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Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.

Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Using steroids can increase the risk of heart problems.

Mice skin has components that could help with hair growth and might be used for diabetes treatment.

Treatment can improve survival and symptoms in dogs with Cushing's disease, but outcomes are unpredictable.

Puberty often causes skin issues like acne and excessive sweating, and treatments require patience as results may vary.

Treating excessive hair in women requires a holistic approach, including medical, aesthetic, and emotional support.

A boy with a rare form of early puberty caused by a new gene mutation responded well to treatment aimed at reducing testosterone and preserving adult height.

Nourkrin® with Marilex® may increase hair count by 35.7% in postpartum hair loss.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

Pigs without the Hairless gene showed skin and thymus changes, useful for studying human hair disorders.

Finasteride treatment changes Cx43 in rat testes, possibly causing fertility issues.

Organic selenium may offer better retention and less waste in puppies.

Low vitamin D and ferritin levels are linked to female hair loss.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Some chemicals can permanently or temporarily remove color from skin and hair, which can be distressing and is not well-regulated in cosmetics.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.