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    Glossary Thyroid Peroxidase Antibodies

    immune proteins attacking thyroid enzyme, linked to autoimmune disorders

    Thyroid Peroxidase Antibodies (TPO Antibodies) are immune system proteins that mistakenly target and attack thyroid peroxidase, an enzyme crucial for the production of thyroid hormones. Elevated levels of TPO antibodies are often associated with autoimmune thyroid disorders, such as Hashimoto's thyroiditis and Graves' disease, and can lead to symptoms like hair loss, fatigue, and weight changes.

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    1. Thyroid peroxidase Antibody (TPO Ab) Can Be Used As a Marker For Persistence of Symptoms of Hypothyroidism in Patients with Primary Hypothyroidism Despite Normal TSH Level: Cross-Sectional Study Mansoura Medical Journal · 2025
    2. Thyroid peroxidase antibodies in patients with telogen effluvium Journal of the European Academy of Dermatology and Venereology · 2010 · 12 citations
    3. Platelet-rich plasma efficacy in alopecia areata patients with normal and elevated levels of antibodies against thyroglobulin and thyroid peroxidase Folia Medica · 2024
    4. Prevalence of anti-thyroid peroxidase antibodies among women with polycystic ovary syndrome Scientific Reports · 2025 · 2 citations
    5. Thyroid antibodies in Hashimoto’s thyroiditis patients are positively associated with inflammation and multiple symptoms Scientific Reports · 2024 · 23 citations
    6. A descriptive study of alopecia patterns and their relation to thyroid dysfunction International Journal of Trichology · 2013 · 22 citations
    7. Dehydroepiandrosterone Sulfate Level is Lower in Polycystic Ovary Syndrome Patients with Autoimmune Thyroid Disease Turkiye Klinikleri Journal of Endocrinology · 2015
    8. Evaluation of Thyroid Autoimmunity in Female Patients with Telogen Effluvium Türkiye klinikleri tıp bilimleri dergisi · 2014 · 2 citations
    9. SUN-585 A Case of Atypical Myxedema in Hypothyroidism Journal of the Endocrine Society · 2019
    10. Thionamide-Responsive Alopecia Areata in a 11 Year Girl Indian Journal of Endocrinology and Metabolism · 2023
    11. Hepatitis C Treatment and Alopecia Totalis Journal of Investigative Dermatology Symposium Proceedings · 2013 · 8 citations
    12. Evaluation of several immune and inflammatory indicators and their association with alopecia areata Journal of cosmetic dermatology · 2021 · 5 citations
    13. Dystrophic-Anagen Effluvium Occurring During Pegylated Interferon-α-2a/Ribavirin Therapy Hepatitis Monthly · 2015 · 2 citations
    14. Hypothyroidism with too Many Associations Case Report Journal of Armed Forces Medical College · 2022
    15. Evaluation of the Clinical and Sociodemographic Features of Turkish Patients with Vitiligo. PubMed · 2016 · 14 citations
    16. Lupus erythematosus, thyroiditis, alopecia areata and vitiligo – A multiple autoimmune syndrome type 3 case presentation Our Dermatology Online · 2017
    17. Prevalence of thyroid dysfunction in patients with systemic lupus erythematosus: A descriptive cross sectional study Indian Journal of Rheumatology · 2020 · 1 citations
    18. Thyroid Autoimmunity in Patients with Skin Disorders InTech eBooks · 2012 · 2 citations
    19. Is hormone testing worthwhile in patients with female pattern hair loss? PubMed · 2020 · 1 citations
    20. Identification of tpo, tg, tshr and ana antibodies associated with thyroid disorders Malaysian Journal of Microbiology · 2024
    21. Organ Specificity in Autoimmune Diseases: Thyroid and Islet Autoimmunity in Alopecia Areata The Journal of Clinical Endocrinology & Metabolism · 2015 · 32 citations
    22. The prevalence of thyroid function test abnormalities and serum thyroid autoantibodies in vitiligo and alopecia areata patients in Saudi Arabian population International Journal of Research in Dermatology · 2024
    23. Adverse events of the thyroid peroxidase inhibitor methimazole in the treatment of hyperthyroidism: a comprehensive analysis from the first quarter of 2004 to the first quarter of 2025 Frontiers in Endocrinology · 2025
    24. Study on Autoimmune Thyroid Disorders in Chronic Spontaneous Urticaria at a Tertiary Care Central Rural Hospital in India Cureus · 2023
    25. Prevalence and Levels of Thyroid Autoantibodies in Polycystic Ovary Syndrome—Impact of TSH- and BMI-Matched Comparisons: A Systematic Review and Meta-Analysis International Journal of Molecular Sciences · 2025 · 3 citations
    26. Association between Alopecia Areata and Thyroid Disorders Ibrahim Cardiac Medical Journal · 2023
    27. The impact of exogenous vitamin D on thyroid autoimmunity in euthyroid men with autoimmune thyroiditis and early-onset androgenic alopecia Pharmacological Reports · 2021 · 5 citations
    28. The role of vitamin D3 deficiency in the etiopathogenesis of autoimmune thyroid diseases 2023
    29. The impact of levothyroxine on thyroid autoimmunity and hypothalamic–pituitary–thyroid axis activity in men with autoimmune hypothyroidism and early-onset androgenetic alopecia Endokrynologia Polska · 2021 · 1 citations
    30. Selenium’s Role on Thyroid Autoimmunity and Cognitive Dysfunction in Elderly European journal of geriatrics and gerontology · 2023