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Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

Hair loss in men treated best with early medication or transplant, new treatments researched.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Finasteride improves hair loss in women with hyperandrogenism.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

Certain genes control the color of human hair by affecting pigment production.

Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.

Correcting nutrient deficiencies may help with hair loss, but the benefits of supplements without a deficiency are uncertain and could be harmful.

Excessive selenium from a supplement caused toxicity but patients recovered with care.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

Some treatments, like corticosteroids and sensitizing agents, can help with alopecia areata, but more high-quality research is needed.

Iron deficiency common in women, not always linked to hair loss; more research needed.

Hair loss from Telogen Effluvium usually gets better within 6 months after addressing the cause.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

There is no clear recommendation for using selenium in cancer patients; it may be beneficial to correct low selenium levels before treatment.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.