comorbidities compared to healthy controls.
15 citations
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October 2013 in “Journal of the American Academy of Dermatology” This study found that in adults with vitiligo, certain autoimmune diseases are associated with factors like age, sex, and extent of vitiligo, suggesting tailored screening strategies based on these variables.
December 2024 in “Clinical Cosmetic and Investigational Dermatology” This study reports that vitiligo prevalence in a Saudi cohort is similar to global figures, with stress as a common trigger, frequent lesional pruritus, and widespread thyroid issues and low vitamin D levels.
12 citations
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February 2023 in “Journal of Personalized Medicine” This review discusses the complex interplay of genetic and environmental factors in Type 1 Diabetes Mellitus and its frequent association with other autoimmune conditions, focusing on personalized medicine to potentially improve patient care.